Relationship between the results of skin, conjunctival and bronchial tests and RAST with Candida albicans in patients with asthma

The results of the skin, conjunctival and inhalation tests and RAST with Candida antigen were compared with each other in patients with bronchial asthma. The correlation coefficient between the skin test and RAST was 0‐50 (P<0.01). The correlation coefficient between the skin test, RAST and the inhalation tests was 0.36 (P < 0.01) and 0 57 (P < 0.01). The positive agreement of the inhalation test to the skin test, RAST and the conjunctival test was 77, 86 and 93%, respectively. In this study the conjunctival test was thought to be the best method in place of the inhalation test. There was no significant relation between the serum IgE concentration and the endpoint of the skin titration testing, and a low correlation was noticed between the serum IgE concentration and RAST counts (r= 0.36).

[1]  C. Collins-Williams,et al.  Comparison of skin tests and RAST in the diagnosis of atopic hypersensitivity. , 1976, Annals of allergy.

[2]  J. Longbottom,et al.  Antibodies mediating type I skin test reactions to polysaccharide and protein antigens of Candida albicans , 1976, Clinical allergy.

[3]  L. Lazarus,et al.  The correlation between skin tests, bronchial provocation tests and the serum level of IgE specific for common allergens in patients with asthma , 1975, Clinical allergy.

[4]  J. Apold,et al.  The radioallergosorbent test (RAST) in the diagnosis of reaginic allergy , 1974 .

[5]  S. Johansson,et al.  Allergy diagnosis with the radioallergosorbent test: A comparison with the results of skin and provocation tests in an unselected group of children with asthma and hay fever. , 1974, The Journal of allergy and clinical immunology.

[6]  T. Miyamoto,et al.  Relationship of dermal and pulmonary sensitivity to extracts of Candida albicans. , 1971, The American review of respiratory disease.

[7]  J. Apold,et al.  The radioallergosorbent test in the in vitro diagnosis of multiple reaginic allergy , 1971, The Journal of allergy and clinical immunology.

[8]  K. Aas Bronchial Provocation Tests in Asthma , 1970, Archives of disease in childhood.

[9]  L. Wide,et al.  Reaginic antibody (IgE), skin, and provocation tests to Dermatophagoides culinae and house dust in respiratory allergy. , 1969, Lancet.

[10]  F. Hargreave,et al.  Candida albicans precipitins in respiratory disease in man. , 1968, The Journal of allergy.

[11]  L. Wide,et al.  Diagnosis of allergy by an in-vitro test for allergen antibodies. , 1967, Lancet.

[12]  I. Itkin,et al.  Bronchial hypersensitivity to extract of Candida albicans. , 1966, The Journal of allergy.

[13]  T. Miyamoto,et al.  Atopic allergy in Japanese subjects: studies primarily with radioallergosorbent test. , 1974, The Journal of allergy and clinical immunology.

[14]  M. Ceska,et al.  Radioimmunosorbent assay of allergens. , 1972, The Journal of allergy and clinical immunology.

[15]  H. Herxheimer The late bronchial reaction in induced asthma. , 1952, International archives of allergy and applied immunology.

[16]  E. L. Keeney Candida asthma. , 1951, Annals of internal medicine.