Does the accuracy of single reading with CAD (computer-aided detection) compare with that of double reading?: A review of the literature.

AIM To examine current evidence to determine whether the accuracy of single reading with computed-aided detection (CAD) compares with that of double reading. METHODS We performed a literature review to identify studies where both protocols had been investigated and compared. We identified eight studies that compared single reading with CAD against double reading, of which six reported on comparisons of both sensitivity and specificity. RESULTS Of the six studies identified, three showed no differences in either sensitivity or specificity. One showed single reading with CAD had a higher sensitivity at the same specificity, another that single reading with CAD had a higher specificity at the same sensitivity. However, one study, in a real-life setting, showed that single reading with CAD had a higher sensitivity but a lower specificity. CONCLUSION As the majority of the studies were not in a real-life setting, used test sets, lacked sufficient training in the use of CAD and simulated double reading (using a protocol of recall if one suggests), current evidence is therefore limited as to the accuracy, in terms of sensitivity and specificity, of single reading with CAD in comparison with the most common practice in the UK of double reading using a protocol of consensus or arbitration.

[1]  P. Taylor,et al.  Assessing the impact of CAD on the sensitivity and specificity of film readers. , 2004, Clinical radiology.

[2]  S Ciatto,et al.  Comparison of standard and double reading and computer-aided detection (CAD) of interval cancers at prior negative screening mammograms: blind review , 2003, British Journal of Cancer.

[3]  B. Muir,et al.  The efficacy of double reading mammograms in breast screening. , 1994, Clinical radiology.

[4]  Nico Karssemeijer,et al.  Computer-aided detection versus independent double reading of masses on mammograms. , 2003, Radiology.

[5]  R. Blanks,et al.  A comparison of cancer detection rates achieved by breast cancer screening programmes by number of readers, for one and two view mammography: results from the UK National Health Service breast screening programme , 1998, Journal of medical screening.

[6]  S. Ciatto,et al.  Comparison of standard reading and computer aided detection (CAD) on a national proficiency test of screening mammography. , 2003, European journal of radiology.

[7]  Marco Zappa,et al.  Comparison of standard reading and computer aided diagnosis (CAD) on a proficiency test of screening mammography. , 2003, La Radiologia medica.

[8]  Julie Cooke,et al.  QUALITY ASSURANCE GUIDELINES FOR BREAST CANCER SCREENING RADIOLOGY , 2005 .

[9]  Stefano Ciatto,et al.  Comparison of two commercial systems for computer-assisted detection (CAD) as an aid to interpreting screening mammograms. , 2004, La Radiologia medica.

[10]  E. Thurfjell,et al.  Benefit of independent double reading in a population-based mammography screening program. , 1994, Radiology.

[11]  P. Taylor,et al.  Computer-aided detection in the United Kingdom National Breast Screening Programme: prospective study. , 2005, Radiology.

[12]  Susan M Astley,et al.  Single reading with computer-aided detection and double reading of screening mammograms in the United Kingdom National Breast Screening Program. , 2006, Radiology.