Bisphosphonate-incorporated coatings for orthopedic implants functionalization

[1]  S. Patntirapong.  Duration and timing of bisphosphonate treatment as factors determining osteoblast mineralization. , 2022, Journal of oral biology and craniofacial research.

[2]  H. Jung,et al.  Natural bone-mimicking nanopore-incorporated hydroxyapatite scaffolds for enhanced bone tissue regeneration , 2022, Biomaterials Research.

[3]  Ashutosh Kumar Singh,et al.  A comprehensive review on metallic implant biomaterials and their subtractive manufacturing , 2022, The International Journal of Advanced Manufacturing Technology.

[4]  D. Zhao,et al.  Interfacial Assembly of Functional Mesoporous Carbon‐Based Materials into Films for Batteries and Electrocatalysis , 2022, Advanced Materials Interfaces.

[5]  Xin Zhao,et al.  A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions , 2022, Bioactive materials.

[6]  V. Sergienko,et al.  Bisphosphonates: synthesis, structures, properties, medical and industrial applications , 2022, Journal of Molecular Liquids.

[7]  Y. B. Choy,et al.  Synergistic Effect of Whitlockite Scaffolds Combined with Alendronate to Promote Bone Regeneration , 2021, Tissue Engineering and Regenerative Medicine.

[8]  Shijie Zhu,et al.  A drug-loaded bio-functional anticorrosion coating on Mg alloy for orthopedic applications , 2021, Materials Letters.

[9]  Md. Ashikur Rahman,et al.  Dietary chitosan promotes the growth, biochemical composition, gut microbiota, hematological parameters and internal organ morphology of juvenile Barbonymus gonionotus , 2021, PloS one.

[10]  M. Zielińska,et al.  Controlled release of the drug for osteoporosis from the surface of titanium implants coated with calcium titanate. , 2021, Journal of biomedical materials research. Part B, Applied biomaterials.

[11]  C. Ruosi,et al.  In vitro evidence for the involvement of H2S pathway in the effect of clodronate during inflammatory response , 2021, Scientific Reports.

[12]  B. Aderibigbe,et al.  Bisphosphonate-Based Conjugates and Derivatives as Potential Therapeutic Agents in Osteoporosis, Bone Cancer and Metastatic Bone Cancer , 2021, International journal of molecular sciences.

[13]  Yongxing Zhang,et al.  SENP3-Mediated PPARγ2 DeSUMOylation in BM-MSCs Potentiates Glucocorticoid-Induced Osteoporosis by Promoting Adipogenesis and Weakening Osteogenesis , 2021, Frontiers in Cell and Developmental Biology.

[14]  R. Hoffman,et al.  Neddylation Regulates Macrophages and Implications for Cancer Therapy , 2021, Frontiers in Cell and Developmental Biology.

[15]  E. Geven,et al.  Sustained release of ancillary amounts of testosterone and alendronate from PLGA coated pericard membranes and implants to improve bone healing , 2021, PloS one.

[16]  B. Hou,et al.  Evaluation of Silk Fibroin-RGD-Stem Cell Factor Scaffold Effect on Adhesion, Migration, and Proliferation of Stem Cells of Apical Papilla , 2021, Stem cells international.

[17]  M. Elsalanty,et al.  Effect of Age and Sodium Alendronate on Femoral Fracture Repair: Biochemical and Biomechanical Study in Rats , 2021, Frontiers in Cell and Developmental Biology.

[18]  Z. Binkhathlan,et al.  Design and Development of D‒α‒Tocopheryl Polyethylene Glycol Succinate‒block‒Poly(ε-Caprolactone) (TPGS−b−PCL) Nanocarriers for Solubilization and Controlled Release of Paclitaxel , 2021, Molecules.

[19]  He Liu,et al.  Functionalized anti-osteoporosis drug delivery system enhances osseointegration of an inorganic–organic bioactive interface in osteoporotic microenvironment , 2021 .

[20]  T. Maiyalagan,et al.  N‐Doped Carbon Nanotubes Derived from Graphene Oxide with Embedment of FeCo Nanoparticles as Bifunctional Air Electrode for Rechargeable Liquid and Flexible All‐Solid‐State Zinc–Air Batteries , 2021, Advanced science.

[21]  M. Buzgo,et al.  The Effect of Alendronate on Osteoclastogenesis in Different Combinations of M-CSF and RANKL Growth Factors , 2021, Biomolecules.

[22]  Xuetao Shi,et al.  Sustained delivery of growth factors and alendronate using partially demineralized dentin matrix for endogenous periodontal regeneration , 2021 .

[23]  F. A. Almeida Paz,et al.  Bisphosphonates, Old Friends of Bones and New Trends in Clinics. , 2021, Journal of medicinal chemistry.

[24]  Masahiro Yamamoto,et al.  Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins , 2021, Nature Communications.

[25]  A. Rishi,et al.  Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening , 2021, Scientific reports.

[26]  I. Cha,et al.  Effects of pre-extraction intermittent PTH administration on extraction socket healing in bisphosphonate administered ovariectomized rats , 2021, Scientific reports.

[27]  D. Zhao,et al.  Laser Cladding Induced Spherical Graphitic Phases by Super-Assembly of Graphene-Like Microstructures and the Antifriction Behavior , 2020, ACS central science.

