Analysis of Segmentation Algorithms in Colour Fundus and OCT Images for Glaucoma Detection

Glaucoma is the largesteye disease which affects the optic nerve head and results in visual impairment. In this paper, we analyze the various segmentation algorithms for glaucoma detection using color fundus images and spectral domain Optical Coherence Tomography (OCT) images of same subjects. In fundus images, the disc and the cup regions are segmented separately with four different segmentation algorithms namely Otsu method, Region growing, Hill climbing and Fuzzy C-means clustering algorithms. In OCT images, the cup and the disc diameter were measured by segmenting the retinal nerve fibre and retinal pigment epithelium layers. From both the analysis, the Cup to Disc Ratio (CDR) is calculated and compared with the clinical values. The experimental results show that the performance error in the OCT image analysis is less when compared to the fundus image analysis. Thus, it can be concluded that glaucoma detection can be done more effectively using OCT image analysis.

[1]  T. Ohashi Hill-Climbing Algorithm for Efficient Color-Based Image Segmentation , 2003 .

[2]  U. Rajendra Acharya,et al.  Automated Diagnosis of Glaucoma Using Digital Fundus Images , 2009, Journal of Medical Systems.

[3]  J. Liu,et al.  Optic cup and disk extraction from retinal fundus images for determination of cup-to-disc ratio , 2008, 2008 3rd IEEE Conference on Industrial Electronics and Applications.

[4]  Tien Yin Wong,et al.  Optic disc region of interest localization in fundus image for Glaucoma detection in ARGALI , 2010, 2010 5th IEEE Conference on Industrial Electronics and Applications.

[5]  Qi Yang,et al.  Automated layer segmentation of macular OCT images using dual-scale gradient information. , 2010, Optics express.

[6]  Jayanthi Sivaswamy,et al.  Optic disk and cup boundary detection using regional information , 2010, 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[7]  S. Karthikeyan,et al.  Neuroretinal rim Quantification in Fundus Images to Detect Glaucoma , 2010 .

[8]  Tun-Wen Pai,et al.  An Atomatic Fundus Image Analysis System for Clinical Diagnosis of Glaucoma , 2011, 2011 International Conference on Complex, Intelligent, and Software Intensive Systems.

[9]  K. Duraiswamy,et al.  AN EFFICIENT DECISION SUPPORT SYSTEM FOR DETECTION OF GLAUCOMA IN FUNDUS IMAGES USING ANFIS , 2012 .

[10]  Tien Yin Wong,et al.  Superpixel Classification Based Optic Disc and Optic Cup Segmentation for Glaucoma Screening , 2013, IEEE Transactions on Medical Imaging.

[11]  Mahesh S. Kumbhar,et al.  Optic cup and disc localization for Detection of glaucoma using Matlab , 2014 .

[12]  Shruti Gujral,et al.  Assessment of Disc Damage Likelihood Scale (DDLS) for Automated Glaucoma Diagnosis , 2014, Complex Adaptive Systems.

[13]  T. R. Ganesh Babu,et al.  GLAUCOMA DIAGNOSIS OF MORPHOLOGICAL PROCESSING IN OPTICAL COHERENCE TOMOGRAPHY , .