The GOR Method for Predicting Secondary Structures in Proteins

The widely used term “secondary structure” implies that it is of value to consider the structure of a protein as organized hierarchically. “Hierarchic” relates to the idea that the structure can be considered on at least two levels; there are, in fact, three levels of interest here, namely, the covalent structure (primary), the structural organization of stereoregular regions as specific backbone conformations (secondary), and the way in which they are assembled in a three-dimensional conformation (tertiary structure) to make a protein. The recently introduced concept of “supersecondary” structure intermediate to secondary and tertiary levels describes the interactions between secondary structures in space. It should also be stated that the more recently recommended definition of secondary structure covers all backbone conformations, stereoirregular as well as stereoregular.

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