[28]  Mi Yang,et al.  Bone and Muscle Crosstalk in Aging , 2020, Frontiers in Cell and Developmental Biology.

[29]  S. Patntirapong,et al.  Assessment of bisphosphonate treated-osteoblast behaviors by conventional assays and a simple digital image analysis. , 2020, Acta histochemica.

[30]  T. Oh,et al.  Biopolymer Coatings for Biomedical Applications , 2020, Polymers.

[31]  M. Vallet‐Regí,et al.  Ipriflavone-Loaded Mesoporous Nanospheres with Potential Applications for Periodontal Treatment , 2020, Nanomaterials.

[32]  D. Djurado,et al.  Analysis of the Calcium Phosphate-Based Hybrid Layer Formed on a Ti-6Al-7Nb Alloy to Enhance the Ossseointegration Process , 2020, Materials.

[33]  Runlan Luo,et al.  Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief review , 2020, BMC Cancer.

[34]  P. N. Lisboa-Filho,et al.  Bisphosphonate-based surface biofunctionalization improves titanium biocompatibility , 2020, Journal of Materials Science: Materials in Medicine.

[35]  M. Martins,et al.  Pequi (Caryocar brasiliense Cambess)-Loaded Nanoemulsion, Orally Delivered, Modulates Inflammation in LPS-Induced Acute Lung Injury in Mice , 2020, Pharmaceutics.

[36]  Xiumei Wang,et al.  Applications of Graphene and Its Derivatives in Bone Repair: Advantages for Promoting Bone Formation and Providing Real-Time Detection, Challenges and Future Prospects , 2020, International journal of nanomedicine.

[37]  Jianru Xiao,et al.  Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges. , 2020, Biomaterials.

[38]  A. Macpherson,et al.  Warmth Prevents Bone Loss Through the Gut Microbiota. , 2020, Cell metabolism.

[39]  Zhihong Zhu,et al.  Photothermal/matrix metalloproteinase-2 dual-responsive gelatin nanoparticles for breast cancer treatment , 2020, Acta pharmaceutica Sinica. B.

[40]  M. Zielińska,et al.  Determination of bisphosphonates anti-resorptive properties based on three forms of ceramic materials: Sorption and release process evaluation , 2020, Journal of pharmaceutical analysis.

[41]  Jian Kang,et al.  Efficacy-shaping nanomedicine by loading Calcium Peroxide into Tumor Microenvironment-responsive Nanoparticles for the Antitumor Therapy of Prostate Cancer , 2020, Theranostics.

[42]  T. Goslinski,et al.  Crosslinking of Chitosan with Dialdehyde Chitosan as a New Approach for Biomedical Applications , 2020, Materials.

[43]  V. Alt,et al.  In Vitro and In Vivo Biocompatibility Studies of a Cast and Coated Titanium Alloy , 2020, Molecules.

[44]  O. Lieleg,et al.  Biopolymer‐Based Coatings: Promising Strategies to Improve the Biocompatibility and Functionality of Materials Used in Biomedical Engineering , 2020, Advanced Materials Interfaces.

[45]  N. Alhakamy,et al.  Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells , 2020, Pharmaceuticals.

[46]  M. Essler,et al.  DOTA-ZOL: A Promising Tool in Diagnosis and Palliative Therapy of Bone Metastasis—Challenges and Critical Points in Implementation into Clinical Routine , 2020, Molecules.

[47]  Muhammad Sohail Zafar,et al.  Customized Therapeutic Surface Coatings for Dental Implants , 2020, Coatings.

[48]  J. Mohammadnejad,et al.  Chitosan Coating of TiO2 Nanotube Arrays for Improved Metformin Release and Osteoblast Differentiation , 2020, International journal of nanomedicine.

[49]  Yingjun Wang,et al.  Calcium alendronate-coated composite scaffolds promote osteogenesis of ADSCs via integrin and FAK/ERK signalling pathways. , 2020, Journal of materials chemistry. B.

[50]  Han Wei Toh,et al.  Bioresorbable Polymeric Scaffold in Cardiovascular Applications , 2020, International journal of molecular sciences.

[51]  A. Moritz,et al.  Effect of bisphosphonate treatment of titanium surfaces on alkaline phosphatase activity in osteoblasts: a systematic review and meta-analysis , 2020, BMC oral health.

[52]  W. Fan,et al.  Effects of Targeted Delivery of Metformin and Dental Pulp Stem Cells on Osteogenesis via Demineralized Dentin Matrix under High Glucose Conditions. , 2020, ACS biomaterials science & engineering.

[53]  W. Xu,et al.  Reduction of SOST gene promotes bone formation through the Wnt/β‐catenin signalling pathway and compensates particle‐induced osteolysis , 2020, Journal of cellular and molecular medicine.

[54]  Bong-Ju Kim,et al.  Effects of gamma irradiation on the measurement of hepatitis B virus DNA in dentin harvested from chronically infected patients , 2020, Annals of translational medicine.

[55]  G. Seymour,et al.  The in vitro effect of VEGF receptor inhibition on primary alveolar osteoblast nodule formation. , 2020, Australian dental journal.

[56]  M. Vallet‐Regí,et al.  Substituted hydroxyapatite coatings of bone implants. , 2020, Journal of materials chemistry. B.

