Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
暂无分享,去创建一个
Michael P Barrett | M. Barrett | H. D. de Koning | S. Ward | Stephen A Ward | P. Bray | Patrick G Bray | Harry P de Koning
[1] H. D. de Koning,et al. Nucleobase transporters (review). , 2000, Molecular membrane biology.
[2] M. Robert-Gero,et al. Alterations in membrane fluidity, lipid metabolism, mitochondrial activity, and lipophosphoglycan expression in pentamidine-resistant Leishmania , 1997, Parasitology Research.
[3] T. Kobayasi,et al. The ultrastructural changes of Leishmania tropica after treatment with pentamidine. , 1977, Annals of tropical medicine and parasitology.
[4] T. Baltz,et al. The efficacy of pentamidine in the treatment of early-late stage Trypanosoma brucei gambiense trypanosomiasis. , 1996, The American journal of tropical medicine and hygiene.
[5] S. Croft. Monitoring drug resistance in leishmaniasis , 2001, Tropical medicine & international health : TM & IH.
[6] A. Fairlamb,et al. Uptake of Diamidine Drugs by the P2 Nucleoside Transporter in Melarsen-sensitive and -resistant Trypanosoma brucei brucei(*) , 1995, The Journal of Biological Chemistry.
[7] T. Baltz,et al. In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium. , 1991, Acta tropica.
[8] M. P. Hutchinson,et al. The efficacy of certain trypanocidal compounds against Trypanosoma gambiense infection in man. , 1951, Transactions of the Royal Society of Tropical Medicine and Hygiene.
[9] J. Jannin,et al. Availability and affordability of treatment for Human African Trypanosomiasis , 2001, Tropical medicine & international health : TM & IH.
[10] A. Fairlamb,et al. Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism. , 1992, Molecular and biochemical parasitology.
[11] H. D. de Koning,et al. Characterization of a Nucleoside/Proton Symporter in ProcyclicTrypanosoma brucei brucei * , 1998, The Journal of Biological Chemistry.
[12] S. Croft,et al. Effect of pentamidine isethionate on the ultrastructure and morphology of Leishmania mexicana amazonensis in vitro. , 1982, Annals of tropical medicine and parasitology.
[13] V. Yardley,et al. Chemotherapy of leishmaniasis. , 2002, Current pharmaceutical design.
[14] T. Fox,et al. Mutations Affecting a Yeast Mitochondrial Inner Membrane Protein, Pnt1p, Block Export of a Mitochondrially Synthesized Fusion Protein from the Matrix , 1999, Molecular and Cellular Biology.
[15] C. Burri,et al. Treatment of human African trypanosomiasis--present situation and needs for research and development. , 2002, The Lancet. Infectious diseases.
[16] J. Soto,et al. Successful treatment of Colombian cutaneous leishmaniasis with four injections of pentamidine. , 1994, The American journal of tropical medicine and hygiene.
[17] A. Stead,et al. Diamidine compounds: selective uptake and targeting in Plasmodium falciparum. , 2001, Molecular pharmacology.
[18] W. Yorke,et al. Studies in Chemotherapy , 1931 .
[19] L. Napier,et al. The Treatment of Kala-Azar by Diamidino Stilbene : Analysis of 101 Cases , 1942, The Indian medical gazette.
[20] V. Devita,et al. he determination of pentamidine (4,4'-diamidinophenoxypentane) in plasma, urine, and tissues. , 1970, The Journal of laboratory and clinical medicine.
[21] H. Ginsburg,et al. Cellular Uptake of Chloroquine Is Dependent on Binding to Ferriprotoporphyrin IX and Is Independent of NHE Activity in Plasmodium falciparum , 1999, The Journal of cell biology.
[22] W. Yorke,et al. Studies in Chemotherapy: XXI.—The Trypanocidal Action of Certain Aromatic Diamidines , 1939 .
[23] C. Patton,et al. Pentamidine transport in Trypanosoma brucei-kinetics and specificity. , 1976, Biochemical pharmacology.
[24] D. Kyle,et al. Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis , 1990, Antimicrobial Agents and Chemotherapy.
[25] D. Sereno,et al. In vitro life cycle of pentamidine-resistant amastigotes: stability of the chemoresistant phenotypes is dependent on the level of resistance induced , 1997, Antimicrobial agents and chemotherapy.
[26] C. Burri,et al. The phenomenon of treatment failures in Human African Trypanosomiasis , 2001, Tropical medicine & international health : TM & IH.
[27] W. Yorke,et al. NEW TRYPANOCIDAL SUBSTANCES , 1937 .
[28] L. Napier,et al. A Peculiar Neurological Sequel to Administration of 4: 4′-Diamidino-Diphenyl-Ethylene (M.&B. 744) , 1942, The Indian medical gazette.
[29] H. D. de Koning,et al. Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter. , 2001, Acta tropica.
