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The objective of the study was to determine the effectiveness of advice from medical professionals to overweight men. One hundred participants were randomly assigned to treatment and control groups. Healthcare professionals gave advice to men in the treatment groups. At one-year follow-up, when analysed according to intention to treat, the treatment group reported significant weight loss compared with the control group (p < 0.05). Open-ended questionnaires were administered to ascertain the influencing factors. Successful weight loss depends of factors such as motivation, diet, and exercise.