[57]  Ping Li,et al.  Dual targeting of SREBP2 and ERRα by carnosic acid suppresses RANKL-mediated osteoclastogenesis and prevents ovariectomy-induced bone loss , 2020, Cell Death & Differentiation.

[58]  C. Shao,et al.  Harnessing tumor-associated macrophages as aids for cancer immunotherapy , 2019, Molecular Cancer.

[59]  He Liu,et al.  Bisphosphonate‐Functionalized Scaffolds for Enhanced Bone Regeneration , 2019, Advanced healthcare materials.

[60]  F. Dehghani,et al.  A Bioactive Coating Enhances Bone Allografts in Rat Models of Bone Formation and Critical Defect Repair , 2019, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[61]  Yuhai Li,et al.  Facile fabrication of the zoledronate-incorporated coating on magnesium alloy for orthopaedic implants , 2019, Journal of orthopaedic translation.

[62]  M. Longaker,et al.  A Revised Perspective of Skeletal Stem Cell Biology , 2019, Front. Cell Dev. Biol..

[63]  Derek H. Rosenzweig,et al.  Anti-Tumor Effects of Low Dose Zoledronate on Lung Cancer-Induced Spine Metastasis , 2019, Journal of clinical medicine.

[64]  Yuanda Song,et al.  Sources, Extraction and Biomedical Properties of Polysaccharides , 2019, Foods.

[65]  Y. Kasahara,et al.  Bone invasion‐targeted chemotherapy with a novel anionic platinum complex (3Pt) for oral squamous cell carcinoma , 2019, Cancer science.

[66]  A. Bigi,et al.  Multifunctionalization Modulates Hydroxyapatite Surface Interaction with Bisphosphonate: Antiosteoporotic and Antioxidative Stress Materials. , 2019, ACS biomaterials science & engineering.

[67]  Moganavelli Singh,et al.  Polymeric Mesoporous Silica Nanoparticles for Enhanced Delivery of 5-Fluorouracil In Vitro , 2019, Pharmaceutics.

[68]  Hyun-Seok Jin,et al.  Anti-Osteoporotic Effects of Kukoamine B Isolated from Lycii Radicis Cortex Extract on Osteoblast and Osteoclast Cells and Ovariectomized Osteoporosis Model Mice , 2019, International journal of molecular sciences.

[69]  S. Ferguson,et al.  Systemic sclerostin antibody treatment increases osseointegration and biomechanical competence of zoledronic-acid-coated dental implants in a rat osteoporosis model. , 2019, European cells & materials.

[70]  Shun-Fu Chang,et al.  Zoledronate induces cell cycle arrest and differentiation by upregulating p21 in mouse MC3T3-E1 preosteoblasts , 2019, International journal of medical sciences.

[71]  Anna Olchowy,et al.  Modifications of Polymeric Membranes Used in Guided Tissue and Bone Regeneration , 2019, Polymers.

[72]  C. Shih,et al.  Improving Two-Step Prepared CH3NH3PbI3 Perovskite Solar Cells by Co-Doping Potassium Halide and Water in PbI2 Layer , 2019, Nanomaterials.

[73]  Xiaoqing Song,et al.  Preparation and characterization of general-purpose gelatin-based co-loading flavonoids nano-core structure , 2019, Scientific Reports.

[74]  V. Zeleňák,et al.  A Study of 5-Fluorouracil Desorption from Mesoporous Silica by RP-UHPLC , 2019, Molecules.

[75]  H. J. Kim,et al.  Zoledronate Enhances Osteocyte-Mediated Osteoclast Differentiation by IL-6/RANKL Axis , 2019, International journal of molecular sciences.

[76]  Chao He,et al.  Heparin-based and heparin-inspired hydrogels: size-effect, gelation and biomedical applications. , 2019, Journal of materials chemistry. B.

[77]  R. Latorre,et al.  Zoledronic Acid Modulation of TRPV1 Channel Currents in Osteoblast Cell Line and Native Rat and Mouse Bone Marrow-Derived Osteoblasts: Cell Proliferation and Mineralization Effect , 2019, Cancers.

[78]  Yong Han,et al.  Regulation of osteogenesis and osteoclastogenesis by zoledronic acid loaded on biodegradable magnesium-strontium alloy , 2019, Scientific Reports.

[79]  Xiaohong Wu,et al.  Electrosprayed naringin-loaded microsphere/SAIB hybrid depots enhance bone formation in a mouse calvarial defect model , 2019, Drug delivery.

[80]  C. Rungsiyakull,et al.  Comparative study of stress characteristics in surrounding bone during insertion of dental implants of three different thread designs: A three‐dimensional dynamic finite element study , 2018, Clinical and experimental dental research.

[81]  Xuesi Chen,et al.  Osteoinductive Agents-Incorporated Three-Dimensional Biphasic Polymer Scaffold for Synergistic Bone Regeneration. , 2018, ACS biomaterials science & engineering.

[82]  J. Jansen,et al.  Alendronate release from calcium phosphate cement for bone regeneration in osteoporotic conditions , 2018, Scientific Reports.

[83]  Jie Tian,et al.  Advanced nanomaterials targeting hypoxia to enhance radiotherapy , 2018, International journal of nanomedicine.

