Treatment of peri‐implant mucositis with a chitosan brush—A pilot randomized clinical trial

OBJECTIVE This aim of this study was to evaluate a chitosan brush for the treatment of peri-implant mucositis. MATERIALS AND METHODS A total of 11 patients with a combined total of 24 dental implants and who were diagnosed with peri-implant mucositis were included in this 6-month, split mouth, pilot clinical trial. Implants were randomly assigned to either treatment with a chitosan brush using an oscillating dental hand piece or treatment with titanium curettes. Supportive treatment was provided at 3 months. Two calibrated periodontists, blinded to treatment group, performed all examinations, including probing pocket depths (PPD) and bleeding on probing (mBoP). The changes in clinical parameters were compared between groups at 2 weeks, 4 weeks and 6 months. A Mann-Whitney U test with an alpha level of 0.05 was used for the statistical analyses. RESULTS Both groups demonstrated significant reductions in mBoP between baseline and 6 months. The test implants treated with the chitosan brush had a better improvement in mBoP at 2 weeks and 4 weeks compared to the implants treated with the titanium curettes. The reduction in PPD was significantly better in the test group at 4 weeks. All implants had stable bone levels, as seen on radiographs between baseline and 6 months. CONCLUSION Reduced signs of inflammation were seen in both groups 6 months after the baseline treatment and 3 months after maintenance. A chitosan brush seems to be a safe and efficient device for debridement of dental implants.

[1]  A. Wennerberg,et al.  Antimicrobial Effects of Three Different Treatment Modalities on Dental Implant Surfaces. , 2017, The Journal of oral implantology.

[2]  H. Jansson,et al.  A novel non-surgical method for mild peri-implantitis- a multicenter consecutive case series , 2017, International Journal of Implant Dentistry.

[3]  M. Korsch,et al.  Cement‐associated peri‐implant mucositis. A 1‐year follow‐up after excess cement removal on the peri‐implant tissue of dental implants , 2017, Clinical implant dentistry and related research.

[4]  D. Kohavi,et al.  Scaling of titanium implants entrains inflammation-induced osteolysis , 2017, Scientific Reports.

[5]  J. Díaz-Rodríguez,et al.  Role of supportive maintenance therapy on implant survival: a university-based 17 years retrospective analysis. , 2016, International journal of dental hygiene.

[6]  Hom-lay Wang,et al.  Non-Surgical Therapy for Peri-Implant Diseases: a Systematic Review , 2016, Journal of oral & maxillofacial research.

[7]  N. Lang,et al.  Dental floss as a possible risk for the development of peri-implant disease: an observational study of 10 cases. , 2016, Clinical oral implants research.

[8]  A. Catena,et al.  Impact of Maintenance Therapy for the Prevention of Peri-implant Diseases , 2016, Journal of dental research.

[9]  M. Monjo,et al.  Suture materials affect peri-implant bone healing and implant osseointegration. , 2015, Journal of oral science.

[10]  F. Schwarz,et al.  Efficacy of alternative or adjunctive measures to conventional treatment of peri-implant mucositis and peri-implantitis: a systematic review and meta-analysis , 2015, International Journal of Implant Dentistry.

[11]  O. Norderyd,et al.  Treatment of peri-implant mucositis using a glycine powder air-polishing or ultrasonic device: a randomized clinical trial. , 2015, Journal of clinical periodontology.

[12]  I. Chapple,et al.  Primary and secondary prevention of periodontal and peri-implant diseases: Introduction to, and objectives of the 11th European Workshop on Periodontology consensus conference. , 2015, Journal of clinical periodontology.

[13]  I. Polyzois,et al.  Risk indicators for peri-implant mucositis: a systematic literature review. , 2015, Journal of clinical periodontology.

[14]  R. Genco,et al.  Primary prevention of peri-implantitis: managing peri-implant mucositis. , 2015, Journal of clinical periodontology.

[15]  Ren Wang,et al.  Effect of glycine powder air-polishing as an adjunct in the treatment of peri-implant mucositis: a pilot clinical trial. , 2014, Clinical oral implants research.

[16]  J. Grytten,et al.  A comparison of teeth and implants during maintenance therapy in terms of the number of disease-free years and costs -- an in vivo internal control study. , 2013, Journal of clinical periodontology.

[17]  F. Tavaria,et al.  Evaluation and insights into chitosan antimicrobial activity against anaerobic oral pathogens. , 2012, Anaerobe.

[18]  F. Costa,et al.  Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. , 2012, Journal of clinical periodontology.

[19]  S. C. Lea,et al.  Effect of plastic-covered ultrasonic scalers on titanium implant surfaces. , 2012, Clinical oral implants research.

[20]  G. R. Persson,et al.  Treatment of peri-implantitis using an Er:YAG laser or an air-abrasive device: a randomized clinical trial. , 2011, Journal of clinical periodontology.

[21]  G. Serino,et al.  Peri-implantitis in partially edentulous patients: association with inadequate plaque control. , 2009, Clinical oral implants research.

[22]  S. Madihally,et al.  Antibacterial activity of chitosan-based matrices on oral pathogens , 2008, Journal of materials science. