Does SISCOM Contribute to Favorable Seizure Outcome after Epilepsy Surgery?

Summary:  Purpose: To assess the additional value of subtraction ictal single‐photon emission computed tomography (SPECT) coregistered to MRI (SISCOM) for localization of the epileptogenic zone in patients with drug‐resistant epilepsy scheduled for invasive video‐EEG (VEEG) before epilepsy surgery by a descriptive study from clinical practice.

[1]  O Delalande,et al.  Ictal SPECT in children with epilepsy: comparison with intracranial EEG and relation to postsurgical outcome. , 2003, Brain : a journal of neurology.

[2]  Soheyl Noachtar,et al.  Epileptic Seizures: Pathophysiology And Clinical Semiology , 2000 .

[3]  A. Andersen.  99mTc-D,L-hexamethylene-propyleneamine oxime (99mTc-HMPAO): basic kinetic studies of a tracer of cerebral blood flow. , 1989, Cerebrovascular and brain metabolism reviews.

[4]  C D Binnie,et al.  Is it worth pursuing surgery for epilepsy in patients with normal neuroimaging? , 2006, Journal of Neurology, Neurosurgery & Psychiatry.

[5]  E. So.  Integration of EEG, MRI, and SPECT in Localizing the Seizure Focus for Epilepsy Surgery , 2000, Epilepsia.

[6]  F. Sharbrough,et al.  Subtraction SPECT Coregistered to MRI in Focal Malformations of Cortical Development: Localization of the Epileptogenic Zone in Epilepsy Surgery Candidates , 2004, Epilepsia.

[7]  Andersen Ar,et al.  99mTc-D,L-hexamethylene-propyleneamine oxime (99mTc-HMPAO): basic kinetic studies of a tracer of cerebral blood flow. , 1989 .

[8]  G. Cascino,et al.  Ictal SPECT in Nonlesional Extratemporal Epilepsy , 2004, Epilepsia.

[9]  S. Spencer,et al.  Periictal SPECT Localization Verified by Simultaneous Intracranial EEG , 1999, Epilepsia.

[10]  B. Geijer,et al.  Ictal SPECT in clinical perisylvian syndrome , 2004, Acta neurologica Scandinavica.

[11]  G. Cascino,et al.  Advances in Neuroimaging: Surgical Localization , 2001 .

[12]  Val J Lowe,et al.  The Usefulness of Subtraction Ictal SPECT Coregistered to MRI in Single‐ and Dual‐headed SPECT Cameras in Partial Epilepsy , 2002, Epilepsia.

[13]  Tobias Loddenkemper,et al.  Specific Epileptic Syndromes Are Rare Even in Tertiary Epilepsy Centers: A Patient‐oriented Approach to Epilepsy Classification , 2004, Epilepsia.

[14]  B H Brinkmann,et al.  Subtraction SPECT co-registered to MRI improves postictal SPECT localization of seizure foci , 1999, Neurology.

[15]  D. Gregory.  The 1999 William G. Lennox Lecture of the American Epilepsy Society : Advances in Neuroimaging : Surgical Localization , 2001 .

[16]  G. Cascino,et al.  Advances in neuroimaging: management of partial epileptic syndromes , 2003, Neurosurgical Review.

[17]  B. Brinkmann,et al.  Subtraction peri-ictal SPECT is predictive of extratemporal epilepsy surgery outcome , 2000, Neurology.

[18]  C. Jack,et al.  Subtraction ictal SPECT co‐registered to MRI improves clinical usefulness of SPECT in localizing the surgical seizure focus , 1998, Neurology.

[19]  Jerome Engel,et al.  Outcome with respect to epileptic seizures. , 1993 .

[20]  D W Roberts,et al.  Medically Intractable, Localization‐related Epilepsy with Normal MRI: Presurgical Evaluation and Surgical Outcome in 43 Patients , 2001, Epilepsia.