Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029.

[1]  B. Shen,et al.  A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase. , 2015, Molecular bioSystems.

[2]  M. Smanski,et al.  Isolation and structural elucidation of glucoside congeners of platencin from Streptomyces platensis SB12600 , 2013, The Journal of Antibiotics.

[3]  M. Smanski,et al.  Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners. , 2012, Journal of natural products.

[4]  A. Demain,et al.  Platensimycin and platencin: promising antibiotics for future application in human medicine , 2011, The Journal of Antibiotics.

[5]  M. Saleem,et al.  Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics. , 2011, Natural product reports.

[6]  M. Smanski,et al.  Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis , 2011, Proceedings of the National Academy of Sciences.

[7]  Margaret S. Wu,et al.  Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes , 2011, Proceedings of the National Academy of Sciences.

[8]  M. Smanski,et al.  Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners. , 2010, Organic letters.

[9]  M. Motyl,et al.  Isolation, structure and biological activities of platencin A(2)-A(4) from Streptomyces platensis. , 2010, Bioorganic & medicinal chemistry.

[10]  Koen Andries,et al.  Essentiality of FASII pathway for Staphylococcus aureus , 2010, Nature.

[11]  Z. Guan,et al.  Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis , 2009, The Journal of Antibiotics.

[12]  J. W. Becker,et al.  Isolation, enzyme-bound structure, and activity of platensimycin A1 from Streptomyces platensis , 2009 .

[13]  G. Besra,et al.  Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases , 2009, PloS one.

[14]  B. Staels,et al.  Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens , 2009, Nature.

[15]  M. Smanski,et al.  Engineered Streptomyces platensis Strains That Overproduce Antibiotics Platensimycin and Platencin , 2009, Antimicrobial Agents and Chemotherapy.

[16]  R. Hancock,et al.  Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances , 2008, Nature Protocols.

[17]  R. Ball,et al.  Chemistry of platensimycin , 2007 .

[18]  F. Vicente,et al.  Isolation and structure of platencin: a FabH and FabF dual inhibitor with potent broad-spectrum antibiotic activity. , 2007, Angewandte Chemie.

[19]  Jun Wang,et al.  Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties , 2007, Proceedings of the National Academy of Sciences.

[20]  R. Jackson,et al.  Thioquinolobactin, a Pseudomonas siderophore with antifungal and anti-Pythium activity. , 2007, Environmental microbiology.

[21]  F. McLafferty,et al.  Biosynthesis of the Thioquinolobactin Siderophore: an Interesting Variation on Sulfur Transfer , 2007, Journal of bacteriology.

[22]  Olga Genilloud,et al.  Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy. , 2006, Journal of the American Chemical Society.

[23]  Jun Wang,et al.  Platensimycin is a selective FabF inhibitor with potent antibiotic properties , 2006, Nature.

[24]  H. De Greve,et al.  The Pseudomonas siderophore quinolobactin is synthesized from xanthurenic acid, an intermediate of the kynurenine pathway , 2004, Molecular microbiology.

[25]  T. Shioiri,et al.  New Methods and Reagents in Organic Synthesis. 14. A Simple Efficient Preparation of Methyl Esters with Trimethylsilyldiazomethane (TMSCHN2) and Its Application to Gas Chromatographic Analysis of Fatty Acids , 1981 .