The STIM-Orai Pathway: Conformational Coupling Between STIM and Orai in the Activation of Store-Operated Ca2+ Entry.
暂无分享,去创建一个
[1] J. Putney,et al. The functions of store-operated calcium channels. , 2017, Biochimica et biophysica acta. Molecular cell research.
[2] M. Trebak,et al. The STIM1-binding site nexus remotely controls Orai1 channel gating , 2016, Nature Communications.
[3] Richard S Lewis,et al. Functional Analysis of Orai1 Concatemers Supports a Hexameric Stoichiometry for the CRAC Channel. , 2016, Biophysical journal.
[4] M. Trebak,et al. The Orai1 Store-operated Calcium Channel Functions as a Hexamer*♦ , 2016, The Journal of Biological Chemistry.
[5] C. Romanin,et al. Molecular mechanisms of STIM/Orai communication , 2016, American journal of physiology. Cell physiology.
[6] Richard S Lewis,et al. The inactivation domain of STIM1 is functionally coupled with the Orai1 pore to enable Ca2+-dependent inactivation , 2016, The Journal of general physiology.
[7] Richard S Lewis,et al. Orai1 pore residues control CRAC channel inactivation independently of calmodulin , 2016, The Journal of general physiology.
[8] N. Loktionova,et al. STIM1 dimers undergo unimolecular coupling to activate Orai1 channels , 2015, Nature Communications.
[9] Andriy V. Yeromin,et al. Nanoscale patterning of STIM1 and Orai1 during store-operated Ca2+ entry , 2015, Proceedings of the National Academy of Sciences.
[10] Shenyuan L. Zhang,et al. Inside-out Ca2+ signalling prompted by STIM1 conformational switch , 2015, Nature Communications.
[11] E. Isacoff,et al. Critical role for Orai1 C-terminal domain and TM4 in CRAC channel gating , 2015, Cell Research.
[12] M. Prakriya,et al. Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding , 2015, PloS one.
[13] C. Romanin,et al. Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation , 2015, Proceedings of the National Academy of Sciences.
[14] M. Trebak,et al. Calcium signals tune the fidelity of transcriptional responses. , 2015, Molecular cell.
[15] A. Parekh,et al. Distinct Spatial Ca2+ Signatures Selectively Activate Different NFAT Transcription Factor Isoforms , 2015, Molecular cell.
[16] D. Tobias,et al. Molecular biophysics of Orai store-operated Ca2+ channels. , 2015, Biophysical journal.
[17] M. Prakriya,et al. Structural and functional mechanisms of CRAC channel regulation. , 2015, Journal of molecular biology.
[18] C. Romanin,et al. A Coiled-coil Clamp Controls Both Conformation and Clustering of Stromal Interaction Molecule 1 (STIM1)* , 2014, The Journal of Biological Chemistry.
[19] P. Hogan,et al. STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel , 2014, Nature Communications.
[20] M. Andrake,et al. Distinct Orai-Coupling Domains in Stim1 and Stim2 Define the Orai-Activating Site , 2014 .
[21] C. Romanin,et al. STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry , 2013, Nature Communications.
[22] C. Romanin,et al. The Extended Transmembrane Orai1 N-terminal (ETON) Region Combines Binding Interface and Gate for Orai1 Activation by STIM1*♦ , 2013, The Journal of Biological Chemistry.
[23] M. Ikura,et al. Initial activation of STIM1, the regulator of store-operated calcium entry , 2013, Nature Structural &Molecular Biology.
[24] M. Prakriya,et al. The C‐ and N‐terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels , 2013, The Journal of physiology.
[25] Youjun Wang,et al. Orai Channel Pore Properties and Gating by STIM: Implications from the Orai Crystal Structure , 2013, Science Signaling.
[26] L. Kuo,et al. Differential Roles of the C and N Termini of Orai1 Protein in Interacting with Stromal Interaction Molecule 1 (STIM1) for Ca2+ Release-activated Ca2+ (CRAC) Channel Activation* , 2013, The Journal of Biological Chemistry.
[27] S. Long,et al. Crystal Structure of the Calcium Release–Activated Calcium Channel Orai , 2012, Science.
[28] M. Madesh,et al. STIM proteins: dynamic calcium signal transducers , 2012, Nature Reviews Molecular Cell Biology.
[29] X. Yang,et al. Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1) , 2012, Proceedings of the National Academy of Sciences.
[30] Richard S Lewis,et al. Stoichiometric requirements for trapping and gating of Ca2+ release-activated Ca2+ (CRAC) channels by stromal interaction molecule 1 (STIM1) , 2011, Proceedings of the National Academy of Sciences.
[31] Tao Xu,et al. Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits , 2011, Cell Research.
[32] R. Penner,et al. A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating , 2010, The Journal of general physiology.
[33] Elizabeth D. Covington,et al. Essential Role for the CRAC Activation Domain in Store-dependent Oligomerization of STIM1 , 2010, Molecular biology of the cell.
[34] P. Hogan,et al. STIM1 gates the store-operated calcium channel ORAI1 in vitro , 2010, Nature Structural &Molecular Biology.
[35] G. Barritt,et al. Properties of Orai1 mediated store‐operated current depend on the expression levels of STIM1 and Orai1 proteins , 2009, The Journal of physiology.
[36] Marko Popovic,et al. Dependence of STIM1/Orai1-mediated Calcium Entry on Plasma Membrane Phosphoinositides* , 2009, The Journal of Biological Chemistry.
[37] C. Romanin,et al. A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels* , 2009, Journal of Biological Chemistry.
[38] Elizabeth D. Covington,et al. STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1 , 2009, Cell.
[39] Joseph P. Yuan,et al. SOAR and the polybasic STIM1 domains gate and regulate the Orai channels , 2009, Nature Cell Biology.
[40] Tao Xu,et al. Mapping the Interacting Domains of STIM1 and Orai1 in Ca2+ Release-activated Ca2+ Channel Activation* , 2007, Journal of Biological Chemistry.
[41] Hiroyuki Watanabe,et al. Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry. , 2007, Biochemical and biophysical research communications.
[42] J. Putney,et al. Store-operated calcium channels. , 2005, Physiological reviews.