[84]  Q. Wan,et al.  Graphene Family Materials in Bone Tissue Regeneration: Perspectives and Challenges , 2018, Nanoscale Research Letters.

[85]  S. Vijayakumar,et al.  Microwave assisted green synthesis of Hydroxyapatite nanorods using Moringa oleifera flower extract and its antimicrobial applications , 2018, International journal of veterinary science and medicine.

[86]  Jun Hee Lee,et al.  Investigation of the mechanism of chromium removal in (3-aminopropyl)trimethoxysilane functionalized mesoporous silica , 2018, Scientific Reports.

[87]  Zubing Li,et al.  PDGF-BB promotes the differentiation and proliferation of MC3T3-E1 cells through the Src/JAK2 signaling pathway , 2018, Molecular medicine reports.

[88]  K. Aktories,et al.  Involvement of Osteocytes in the Action of Pasteurella multocida Toxin , 2018, Toxins.

[89]  S. Dong,et al.  Chemical Self-Assembly of Multifunctional Hydroxyapatite with a Coral-like Nanostructure for Osteoporotic Bone Reconstruction. , 2018, ACS applied materials & interfaces.

[90]  T. Tkaczyk,et al.  3D printed fiber optic faceplates by custom controlled fused deposition modeling. , 2018, Optics express.

[91]  Eun-Cheol Kim,et al.  Bisphosphonates hinder osteoblastic/osteoclastic differentiation in the maxillary sinus mucosa-derived stem cells , 2018, Clinical Oral Investigations.

[92]  Max A. Horlbeck,et al.  Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates , 2018, eLife.

[93]  A. Caneschi,et al.  Type I Collagen and Strontium-Containing Mesoporous Glass Particles as Hybrid Material for 3D Printing of Bone-Like Materials , 2018, Materials.

[94]  Deliang Zeng,et al.  Alendronate delivery on amino modified mesoporous bioactive glass scaffolds to enhance bone regeneration in osteoporosis rats , 2018, Artificial cells, nanomedicine, and biotechnology.

[95]  T. Palaga,et al.  Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway , 2018, Scientific Reports.

[96]  B. Park,et al.  Cytoprotective effect of flavonoid‐induced autophagy on bisphosphonate mediated cell death in osteoblast , 2018, Journal of cellular biochemistry.

[97]  Ashley A. Vu,et al.  Effects of polycaprolactone on alendronate drug release from Mg-doped hydroxyapatite coating on titanium. , 2018, Materials science & engineering. C, Materials for biological applications.

[98]  O. García-Martínez,et al.  Bisphosphonate Modulation of the Gene Expression of Different Markers Involved in Osteoblast Physiology: Possible Implications in Bisphosphonate-Related Osteonecrosis of the Jaw , 2018, International journal of medical sciences.

[99]  Y. H. Kim,et al.  Antioxidant and Anti-Osteoporosis Activities of Chemical Constituents of the Stems of Zanthoxylum piperitum , 2018, Molecules.

[100]  Shuping Peng,et al.  Bone biomaterials and interactions with stem cells , 2017, Bone Research.

[101]  Yu Zhang,et al.  Simple 3,4-Dihydroxy-L-Phenylalanine Surface Modification Enhances Titanium Implant Osseointegration in Ovariectomized Rats , 2017, Scientific Reports.

[102]  Jun Shi,et al.  Effect of titanium implants with strontium incorporation on bone apposition in animal models: A systematic review and meta-analysis , 2017, Scientific Reports.

[103]  Yu Chen,et al.  Tumor-selective catalytic nanomedicine by nanocatalyst delivery , 2017, Nature Communications.

[104]  L. Bonewald,et al.  Osteocytes Acidify Their Microenvironment in Response to PTHrP In Vitro and in Lactating Mice In Vivo , 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[105]  H. Okamura,et al.  Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug , 2017, Scientific Reports.

[106]  Yun Chen,et al.  A Quasi-direct LC-MS/MS-based Targeted Proteomics Approach for miRNA Quantification via a Covalently Immobilized DNA-peptide Probe , 2017, Scientific Reports.

[107]  L. Xia,et al.  Evaluation of Osteogenesis and Angiogenesis of Icariin in Local Controlled Release and Systemic Delivery for Calvarial Defect in Ovariectomized Rats , 2017, Scientific Reports.

[108]  Chen Jiang,et al.  Biomacromolecules as carriers in drug delivery and tissue engineering , 2017, Acta pharmaceutica Sinica. B.

[109]  Yi Zhao,et al.  99Tc-MDP-induced human osteoblast proliferation, differentiation and expression of osteoprotegerin , 2017, Molecular medicine reports.

[110]  Muhammad Sohail Zafar,et al.  Bisphosphonate releasing dental implant surface coatings and osseointegration: A systematic review , 2017, Journal of Taibah University Medical Sciences.

[111]  F. Ren,et al.  Bio-inspired immobilization of strontium substituted hydroxyapatite nanocrystals and alendronate on the surface of AZ31 magnesium alloy for osteoporotic fracture repair , 2017 .

[112]  Surong Mei,et al.  Environmentally friendly chitosan/PEI-grafted magnetic gelatin for the highly effective removal of heavy metals from drinking water , 2017, Scientific Reports.

