Virgin coconut oil attenuates lipopolysaccharide-induced depression-like behaviors: Integrating network pharmacology analysis and molecular mechanism evaluation
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Jia Li | Zirun Chen | Ying Wang | Zhaoting Lv | Jianliang Sun | Hui Wang | Yuan Lin | Qun Zhang | Yi Fan | Xiuchun Li | Xiwu Wang | Shuangda Miao | Yingwei Lu | Yuanyuan Fang | Xuyi Pan
[1] Yong Cheng,et al. Anti-depressant-like effects of rannasangpei and its active ingredient crocin-1 on chronic unpredictable mild stress mice , 2023, Frontiers in Pharmacology.
[2] A. Ornoy,et al. Animal Models of Depression: What Can They Teach Us about the Human Disease? , 2021, Diagnostics.
[3] Junjie Huang,et al. Scutellarin protects against lipopolysaccharide-induced behavioral deficits by inhibiting neuroinflammation and microglia activation in rats. , 2020, International immunopharmacology.
[4] LiJun Xu,et al. Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis , 2020, Molecular medicine.
[5] S. Jang,et al. Luteolin and Apigenin Attenuate LPS-Induced Astrocyte Activation and Cytokine Production by Targeting MAPK, STAT3, and NF-κB Signaling Pathways , 2020, Inflammation.
[6] Yong Cheng,et al. Exosomes from patients with major depression cause depressive-like behaviors in mice with involvement of miR-139-5p-regulated neurogenesis , 2020, Neuropsychopharmacology.
[7] M. M. López-Rodríguez,et al. The Impact of Coconut Oil and Epigallocatechin Gallate on the Levels of IL-6, Anxiety and Disability in Multiple Sclerosis Patients , 2020, Nutrients.
[8] L. Lao,et al. Potential link between the RagA-mTOR-p70S6K axis and depressive-behaviors during bacterial liposaccharide challenge , 2019, Journal of Neuroinflammation.
[9] Chuang Yang,et al. Crocin ameliorates chronic obstructive pulmonary disease-induced depression via PI3K/Akt mediated suppression of inflammation. , 2019, European journal of pharmacology.
[10] Xinmin Liu,et al. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus , 2019, Brain Research Bulletin.
[11] Manoj Kumar,et al. INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER’S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA , 2019, Alzheimer's & Dementia.
[12] Zhi-xiu Lin,et al. Isorhynchophylline exerts antidepressant‐like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK‐3β signaling pathway , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[13] Lijie Sun,et al. ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice , 2019, Neuroscience.
[14] S. Santos,et al. Virgin coconut oil is effective to treat metabolic and inflammatory dysfunction induced by high refined carbohydrate-containing diet in mice. , 2019, The Journal of nutritional biochemistry.
[15] Wen-jun Su,et al. Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus , 2018, Front. Cell. Neurosci..
[16] B. Alghamdi. Possible prophylactic anti-excitotoxic and anti-oxidant effects of virgin coconut oil on aluminium chloride-induced Alzheimer's in rat models. , 2018, Journal of integrative neuroscience.
[17] G. Dugo,et al. Chemical characterization of a variety of cold-pressed gourmet oils available on the Brazilian market. , 2018, Food research international.
[18] Z. Mari,et al. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease , 2018, Nature Medicine.
[19] P. Xie,et al. PI3K/AKT/JNK/p38 signalling pathway‐mediated neural apoptosis in the prefrontal cortex of mice is involved in the antidepressant‐like effect of pioglitazone , 2018, Clinical and experimental pharmacology & physiology.
[20] Wei Zhao,et al. Hippocampal mTOR signaling is required for the antidepressant effects of paroxetine , 2018, Neuropharmacology.
[21] Lewis C. Cantley,et al. The PI3K Pathway in Human Disease , 2017, Cell.
[22] A. Carvalho,et al. Peripheral cytokine and chemokine alterations in depression: a meta‐analysis of 82 studies , 2017, Acta psychiatrica Scandinavica.
[23] O. Wolkowitz,et al. Oxidative stress, inflammation and treatment response in major depression , 2017, Psychoneuroendocrinology.
[24] M. Ratheesh,et al. Anti-inflammatory and antioxidant effect of Kerabala: a value-added ayurvedic formulation from virgin coconut oil inhibits pathogenesis in adjuvant-induced arthritis , 2017, Inflammopharmacology.
[25] Shiping Ma,et al. Umbelliferone reverses depression-like behavior in chronic unpredictable mild stress-induced rats by attenuating neuronal apoptosis via regulating ROCK/Akt pathway , 2017, Behavioural Brain Research.
[26] Nur Syafiqah Rahim,et al. Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress , 2017, Pharmaceutical biology.
[27] M. Maes,et al. Depression in Cancer : the many biobehavioural pathways driving tumor progression , 2016 .
[28] O. Mors,et al. Inflammation in Depression and the Potential for Anti-Inflammatory Treatment , 2016, Current neuropharmacology.
[29] Xu Luo,et al. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane , 2016, Genes & development.
[30] G. Gevorkian,et al. LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals , 2016, Current neuropharmacology.
[31] J. Kiecolt-Glaser,et al. Inflammation: depression fans the flames and feasts on the heat. , 2015, The American journal of psychiatry.
[32] Alan A. Wilson,et al. Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes. , 2015, JAMA psychiatry.
[33] M. Kabbaj,et al. Epigenetic mechanisms underlying the role of brain-derived neurotrophic factor in depression and response to antidepressants , 2015, Journal of Experimental Biology.
[34] Kerri Smith,et al. Mental health: A world of depression , 2014, Nature.
[35] G. Turecki,et al. Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides , 2014, Brain, Behavior, and Immunity.
[36] G. Hu,et al. Female Early Adult Depression Results in Detrimental Impacts on the Behavioral Performance and Brain Development in Offspring , 2012, CNS neuroscience & therapeutics.
[37] J. Feldon,et al. Long-term effects of early life deprivation on brain glia in Fischer rats , 2007, Brain Research.
[38] J. Bauer,et al. NF‐κB modulates lipopolysaccharide‐induced microglial nerve growth factor expression , 1998 .
[39] Xiaoxin Yin,et al. Inhibition of activated astrocyte ameliorates lipopolysaccharide- induced depressive-like behaviors. , 2019, Journal of affective disorders.