Fraktionale Laser: Wunsch und Wirklichkeit

Zusammenfassung Die neuen Erkenntnisse zu den Möglichkeiten der fraktional therapierten Haut haben konsequenterweise zur Etablierung von neuen Standardverfahren insbesondere im Bereich der gealterten Haut und bei Narben geführt. Daneben wird das Potenzial aber auch auf fibrosierende Dermatosen, Fremdkörperentfernung, inflammatorische Hauterkrankungen und vieles mehr erweitert. Das größte Potenzial jedoch hat die kontaktfreie temporäre Eröffnung der Hautbarriere (TOR, temporary opening of the epidermal barrier). Das TOR zur Haut hat im wahrsten Sinne des Wortes die Potenz, Zugang zu neuen und intensivierten Therapieformen zu ermöglichen. Vieles liegt hier allerdings noch im experimentellen Bereich, die ersten Ergebnisse sind jedoch mehr als vielversprechend. So zeigt eine erste klinische Studie Überlegenheit der durch fraktionale Laser intensivierten PDT bei der Therapie der aktinischen Keratose. Risiken können sich allerdings infolge der schon erhältlichen Heimgeräte im Zusammenhang mit der Anwendung jedweder Topika im Sinne toxischer Reaktionen oder Sensibilisierungen ergeben. Die Prinzipien der aktuell wirksamen fraktionalen Laserverfahren (Wirklichkeit) und potenzielle Konzepte (Wünsche) werden dargestellt.

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