[113]  L. Xing,et al.  Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid , 2017, Scientific Reports.

[114]  Jie Du,et al.  Pretreatment with Bisphosphonate Enhances Osteogenesis of Bone Marrow Mesenchymal Stem Cells. , 2017, Stem cells and development.

[115]  Muhammad Sohail Zafar,et al.  Effect of bisphosphonates on root resorption after tooth replantation – a systematic review , 2017, Dental traumatology : official publication of International Association for Dental Traumatology.

[116]  J. Nedelec,et al.  First-Row Transition Metal Doping in Calcium Phosphate Bioceramics: A Detailed Crystallographic Study , 2017, Materials.

[117]  Qiang Zhang,et al.  Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix , 2017, Drug delivery.

[118]  P. Aspenberg,et al.  Randomised trial of bisphosphonate-coated dental implants: Radiographic follow-up after five years of loading. , 2016, International journal of oral and maxillofacial surgery.

[119]  Yan Hu,et al.  Regulation of local bone remodeling mediated by hybrid multilayer coating embedded with hyaluronan-alendronate/BMP-2 nanoparticles on Ti6Al7Nb implants. , 2016, Journal of materials chemistry. B.

[120]  J. Chakraborty,et al.  Role of a nitrogenous bisphosphonate (local delivery) incorporated vitreous coating (with/without polymer) on surgical grade SS316L implant material to improve fixation at the damaged tissue site , 2016 .

[121]  S. Seneff,et al.  Is GERD a Factor in Osteonecrosis of the Jaw? Evidence of Pathology Linked to G6PD Deficiency and Sulfomucins , 2016, Disease markers.

[122]  S. Dry,et al.  Rheumatoid Arthritis Exacerbates the Severity of Osteonecrosis of the Jaws (ONJ) in Mice. A Randomized, Prospective, Controlled Animal Study , 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[123]  R. Roeder,et al.  Targeted delivery to bone and mineral deposits using bisphosphonate ligands. , 2016, Advanced drug delivery reviews.

[124]  Sung Eun Kim,et al.  Heparin-immobilized hydroxyapatite nanoparticles as a lactoferrin delivery system for improving osteogenic differentiation of adipose-derived stem cells , 2016, Biomedical materials.

[125]  J. Bielecki,et al.  The effect of alendronate on biomineralization at the bone/implant interface. , 2016, Journal of biomedical materials research. Part A.

[126]  A. Gebert,et al.  Polyelectrolyte Complex Based Interfacial Drug Delivery System with Controlled Loading and Improved Release Performance for Bone Therapeutics , 2016, Nanomaterials.

[127]  L. Qiu,et al.  Preparation and Biological Evaluation of Two Novel Platinum(II) Complexes Based on the Ligands of Dipicolyamine Bisphosphonate Esters , 2016, Molecules.

[128]  Yan Hu,et al.  Alendronate-loaded hydroxyapatite-TiO2 nanotubes for improved bone formation in osteoporotic rabbits. , 2016, Journal of materials chemistry. B.

[129]  A. Qin,et al.  Structural simulation of adenosine phosphate via plumbagin and zoledronic acid competitively targets JNK/Erk to synergistically attenuate osteoclastogenesis in a breast cancer model , 2016, Cell Death and Disease.

[130]  Chun Gwon Park,et al.  Bioabsorbable bone plates enabled with local, sustained delivery of alendronate for bone regeneration. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[131]  Juan Pablo Couso,et al.  Discovery and characterization of smORF-encoded bioactive polypeptides. , 2015, Nature chemical biology.

[132]  R. Pereira,et al.  Effects of the long-term administration of alendronate on the mechanical properties of the basal bone and on osseointegration. , 2015, Clinical oral implants research.

[133]  Xin Huang,et al.  Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitro , 2015, Molecular medicine reports.

[134]  R. J. McCoy,et al.  The effect of bisphosphonate treatment on the biochemical and cellular events during bone remodelling in response to microinjury stimulation. , 2015, European cells & materials.

[135]  Junfeng Zhang,et al.  Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis , 2015, Autophagy.

[136]  Sung‐Wook Choi,et al.  Fabrication of a BMP-2-immobilized porous microsphere modified by heparin for bone tissue engineering. , 2015, Colloids and surfaces. B, Biointerfaces.

[137]  C. Haynes,et al.  In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)3 and La(XT), for the treatment of bone resorption disorders† †Electronic supplementary information (ESI) available: Speciation diagrams for metal–ligand complexes (Fig. S1 and S3), ITC analysis of H5XT-hydroxyapatite t , 2015, Chemical science.

[138]  Jazmín I González Ocampo,et al.  Porous bodies of hydroxyapatite produced by a combination of the gel-casting and polymer sponge methods , 2015, Journal of advanced research.

[139]  Hae-Ryong Song,et al.  Alendronate-Eluting Biphasic Calcium Phosphate (BCP) Scaffolds Stimulate Osteogenic Differentiation , 2015, BioMed research international.

[140]  I. Mihailescu,et al.  Strontium and zoledronate hydroxyapatites graded composite coatings for bone prostheses. , 2015, Journal of colloid and interface science.

