Labeling of cancer cells with magnetic nanoparticles for magnetic resonance imaging

The process of invasion and metastasis formation of tumor cells can be studied by following the migration of labeled cells over prolonged time periods. This report investigates the applicability of iron oxide nanoparticles as a magnetic resonance imaging (MRI) contrast agent for cell labeling.

[1]  Jinming Gao,et al.  Superparamagnetic Iron Oxide Nanoparticles: Amplifying ROS Stress to Improve Anticancer Drug Efficacy , 2013, Theranostics.

[2]  Ben Fabry,et al.  3D Traction Forces in Cancer Cell Invasion , 2012, PloS one.

[3]  Q. Vuong,et al.  Monte Carlo simulation and theory of proton NMR transverse relaxation induced by aggregation of magnetic particles used as MRI contrast agents. , 2011, Journal of magnetic resonance.

[4]  Ben Fabry,et al.  Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces , 2011, Journal of Cell Science.

[5]  Florence Gazeau,et al.  Degradability of superparamagnetic nanoparticles in a model of intracellular environment: follow-up of magnetic, structural and chemical properties , 2010, Nanotechnology.

[6]  Matthew R J Carroll,et al.  Experimental validation of proton transverse relaxivity models for superparamagnetic nanoparticle MRI contrast agents , 2010, Nanotechnology.

[7]  Peter M Jakob,et al.  Iron oxide labelling of human mesenchymal stem cells in collagen hydrogels for articular cartilage repair. , 2008, Biomaterials.

[8]  J. Snir,et al.  Cellular Magnetic Resonance Imaging : In Vivo Imaging of Melanoma Cells in Lymph Nodes of Mice 1 , 2008 .

[9]  C. Selomulya,et al.  Insight into microstructural and magnetic properties of flame-made γ-Fe2O3 nanoparticles , 2007 .

[10]  C. Selomulya,et al.  Flame-sprayed superparamagnetic bare and silica-coated maghemite nanoparticles : Synthesis, characterization, and protein adsorption-desorption , 2006 .

[11]  Bobbi K Lewis,et al.  A model of lysosomal metabolism of dextran coated superparamagnetic iron oxide (SPIO) nanoparticles: implications for cellular magnetic resonance imaging , 2005, NMR in biomedicine.

[12]  Nicolas Grenier,et al.  In vivo MR imaging of intravascularly injected magnetically labeled mesenchymal stem cells in rat kidney and liver. , 2004, Radiology.

[13]  Jeff W M Bulte,et al.  Feridex labeling of mesenchymal stem cells inhibits chondrogenesis but not adipogenesis or osteogenesis , 2004, NMR in biomedicine.

[14]  J. Riemer,et al.  Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells. , 2004, Analytical biochemistry.

[15]  A. Halayko,et al.  Mechanical strain inhibits airway smooth muscle gene transcription via protein kinase C signaling. , 2004, American journal of respiratory cell and molecular biology.

[16]  Heather Kalish,et al.  Characterization of biophysical and metabolic properties of cells labeled with superparamagnetic iron oxide nanoparticles and transfection agent for cellular MR imaging. , 2003, Radiology.

[17]  B. Rutt,et al.  Application of the static dephasing regime theory to superparamagnetic iron‐oxide loaded cells , 2002, Magnetic resonance in medicine.

[18]  J A Frank,et al.  Neurotransplantation of magnetically labeled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[19]  H. Ischiropoulos,et al.  Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. , 1992, Chemical research in toxicology.