Genome duplication led to highly selective expansion of the Arabidopsis thaliana proteome.

Multiple ancient genome duplications in Arabidopsis thaliana provide unique opportunities to assess factors that influence the fates of duplicated genes. We have found that genes retained in duplicate following one round of genome duplication are significantly more likely to be retained in duplicate again after a subsequent genome duplication. Genes retained in duplicate form a functionally biased set and include a significant over-representation of genes involved in the regulation of transcription.

[1]  K. H. Wolfe,et al.  Extent of genomic rearrangement after genome duplication in yeast. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[2]  The Arabidopsis Genome Initiative.  Analysis of the genome sequence of the flowering plant Arabidopsis thaliana , 2000, Nature.

[3]  S. Tanksley,et al.  Comparing sequenced segments of the tomato and Arabidopsis genomes: large-scale duplication followed by selective gene loss creates a network of synteny. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[4]  Richard W. Lusk,et al.  Organismal complexity, protein complexity, and gene duplicability , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[5]  M. Ashburner,et al.  Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.

[6]  Brad A. Chapman,et al.  Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events , 2003, Nature.

[7]  K. Hokamp,et al.  A recent polyploidy superimposed on older large-scale duplications in the Arabidopsis genome. , 2003, Genome research.

[8]  J. Birchler,et al.  Effects of reunited diverged regulatory hierarchies in allopolyploids and species hybrids. , 2003, Trends in genetics : TIG.

[9]  K. H. Wolfe,et al.  Molecular evidence for an ancient duplication of the entire yeast genome , 1997, Nature.

[10]  A. Hughes,et al.  Parallel evolution by gene duplication in the genomes of two unicellular fungi. , 2003, Genome research.

[11]  E. Koonin,et al.  Selection in the evolution of gene duplications , 2002, Genome Biology.

[12]  Vincent Colot,et al.  Understanding mechanisms of novel gene expression in polyploids. , 2003, Trends in genetics : TIG.

[13]  Jonathan A. Eisen,et al.  The age of the Arabidopsis thaliana genome duplication , 2003, Plant Molecular Biology.

[14]  D. G. Brown,et al.  The origins of genomic duplications in Arabidopsis. , 2000, Science.

[15]  Jonathan F. Wendel,et al.  Genes duplicated by polyploidy show unequal contributions to the transcriptome and organ-specific reciprocal silencing , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[16]  Klaas Vandepoele,et al.  The hidden duplication past of Arabidopsis thaliana , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[17]  K. H. Wolfe.  Yesterday's polyploids and the mystery of diploidization , 2001, Nature Reviews Genetics.

[18]  M. Lynch,et al.  The evolutionary fate and consequences of duplicate genes. , 2000, Science.

[19]  K. H. Wolfe,et al.  Yeast genome evolution in the post-genome era. , 1999, Current opinion in microbiology.

[20]  J. Birchler,et al.  Dosage-dependent gene regulation in multicellular eukaryotes: implications for dosage compensation, aneuploid syndromes, and quantitative traits. , 2001, Developmental biology.

[21]  C. Pál,et al.  Dosage sensitivity and the evolution of gene families in yeast , 2003, Nature.