3-Kinase Activation IsRequired forInsulin Stimulation ofpp7OS6Kinase, DNA Synthesis, and Glucose Transporter Translocation

[1]  K Y Hui,et al.  A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). , 1994, The Journal of biological chemistry.

[2]  G. Crabtree,et al.  Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase , 1992, Nature.

[3]  G. Crabtree,et al.  Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases , 1992, Cell.

[4]  M. Birnbaum The insulin-sensitive glucose transporter. , 1992, International review of cytology.

[5]  A. Sorisky,et al.  "Thrombin" receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. , 1991, The Journal of biological chemistry.

[6]  C. Kahn,et al.  Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein , 1991, Nature.

[7]  J. Blenis,et al.  Coordinate regulation of pp90rsk and a distinct protein-serine/threonine kinase activity that phosphorylates recombinant pp90rsk in vitro , 1991, Molecular and cellular biology.

[8]  G. Lienhard,et al.  Insulin regulation of the two glucose transporters in 3T3-L1 adipocytes. , 1990, The Journal of biological chemistry.

[9]  A. Zorzano,et al.  Insulin-regulated glucose uptake in rat adipocytes is mediated by two transporter isoforms present in at least two vesicle populations. , 1989, The Journal of biological chemistry.

[10]  P. Taylor,et al.  An inositol tetrakisphosphate-containing phospholipid in activated neutrophils , 1988, Nature.

[11]  O. Rosen After insulin binds. , 1987, Science.

[12]  C. Kahn,et al.  Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells , 1985, Nature.