[30] M. Badet-Denisot,et al. Modification of kinetoplast DNA minicircle composition in pentamidine-resistant Leishmania. , 1998, Acta tropica.
[31] A. Fairlamb,et al. Arsenical-resistant trypanosomes lack an unusual adenosine transporter , 1993, Nature.
[32] R. D. Harding. Late results of treatment of sleeping sickness in Sierra Leone by antrypol tryparsamide pentamidine and propamidine singly and in various combinations. , 1945, Transactions of the Royal Society of Tropical Medicine and Hygiene.
[33] T. Shapiro,et al. Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[34] R. Reguera,et al. Putrescine uptake inhibition by aromatic diamidines in Leishmania infantum promastigotes. , 1994, Biochemical pharmacology.
[35] R. Kaminsky,et al. Susceptibility of Ugandan Trypanosoma brucei rhodesiense isolated from man and animal reservoirs to diminazene, isometamidium and melarsoprol , 1997, Tropical medicine & international health : TM & IH.
[36] H. D. de Koning. Transporters in African trypanosomes: role in drug action and resistance. , 2001, International journal for parasitology.
[37] S. Moreno,et al. Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondria. , 1996, Archives of biochemistry and biophysics.
[38] A. Fairlamb,et al. The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes. , 1999, Parasitology today.
[39] E. Greenspan,et al. THE PHARMACOLOGY, MODE OF ACTION AND THERAPEUTIC POTENTIALITIES OF STILBAMIDINE, PENTAMIDINE, PROPAMIDINE AND OTHER AROMATIC DIAMIDINES—A REVIEW , 1948, Medicine.
[40] C. Staben,et al. Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae , 1994, Antimicrobial Agents and Chemotherapy.
[41] A. Fairlamb,et al. Characterisation of pentamidine-resistant Trypanosoma brucei brucei. , 1995, Molecular and biochemical parasitology.
[42] M. Barrett,et al. Resistance to Pentamidine in Leishmania mexicana Involves Exclusion of the Drug from the Mitochondrion , 2002, Antimicrobial Agents and Chemotherapy.
[43] B. Tekwani,et al. Kinetics and molecular characteristics of arginine transport by Leishmania donovani promastigotes. , 1995, Molecular and biochemical parasitology.
[44] C. Patton,et al. Pentamidine transport and sensitivity in brucei-group trypanosomes. , 1976, The Journal of protozoology.
[45] H. D. Koning,et al. Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals. , 2001 .
[46] D. Sereno,et al. Phenotypic characterization of Leishmania mexicana pentamidine-resistant promastigotes. Modulation of the resistance during in-vitro developmental life cycle. , 1997, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.
[47] Kiaran Kirk,et al. Membrane Transport in the Malaria-Infected Erythrocyte , 2001 .
[48] M. Kron,et al. Pentamidine: a review. , 1985, Reviews of infectious diseases.
[49] A. Vercesi,et al. Ca2+ transport by digitonin-permeabilized Leishmania donovani. Effects of Ca2+, pentamidine and WR-6026 on mitochondrial membrane potential in situ. , 1992, The Biochemical journal.
[50] R. Kaminsky,et al. A nucleoside transporter from Trypanosoma brucei involved in drug resistance. , 1999, Science.
[51] H. D. de Koning,et al. Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs. , 1999, Molecular pharmacology.
[52] Giri Op. Treatment of visceral Leishmaniasis unresponsive to pentamidine with amphotericin B. , 1994 .
[53] R. Kaminsky,et al. Melarsoprol refractory T. b. gambiense from Omugo, north‐western Uganda , 2001, Tropical medicine & international health : TM & IH.
[54] M. Badet-Denisot,et al. Effects of pentamidine on polyamine level and biosynthesis in wild-type, pentamidine-treated, and pentamidine-resistant Leishmania. , 1997, Experimental parasitology.
[55] M. Barrett,et al. Putrescine and spermidine transport in Leishmania. , 2000, Molecular and biochemical parasitology.
[56] D. Legros,et al. Trypanosomiase humaine africaine: historique de la thérapeutique et de ses échecs , 2001 .
[57] J. Zimmerberg,et al. A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite , 2000, Nature.
[58] I. Becker,et al. The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis , 1999, Parasitology Research.
[59] E. Peel,et al. Pentamidine in the Prevention and Treatment of Trypanosomiasis. , 1944 .
[60] W. Mulugeta,et al. Modulation of mitochondrial electrical potential: a candidate mechanism for drug resistance in African trypanosomes. , 1997, The Biochemical journal.
[61] D. Sullivan,et al. Hemoglobin metabolism in the malaria parasite Plasmodium falciparum. , 1997, Annual review of microbiology.
[62] M. Robert-Gero,et al. Altered transport properties of pentamidine-resistant Leishmania donovani and L. amazonensis promastigotes , 1997, Parasitology Research.