Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality
暂无分享,去创建一个
[1] S. Rankin,et al. CXCR4, the master regulator of neutrophil trafficking in homeostasis and disease , 2018, European journal of clinical investigation.
[2] L. Brammer,et al. Systematic Assessment of Multiple Routine and Near Real‐Time Indicators to Classify the Severity of Influenza Seasons and Pandemics in the United States, 2003‐2004 Through 2015‐2016 , 2018, American journal of epidemiology.
[3] C. Yabe-Nishimura,et al. Augmented neutrophil extracellular traps formation promotes atherosclerosis development in socially defeated apoE-/- mice. , 2018, Biochemical and biophysical research communications.
[4] V. Papayannopoulos. Neutrophil extracellular traps in immunity and disease , 2017, Nature Reviews Immunology.
[5] B. Moore,et al. IL-17 in the lung: the good, the bad, and the ugly. , 2018, American journal of physiology. Lung cellular and molecular physiology.
[6] M. Birrell,et al. Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection , 2017, Thorax.
[7] N. Kaminski,et al. Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice , 2017, The Journal of Immunology.
[8] A. Günther,et al. Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo , 2017, European Respiratory Journal.
[9] Colleen B. Jonsson,et al. A Role for Neutrophils in Viral Respiratory Disease , 2017, Front. Immunol..
[10] M. Surette,et al. Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction , 2017, Cell host & microbe.
[11] J. Kirkland,et al. Cellular Senescence: A Translational Perspective , 2017, EBioMedicine.
[12] T. Xiao,et al. Innate immunity and inflammation , 2016, Cellular & Molecular Immunology.
[13] M. Manz,et al. Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment , 2016, Front. Immunol..
[14] Janet S. Lee,et al. IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae. , 2016, Cell host & microbe.
[15] Derek W. Gilroy,et al. Resolution of inflammation: a new therapeutic frontier , 2016, Nature Reviews Drug Discovery.
[16] L. Haynes,et al. Age-related impairment of humoral response to influenza is associated with changes in antigen specific T follicular helper cell responses , 2016, Scientific Reports.
[17] Ruth R. Montgomery,et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease , 2016, Science.
[18] G. Kuchel,et al. T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines , 2016, Front. Immunol..
[19] T. van der Poll,et al. The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia , 2015, Gut.
[20] Richard J. Miller,et al. Neutrophil trails guide influenza-specific CD8+ T cells in the airways , 2015, Science.
[21] Haitao Guo,et al. Inflammasomes: mechanism of action, role in disease, and therapeutics , 2015, Nature Medicine.
[22] N. LeBrasseur,et al. Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity , 2015, Diabetes.
[23] M. Maes,et al. Measurement of Apoptotic and Necrotic Cell Death in Primary Hepatocyte Cultures. , 2015, Methods in molecular biology.
[24] M. Cassatella,et al. Neutrophil-Derived Cytokines: Facts Beyond Expression , 2014, Front. Immunol..
[25] Elizabeth Sapey,et al. Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals , 2014, Aging cell.
[26] T. Mayadas,et al. The multifaceted functions of neutrophils. , 2014, Annual review of pathology.
[27] T. Hussell,et al. Alveolar macrophages: plasticity in a tissue-specific context , 2014, Nature Reviews Immunology.
[28] R. Stockley,et al. PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly : toward targeted treatments for immunosenescence , 2013 .
[29] Ruth R. Montgomery,et al. Age-dependent dysregulation of innate immunity , 2013, Nature Reviews Immunology.
[30] Frederick Klauschen,et al. A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection , 2013, Cell.
[31] D. Bartlett,et al. Understanding how we age: insights into inflammaging , 2013, Longevity & healthspan.
[32] J. Campisi,et al. Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. , 2013, The Journal of clinical investigation.
[33] M. Sykes,et al. Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. , 2013, Immunity.
[34] D. Sinderen,et al. Gut microbiota composition correlates with diet and health in the elderly , 2012, Nature.
[35] R. Jaramillo,et al. Impaired NLRP3 Inflammasome Function in Elderly Mice during Influenza Infection Is Rescued by Treatment with Nigericin , 2012, The Journal of Immunology.
