A phase 2 trial of complete resection for stage IV melanoma

On the basis of retrospective experience at individual centers, it appears that patients with stage IV melanoma who undergo complete resection have a favorable outcome compared with patients with disseminated stage IV disease. The Southwest Oncology Group (SWOG) performed a prospective trial in patients with metastatic melanoma who were enrolled before complete resection of their metastatic disease and provided prospective outcomes in the cooperative group setting.

[1]  Jeffrey E Gershenwald,et al.  Final version of 2009 AJCC melanoma staging and classification. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2]  S. Martinez,et al.  A rational surgical approach to the treatment of distant melanoma metastases. , 2008, Cancer treatment reviews.

[3]  Jane Fridlyand,et al.  Improving Melanoma Classification by Integrating Genetic and Morphologic Features , 2008, PLoS medicine.

[4]  Donna Niedzwiecki,et al.  Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[5]  R. Elashoff,et al.  An international, randomized, phase III trial of bacillus Calmette-Guerin (BCG) plus allogeneic melanoma vaccine (MCV) or placebo after complete resection of melanoma metastatic to regional or distant sites , 2007 .

[6]  D. Ollila.  Complete metastasectomy in patients with stage IV metastatic melanoma. , 2006, The Lancet. Oncology.

[7]  R. Essner,et al.  The role of surgery in treatment of stage IV melanoma , 2006, Journal of surgical oncology.

[8]  V. Sondak,et al.  Surgical resection for stage IV melanoma: A Southwest Oncology Group trial (S9430). , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[9]  D. Coit,et al.  Role of surgery in patients with stage IV melanoma , 2004, Current opinion in oncology.

[10]  D. Morton,et al.  Prolonged survival after complete resection of disseminated melanoma and active immunotherapy with a therapeutic cancer vaccine. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[11]  D. Morton,et al.  Does Complete Resection of Melanoma Metastatic to Solid Intra-Abdominal Organs Improve Survival? , 2001, Annals of Surgical Oncology.

[12]  Martin F. Mihm,et al.  Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[13]  P. Rocmans,et al.  Lung metastases from melanoma: when is surgical treatment warranted? , 2000, British Journal of Cancer.

[14]  S. Soong,et al.  Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[15]  C. Begg,et al.  Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[16]  R. Fisher,et al.  High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[17]  D. Coit,et al.  Surgery for Melanoma Metastatic to the Gastrointestinal Tract , 1999, Annals of Surgical Oncology.

[18]  Morton Dl,et al.  Surgical resection as the treatment of choice for melanoma metastatic to the lung. , 1998 .

[19]  C. Garbe,et al.  Prolonged survival of 2 years or longer for patients with disseminated melanoma , 1997, Cancer.

[20]  D. Morton,et al.  Surgical resection for melanoma metastatic to the gastrointestinal tract. , 1996, Archives of surgery.

[21]  D. Morton,et al.  Prognostic factors in 1,521 melanoma patients with distant metastases. , 1995, Journal of the American College of Surgeons.

[22]  R. Benjamin,et al.  The natural history of resectable metastatic melanoma (Stage IVA Melanoma) , 1982, Cancer.

[23]  Ron Brookmeyer,et al.  A Confidence Interval for the Median Survival Time , 1982 .

[24]  E. Kaplan,et al.  Nonparametric Estimation from Incomplete Observations , 1958 .

[25]  V. Sondak,et al.  Treatment options for limited or symptomatic metastatic melanoma. , 2008, Cancer Control: Journal of the Moffitt Cancer Cente.

[26]  D. Harpole,et al.  Improved survival with pulmonary metastasectomy: an analysis of 1720 patients with pulmonary metastatic melanoma. , 2007, The Journal of thoracic and cardiovascular surgery.

[27]  J. Stockman,et al.  Distinct Sets of Genetic Alterations in Melanoma , 2007 .

[28]  D. Schadendorf,et al.  Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[29]  D.,et al.  Regression Models and Life-Tables , 2022 .