In vivo effects of apoE and clusterin on amyloid-β metabolism and neuropathology
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[1] J. Morris,et al. Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage alzheimer’s disease , 2001, Journal of Molecular Neuroscience.
[2] D. Holtzman. Role of apoE/Aβ interactions in the pathogenesis of Alzheimer’s disease and cerebral amyloid angiopathy , 2001, Journal of Molecular Neuroscience.
[3] R. Demattos,et al. Apolipoprotein E dose-dependent modulation of β-amyloid deposition in a transgenic mouse model of Alzheimer’s disease , 2007, Journal of Molecular Neuroscience.
[4] Bruce J Aronow,et al. ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition Evidence that ApoE Regulates Extracellular Aβ Metabolism In Vivo , 2004, Neuron.
[5] D. Holtzman,et al. Apolipoprotein E Markedly Facilitates Age-Dependent Cerebral Amyloid Angiopathy and Spontaneous Hemorrhage in Amyloid Precursor Protein Transgenic Mice , 2003, The Journal of Neuroscience.
[6] J. Sanes,et al. PDAPP; YFP double transgenic mice: A tool to study amyloid‐β associated changes in axonal, dendritic, and synaptic structures , 2003, The Journal of comparative neurology.
[7] Bruce J Aronow,et al. Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[8] A. Fagan,et al. Human and Murine ApoE Markedly Alters Aβ Metabolism before and after Plaque Formation in a Mouse Model of Alzheimer's Disease , 2002, Neurobiology of Disease.
[9] Xianlin Han,et al. Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice , 2001, Neurochemistry International.
[10] M. J. Wade,et al. Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. , 2001, Archives of neurology.
[11] S. Younkin,et al. The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation , 2001, Nature Neuroscience.
[12] Y. Ihara,et al. Alzheimer β Amyloid Deposition Enhanced by ApoE ϵ4 Gene Precedes Neurofibrillary Pathology in the Frontal Association Cortex of Nondemented Senior Subjects , 2001 .
[13] A Rostagno,et al. Apolipoprotein J (clusterin) and Alzheimer's disease , 2000, Microscopy research and technique.
[14] S. Younkin,et al. Biochemical detection of Aβ isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer’s disease , 2000 .
[15] A. Fagan,et al. Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model , 2000, Annals of neurology.
[16] A. Fagan,et al. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[17] A. Roses,et al. Apolipoprotein E and Alzheimer's disease. , 1996, Annual review of neuroscience.
[18] S. Paul,et al. Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[19] B. Sommer,et al. Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[20] A. Fagan,et al. Unique Lipoproteins Secreted by Primary Astrocytes From Wild Type, apoE (−/−), and Human apoE Transgenic Mice* , 1999, The Journal of Biological Chemistry.
[21] A. Fagan,et al. Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease. , 1999, The Journal of clinical investigation.
[22] J. Morris,et al. Tangles and plaques in nondemented aging and “preclinical” Alzheimer's disease , 1999, Annals of neurology.
[23] T. Morgan,et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[24] D. Rader,et al. Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice. , 1998, The American journal of pathology.
[25] D. Holtzman,et al. Nascent Astrocyte Particles Differ from Lipoproteins in CSF , 1998, Journal of neurochemistry.
[26] S. Paul,et al. Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition , 1997, Nature Genetics.
[27] N. Maeda,et al. Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis* , 1997, The Journal of Biological Chemistry.
[28] S. Younkin,et al. Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice , 1996, Science.
[29] J. Morris,et al. Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease , 1996, The Journal of Neuroscience.
[30] C. Soto,et al. Apolipoprotein J and Alzheimer's amyloid beta solubility. , 1996, The Biochemical journal.
[31] E. Matsubara,et al. Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[32] W. V. Van Nostrand,et al. Enhanced pathologic properties of Dutch-type mutant amyloid beta-protein. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[33] Steven A. Johnson,et al. Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress , 1995, Experimental Neurology.
[34] B. Hyman,et al. Apolipoprotein E ϵ4 and cerebral hemorrhage associated with amyloid angiopathy , 1995 .
[35] D. Selkoe,et al. Co-expression of β-amyloid precursor protein (βAPP) and apolipoprotein E in cell culture: analysis of βAPP processing , 1995, Neurobiology of Disease.
[36] E. Matsubara,et al. Characterization of Apolipoprotein J-Alzheimer's Aβ Interaction (*) , 1995, The Journal of Biological Chemistry.
[37] T. Wisniewski,et al. Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E. , 1995, The Biochemical journal.
[38] L. Mucke,et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein , 1995, Nature.
[39] S. Wilton,et al. Apolipoprotein E and Alzheimer's disease , 1995 .
[40] T. Wisniewski,et al. Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta. , 1994, Biochemical and biophysical research communications.
[41] H. Brewer,et al. Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments , 1994, Nature.
[42] G. Getz,et al. Isoform-specific binding of apolipoprotein E to beta-amyloid. , 1994, The Journal of biological chemistry.
[43] A. Roses,et al. Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. , 1994, The Journal of clinical investigation.
[44] S. Younkin,et al. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. , 1994, Science.
[45] J. Ma,et al. Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments. , 1994, Nature.
[46] J. Haines,et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. , 1993, Science.
[47] T. Wisniewski,et al. The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex. , 1993, The Biochemical journal.
[48] M. Pericak-Vance,et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[49] C. Finch,et al. Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration , 1992, Trends in Neurosciences.
[50] B. Winblad,et al. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid , 1992, Nature Genetics.
[51] M. Pericak-Vance,et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease , 1991, Nature.
[52] Steven A. Johnson,et al. Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat , 1990, Neuron.
[53] I. Lieberburg,et al. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. , 1990, Science.
[54] G. Heinrich. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. , 1989, The New England journal of medicine.
[55] R. S. Williams,et al. A prospective study of Alzheimer disease in Down syndrome. , 1989, Archives of neurology.
[56] D. Selkoe,et al. Protein chemical and immunocytochemical studies of meningovascular β-amyloid protein in Alzheimer's disease and normal aging , 1988, Brain Research.
[57] H. Vinters. Cerebral amyloid angiopathy. A critical review. , 1987, Stroke.
[58] H. Wiśniewski,et al. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome , 1985, Annals of neurology.
[59] G. Vega,et al. Apolipoproteins in human cerebrospinal fluid. , 1979, Proceedings of the National Academy of Sciences of the United States of America.