[36] E. Gardner,et al. Natural killer cell function is altered during the primary response of aged mice to influenza infection , 2011, Mechanisms of Ageing and Development.
[37] D. Murasko,et al. CD8 T cell responses to influenza virus infection in aged mice , 2011, Ageing Research Reviews.
[38] C. Weaver,et al. Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection , 2011, Infection and Immunity.
[39] N. Van Rooijen,et al. Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis , 2011, The American Journal of Pathology.
[40] D. Murasko,et al. Expansion of regulatory T cells in aged mice following influenza infection , 2011, Mechanisms of Ageing and Development.
[41] A. Iwasaki,et al. Microbiota regulates immune defense against respiratory tract influenza A virus infection , 2011, Proceedings of the National Academy of Sciences.
[42] P. Kubes,et al. Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation , 2010, Science.
[43] S. Rankin,et al. Neutrophil kinetics in health and disease , 2010, Trends in immunology.
[44] A. Charlett,et al. Pandemic Influenza A (H1N1) 2009 and mortality in the United Kingdom: risk factors for death, April 2009 to March 2010. , 2010, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.
[45] Leo A. B. Joosten,et al. IL-1β Processing in Host Defense: Beyond the Inflammasomes , 2010, PLoS pathogens.
[46] Jeffrey N. Weiser,et al. Recognition of Peptidoglycan from the Microbiota by Nod1 Enhances Systemic Innate Immunity , 2010, Nature Medicine.
[47] Steven L. Kunkel,et al. Critical Role of IL-1 Receptor-Associated Kinase-M in Regulating Chemokine-Dependent Deleterious Inflammation in Murine Influenza Pneumonia , 2009, The Journal of Immunology.
[48] M. Tate,et al. Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection1 , 2009, The Journal of Immunology.
[49] M. Karin,et al. Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation. , 2009, Arthritis and rheumatism.
[50] J. Campisi,et al. Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo , 2009, Nature Protocols.
[51] T. Ross,et al. Impaired immune responses in the lungs of aged mice following influenza infection , 2009, Respiratory Research.
[52] J. Alcorn,et al. Critical Role of IL-17RA in Immunopathology of Influenza Infection , 2009, The Journal of Immunology.
[53] E. Kovacs,et al. Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors. , 2009, Trends in immunology.
[54] S. Rankin,et al. Neutrophil mobilization and clearance in the bone marrow , 2008, Immunology.
[55] M. Tate,et al. The role of neutrophils in the upper and lower respiratory tract during influenza virus infection of mice , 2008, Respiratory research.
[56] Arthur S Slutsky,et al. Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury , 2008, Cell.
[57] J. Raboud,et al. Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[58] Peter B. Dias,et al. CXCR2 is required for neutrophil recruitment to the lung during influenza virus infection, but is not essential for viral clearance. , 2007, Viral immunology.
[59] K. Brown,et al. Pulmonary Stromal-Derived Factor-1 Expression and Effect on Neutrophil Recruitment during Acute Lung Injury1 , 2007, The Journal of Immunology.
[60] Y. Iwakura,et al. The IL-23/IL-17 axis in inflammation. , 2006, The Journal of clinical investigation.
[61] R. Mason. Biology of alveolar type II cells , 2006, Respirology.
[62] R. Holman,et al. Trends in hospitalizations for pneumonia among persons aged 65 years or older in the United States, 1988-2002. , 2005, JAMA.
[63] O. Lesur,et al. Signal transduction and functional changes in neutrophils with aging , 2004, Aging cell.
[64] K. Malcolm,et al. Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis. , 2004, Blood.
[65] E. Chilvers,et al. The survival effect of TNF‐α in human neutrophils is mediated via NF‐κB‐dependent IL‐8 release , 2004 .
[66] Keiji Fukuda,et al. Mortality associated with influenza and respiratory syncytial virus in the United States. , 2003, JAMA.
[67] W. Hörl,et al. Effect of age on human neutrophil function , 2000, Journal of leukocyte biology.
[68] R. Strieter,et al. TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation. , 1995, Journal of immunology.
[69] C. Demangel,et al. Lactate dehydrogenase (LDH) activity of the number of dead cells in the medium of cultured eukaryotic cells as marker , 1992 .