LOSS OF SPROUTY GENE FUNCTION LEADS TO DENTAL ANOMALIES BY RENDERING DENTAL TISSUES HYPERSENSITIVE TO FGF SIGNALING

LOSS OF SPROUTY GENE FUNCTION LEADS TO DENTAL ANOMALIES BY RENDERING DENTAL TISSUES HYPERSENSITIVE TO FGF SIGNALING Ophir Klein, David Lyons, Renata Peterkova, Miroslav Peterka, Herve Lesot, Guive Balooch, Jukka Jernvall, Gail Martin Departments of Pediatrics; Anatomy; Biomaterials, University of California, San Francisco, CA, USA; Department of Teratology, Institute of Experimental Medicine, Prague, Czech Republic; INSERM and University of Louis Pasteur, Strasbourg, France; Institute of Biotechnology, University of Helsinki, Finland.