[141]  A. Pabst,et al.  Bisphosphonates inhibit cell functions of HUVECs, fibroblasts and osteogenic cells via inhibition of protein geranylgeranylation , 2015, Clinical Oral Investigations.

[142]  Rong Zeng,et al.  Effectiveness of combined salmon calcitonin and aspirin therapy for osteoporosis in ovariectomized rats , 2015, Molecular medicine reports.

[143]  P. Pandolfi,et al.  A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells. , 2015, Cancer discovery.

[144]  J. Jansen,et al.  Hydroxyapatite nanocrystals functionalized with alendronate as bioactive components for bone implant coatings to decrease osteoclastic activity , 2015 .

[145]  P. Tengvall,et al.  Ex vivo alendronate localization at the mesoporous titania implant/bone interface , 2015, Journal of Materials Science: Materials in Medicine.

[146]  Y. Jiang,et al.  Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions , 2014, Cell Death and Disease.

[147]  Y. Soh,et al.  Evaluation of Osseointegration around Tibial Implants in Rats by Ibandronate-Treated Nanotubular Ti-32Nb-5Zr Alloy , 2014, Biomolecules & therapeutics.

[148]  Sung‐Wook Choi,et al.  Effect of lactoferrin-impregnated porous poly(lactide-co-glycolide) (PLGA) microspheres on osteogenic differentiation of rabbit adipose-derived stem cells (rADSCs). , 2014, Colloids and surfaces. B, Biointerfaces.

[149]  L. Duong,et al.  Inhibition of bone resorption by the cathepsin K inhibitor odanacatib is fully reversible. , 2014, Bone.

[150]  Shixin Chang,et al.  Influence of early zoledronic acid administration on bone marrow fat in ovariectomized rats. , 2014, Endocrinology.

[151]  S. Both,et al.  Synergistic effects of bisphosphonate and calcium phosphate nanoparticles on peri-implant bone responses in osteoporotic rats. , 2014, Biomaterials.

[152]  Susmita Bose,et al.  Polycaprolactone-Coated 3D Printed Tricalcium Phosphate Scaffolds for Bone Tissue Engineering: In Vitro Alendronate Release Behavior and Local Delivery Effect on In Vivo Osteogenesis , 2014, ACS applied materials & interfaces.

[153]  J. Jacobs,et al.  The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines , 2014, Mediators of inflammation.

[154]  Yufang Zhu,et al.  Mesoporous silica nanoparticles/hydroxyapatite composite coated implants to locally inhibit osteoclastic activity. , 2014, ACS applied materials & interfaces.

[155]  P. Procter,et al.  Early tissue responses to zoledronate, locally delivered by bone screw, into a compromised cancellous bone site: a pilot study , 2014, BMC Musculoskeletal Disorders.

[156]  T. narayanan,et al.  Strategies to improve the corrosion resistance of microarc oxidation (MAO) coated magnesium alloys for degradable implants: Prospects and challenges , 2014 .

[157]  J. A. Pura,et al.  Local Alendronic Acid Elution Increases Net Periimplant Bone Formation: A Micro-CT Analysis , 2014, Clinical orthopaedics and related research.

[158]  L. Visai,et al.  Preparation and Characterization of an Advanced Medical Device for Bone Regeneration , 2014, AAPS PharmSciTech.

[159]  Hae-Ryong Song,et al.  Osteogenesis induction of periodontal ligament cells onto bone morphogenic protein-2 immobilized PCL fibers. , 2014, Carbohydrate polymers.

[160]  Hae-Ryong Song,et al.  The effect of titanium with heparin/BMP-2 complex for improving osteoblast activity. , 2013, Carbohydrate polymers.

[161]  G. Georgiou,et al.  Hydroxyapatite, fluor-hydroxyapatite and fluorapatite produced via the sol–gel method: dissolution behaviour and biological properties after crystallisation , 2013, Journal of Materials Science: Materials in Medicine.

[162]  C. Cowell,et al.  Intravenous Zoledronic Acid Given Every 6 Months in Childhood Osteoporosis , 2013, Hormone Research in Paediatrics.

[163]  Yoshiya Tanaka,et al.  Dopamine D2-like receptor signaling suppresses human osteoclastogenesis. , 2013, Bone.

[164]  S. Bose,et al.  Lovastatin release from polycaprolactone coated β-tricalcium phosphate: effects of pH, concentration and drug-polymer interactions. , 2013, Materials science & engineering. C, Materials for biological applications.

[165]  P. Tengvall,et al.  Raloxifene and alendronate containing thin mesoporous titanium oxide films improve implant fixation to bone. , 2013, Acta biomaterialia.

[166]  S. Toksvig-Larsen,et al.  Bisphosphonate-coated external fixation pins appear similar to hydroxyapatite-coated pins in the tibial metaphysis and to uncoated pins in the shaft , 2013, Acta orthopaedica.

[167]  Jean-Christophe Leroux,et al.  Biomedical applications of bisphosphonates. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[168]  K. Neoh,et al.  An in vitro assessment of fibroblast and osteoblast response to alendronate-modified titanium and the potential for decreasing fibrous encapsulation. , 2013, Tissue engineering. Part A.

[169]  S. Bhaduri,et al.  Deposition of PLA/CDHA composite coating via electrospraying , 2013, Journal of biomaterials science. Polymer edition.

