PMN-PT Single Crystal Ultrasonic Transducer With Half-Concave Geometric Design for IVUS Imaging

As the key component of intravascular ultrasound (IVUS) imaging systems, traditional commercial side-looking IVUS transducers are flat and unfocused, which limits their lateral resolution. We propose a PMN-PT single crystal IVUS transducer with a half-concave geometry. This unique configuration makes it possible to conduct geometric focusing at a desired depth. To compare performances, the proposed and the traditional flat transducer with similar dimensions were fabricated. We determined that the half-concave transducer has a slightly higher center frequency (35 MHz), significantly broader −6 dB bandwidth (54%) but a higher insertion loss (−22.4 dB) compared to the flat transducer (32 MHz, 28%, and −19.3 dB, respectively). A significant enhancement of the lateral resolution was also confirmed. The experimental results are in agreement with the finite element simulation results. This preliminary investigation suggests that the half-concave geometry design is a promising approach in the development of focused IVUS transducers with broad bandwidth and high lateral resolution.

[1]  Gijs van Soest,et al.  Intravascular photoacoustic imaging: a new tool for vulnerable plaque identification. , 2014, Ultrasound in medicine & biology.

[2]  Qifa Zhou,et al.  Integrated IVUS-OCT Imaging for Atherosclerotic Plaque Characterization , 2014, IEEE Journal of Selected Topics in Quantum Electronics.

[3]  Yung-Chun Lee,et al.  Broadband Poly(vinylidene fluoride-trifluoroethylene) Ultrasound Focusing Transducers for Determining Elastic Constants of Coating Materials , 2009 .

[4]  Xiaoning Jiang,et al.  Design factors of intravascular dual frequency transducers for super-harmonic contrast imaging and acoustic angiography , 2015, Physics in medicine and biology.

[5]  Qifa Zhou,et al.  An open system for intravascular ultrasound imaging , 2012, 2012 IEEE International Ultrasonics Symposium.

[6]  Shuvo Roy,et al.  Demonstration of second-harmonic IVUS feasibility with focused broadband miniature transducers , 2010, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[7]  K. Cheung,et al.  PMN-PT single crystal focusing transducer fabricated using a mechanical dimpling technique. , 2012, Ultrasonics.

[8]  E. S. Kim,et al.  Self-focused high frequency ultrasonic transducers based on ZnO piezoelectric films , 2007 .

[9]  Takahiko Suzuki,et al.  Safety and feasibility of an intravascular optical coherence tomography image wire system in the clinical setting. , 2008, The American journal of cardiology.

[10]  Stanislav Emelianov,et al.  Intravascular Photoacoustics for Image-Guidance and Temperature Monitoring During Plasmonic Photothermal Therapy of Atherosclerotic Plaques: A Feasibility Study , 2013, Theranostics.

[11]  Lei Sun,et al.  An FPGA-based open platform for ultrasound biomicroscopy , 2012, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[12]  W. Qiu,et al.  A multifunctional, reconfigurable pulse generator for high-frequency ultrasound imaging , 2012, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[13]  Carlos H. F. Alves,et al.  Design, fabrication, and evaluation of high frequency, single-element transducers incorporating different materials , 2002, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[14]  Qifa Zhou,et al.  Micromachined PIN-PMN-PT crystal composite transducer for high-frequency intravascular ultrasound (IVUS) imaging , 2014, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[15]  Patrick W Serruys,et al.  Coronary Restenosis After Sirolimus‐Eluting Stent Implantation: Morphological Description and Mechanistic Analysis From a Consecutive Series of Cases , 2003, Circulation.

[16]  A. Yeung,et al.  Multicenter intravascular ultrasound validation study among heart transplant recipients: outcomes after five years. , 2005, Journal of the American College of Cardiology.

[17]  M. Fink,et al.  Energy-based adaptive focusing of waves: Application to ultrasonic imaging and therapy , 2008, 2008 IEEE Ultrasonics Symposium.

[18]  Pai-Chi Li,et al.  Design and fabrication of a 40MHz transducer with enhanced bandwidth , 2008, 2008 IEEE Ultrasonics Symposium.

[19]  Franck Levassort,et al.  Lens-focused transducer modeling using an extended KLM model. , 2007, Ultrasonics.

[20]  Stephen J. Nicholls,et al.  Application of intravascular ultrasound in anti-atherosclerotic drug development , 2006, Nature reviews. Drug discovery.

[21]  Stanislav Emelianov,et al.  In vivo intravascular ultrasound-guided photoacoustic imaging of lipid in plaques using an animal model of atherosclerosis. , 2012, Ultrasound in medicine & biology.

[22]  J Chen,et al.  Bandwidth improvement of LiNbO3 ultrasonic transducers by half-concaved inversion layer approach. , 2012, The Review of scientific instruments.

[23]  Pengbo Liu,et al.  Fabrication and performance of a micro 50-MHz IVUS Transducer based on a 1-3 composite with geometric focusing , 2015, 2015 IEEE International Ultrasonics Symposium (IUS).

[24]  Raimund Erbel,et al.  Serial intravascular ultrasound assessment of changes in coronary atherosclerotic plaque dimensions and composition: an update. , 2011, European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology.

[25]  Yoni Hertzberg,et al.  Ultrasound focusing using magnetic resonance acoustic radiation force imaging: Application to ultrasound transcranial therapy. , 2010, Medical physics.

[26]  Wei Wu,et al.  80-MHz intravascular ultrasound transducer using PMN-PT free-standing film , 2011, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[27]  N Bom,et al.  Characterization of plaque components and vulnerability with intravascular ultrasound elastography. , 2000, Physics in medicine and biology.

[28]  Qifa Zhou,et al.  Intravascular photoacoustic imaging at 35 and 80 MHz , 2012, Journal of biomedical optics.

[29]  Qifa Zhou,et al.  Multi-frequency intravascular ultrasound (IVUS) imaging , 2015, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[30]  Xiaoning Jiang,et al.  High Frequency Piezo Composites Microfabricated Ultrasound Transducers for Intravascular Imaging , 2006 .

[31]  D. A. Christopher,et al.  Advances in ultrasound biomicroscopy. , 2000, Ultrasound in medicine & biology.

[32]  Qifa Zhou,et al.  PMN-PT single crystal, high-frequency ultrasonic needle transducers for pulsed-wave Doppler application , 2007, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[33]  R D Gordon,et al.  Mycophenolate Mofetil Reduces Intimal Thickness by Intravascular Ultrasound After Heart Transplant: Reanalysis of the Multicenter Trial , 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[34]  Timothy A. Ritter,et al.  Design of focused single element (50-100 MHz) transducers using lithium niobate , 2000, 2000 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.00CH37121).