[170]  Di Chen,et al.  Overexpression of H1 calponin in osteoblast lineage cells leads to a decrease in bone mass by disrupting osteoblast function and promoting osteoclast formation , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[171]  P. Procter,et al.  Bone substitute materials delivering zoledronic acid: Physicochemical characterization, drug load, and release properties , 2013, Journal of biomaterials applications.

[172]  Y. Li,et al.  Promotion of peri-implant bone healing by systemically administered parathyroid hormone (1-34) and zoledronic acid adsorbed onto the implant surface , 2013, Osteoporosis International.

[173]  G. Schmidmaier,et al.  Effect of β-tricalcium phosphate coated with zoledronic acid on human osteoblasts and human osteoclasts in vitro , 2013, Journal of biomaterials applications.

[174]  M. Jia,et al.  Potential Antiosteoporotic Agents from Plants: A Comprehensive Review , 2012, Evidence-based complementary and alternative medicine : eCAM.

[175]  Zhongyong Fan,et al.  Degradation and osteogenic potential of a novel poly(lactic acid)/nano-sized β-tricalcium phosphate scaffold , 2012, International journal of nanomedicine.

[176]  D. Kimmel,et al.  Oncologic doses of zoledronic acid induce osteonecrosis of the jaw‐like lesions in rice rats (Oryzomys palustris) with periodontitis , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[177]  R. Weinstein.  Glucocorticoid-induced osteoporosis and osteonecrosis. , 2012, Endocrinology and metabolism clinics of North America.

[178]  T. Cheng,et al.  Up-regulated expression of MIF by interfacial membrane fibroblasts and macrophages around aseptically loosened implants. , 2012, The Journal of surgical research.

[179]  P. Zhen,et al.  Peri-implant and systemic effects of high-/low-affinity bisphosphonate-hydroxyapatite composite coatings in a rabbit model with peri-implant high bone turnover , 2012, BMC Musculoskeletal Disorders.

[180]  A. Boccaccini,et al.  Bisphosphonate-based strategies for bone tissue engineering and orthopedic implants. , 2012, Tissue engineering. Part B, Reviews.

[181]  Pentti Tengvall,et al.  A bisphosphonate-coating improves the fixation of metal implants in human bone. A randomized trial of dental implants , 2012, BDJ.

[182]  N. Haas,et al.  Effect of local zoledronate on implant osseointegration in a rat model , 2012, BMC Musculoskeletal Disorders.

[183]  J. Marc,et al.  The relationship between osteoclastogenic and anti-osteoclastogenic pro-inflammatory cytokines differs in human osteoporotic and osteoarthritic bone tissues , 2012, Journal of Biomedical Science.

[184]  P. Tengvall,et al.  Local bisphosphonate release versus hydroxyapatite coating for stainless steel screw fixation in rat tibiae , 2012, Journal of Materials Science: Materials in Medicine.

[185]  L. Plotkin,et al.  Role of connexin 43 in the mechanism of action of alendronate: dissociation of anti-apoptotic and proliferative signaling pathways. , 2012, Archives of biochemistry and biophysics.

[186]  S. Bhaduri,et al.  Biomimetic coating of bisphosphonate incorporated CDHA on Ti6Al4V , 2012, Journal of Materials Science: Materials in Medicine.

[187]  T. Ahmed,et al.  Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence , 2012, Respiratory Research.

[188]  D. Pioletti,et al.  In vivo assessment of local effects after application of bone screws delivering bisphosphonates into a compromised cancellous bone site. , 2011, Clinical biomechanics.

[189]  Min Soo Bae,et al.  Effect of heparin and alendronate coating on titanium surfaces on inhibition of osteoclast and enhancement of osteoblast function. , 2011, Biochemical and biophysical research communications.

[190]  Y. Soh,et al.  Effect of bisphosphonates on anodized and heat-treated titanium surfaces: an animal experimental study. , 2011, Journal of periodontology.

[191]  L. Plotkin,et al.  Novel actions of bisphosphonates in bone: preservation of osteoblast and osteocyte viability. , 2011, Bone.

[192]  N. D’Silva,et al.  Bisphosphonates Inhibit Expression of p63 by Oral Keratinocytes , 2011, Journal of dental research.

[193]  T. Coradin,et al.  Nanoporous surface of organofunctionalized hydroxyapatite fabricated from natural phosphate rock , 2010 .

[194]  Gwo‐Jaw Wang,et al.  The effect of the local delivery of alendronate on human adipose-derived stem cell-based bone regeneration. , 2010, Biomaterials.

[195]  P. Tengvall,et al.  Sol-gel derived titania coating with immobilized bisphosphonate enhances screw fixation in rat tibia. , 2010, Journal of biomedical materials research. Part A.

[196]  S. Seino,et al.  Alendronate induces mineralization in mouse osteoblastic MC3T3-E1 cells: regulation of mineralization-related genes. , 2010, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

[197]  T. Jakobsen,et al.  The Effect of Soaking Allograft in Bisphosphonate: A Pilot Dose-response Study , 2010, Clinical orthopaedics and related research.

[198]  I. Mihailescu,et al.  Biofunctional alendronate-Hydroxyapatite thin films deposited by Matrix Assisted Pulsed Laser Evaporation. , 2009, Biomaterials.

[199]  D. Chappard,et al.  In vitro kinetic study of growth and mineralization of osteoblast-like cells (Saos-2) on titanium surface coated with a RGD functionalized bisphosphonate. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.

[200]  X. Liu,et al.  The effect of surface immobilized bisphosphonates on the fixation of hydroxyapatite-coated titanium implants in ovariectomized rats. , 2009, Biomaterials.

[201]  P. Aspenberg.  Bisphosphonates and implants , 2009, Acta orthopaedica.

[202]  M. Vallet‐Regí,et al.  Functionalization degree of SBA-15 as key factor to modulate sodium alendronate dosage , 2008 .

[203]  Samuel K. Cho,et al.  Enhancement of periprosthetic bone quality with topical hydroxyapatite-bisphosphonate composite. , 2008, The Journal of bone and joint surgery. American volume.

[204]  Y. Miao,et al.  Stimulation of osteogenic differentiation and inhibition of adipogenic differentiation in bone marrow stromal cells by alendronate via ERK and JNK activation. , 2008, Bone.

[205]  P. Tengvall,et al.  Bisphosphonate coating on titanium screws increases mechanical fixation in rat tibia after two weeks. , 2008, Journal of biomedical materials research. Part A.

[206]  B. Masri,et al.  Enhanced gap filling and osteoconduction associated with alendronate-calcium phosphate-coated porous tantalum. , 2008, The Journal of bone and joint surgery. American volume.

[207]  P. Tengvall,et al.  Stainless steel screws coated with bisphosphonates gave stronger fixation and more surrounding bone. Histomorphometry in rats. , 2008, Bone.

[208]  N. Watts,et al.  Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy , 2008, Osteoporosis International.

[209]  G. Schmidmaier,et al.  Bisphosphonates incorporated in a poly(D,L-lactide) implant coating inhibit osteoclast like cells in vitro. , 2007, Journal of biomedical materials research. Part A.

[210]  G. Duque,et al.  Alendronate Has an Anabolic Effect on Bone Through the Differentiation of Mesenchymal Stem Cells , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[211]  María Vallet-Regí,et al.  Confinement and controlled release of bisphosphonates on ordered mesoporous silica-based materials. , 2006, Journal of the American Chemical Society.

[212]  G. H. Nancollas,et al.  Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite. , 2006, Bone.

[213]  M. Rogers,et al.  Cytosolic Entry of Bisphosphonate Drugs Requires Acidification of Vesicles after Fluid-Phase Endocytosis , 2006, Molecular Pharmacology.

[214]  I. Martin,et al.  Effects of bisphosphonates on proliferation and osteoblast differentiation of human bone marrow stromal cells. , 2005, Biomaterials.

[215]  Michael Tanzer,et al.  THE OTTO AUFRANC AWARD: Bone Augmentation around and within Porous Implants by Local Bisphosphonate Elution , 2005, Clinical orthopaedics and related research.

[216]  Lynne E Bilston,et al.  A single systemic dose of pamidronate improves bone mineral content and accelerates restoration of strength in a rat model of fracture repair , 2005, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[217]  H. Rubash,et al.  Osteoblast proliferation and maturation by bisphosphonates. , 2004, Biomaterials.

[218]  P. Tengvall,et al.  Surface immobilized bisphosphonate improves stainless-steel screw fixation in rats. , 2004, Biomaterials.

[219]  D. P. Cohen,et al.  Anti‐Osteoporotic Medications: Traditional and Nontraditional , 2003, Clinical obstetrics and gynecology.

[220]  P. Aspenberg,et al.  Impact of a zoledronate coating on early post‐surgical implant stability and marginal bone resorption in the maxilla—A split‐mouth randomized clinical trial , 2019, Clinical oral implants research.

[221]  Jia Pei,et al.  Dual modulation of bone formation and resorption with zoledronic acid-loaded biodegradable magnesium alloy implants improves osteoporotic fracture healing: An in vitro and in vivo study. , 2018, Acta biomaterialia.

[222]  Yan Hu,et al.  Sustained raloxifene release from hyaluronan-alendronate-functionalized titanium nanotube arrays capable of enhancing osseointegration in osteoporotic rabbits. , 2018, Materials science & engineering. C, Materials for biological applications.

[223]  K. Neoh,et al.  Bifunctional coating based on carboxymethyl chitosan with stable conjugated alkaline phosphatase for inhibiting bacterial adhesion and promoting osteogenic differentiation on titanium , 2016 .

[224]  Naveid A Ali,et al.  Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer. , 2015, Cancer discovery.

[225]  P. Ducheyne,et al.  Sol-gel silica controlled release thin films for the inhibition of methicillin-resistant Staphylococcus aureus. , 2014, Biomaterials.

[226]  Jinyu Zhu,et al.  The inhibitory effect of alendronate-hydroxyapatite composite coating on wear debris-induced peri-implant high bone turnover. , 2013, The Journal of surgical research.

[227]  R. Müller,et al.  Local delivery of bisphosphonate from coated orthopedic implants increases implants mechanical stability in osteoporotic rats. , 2006, Journal of biomedical materials research. Part A.

[228]  P. Zambelli,et al.  Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration. , 2005, Bone.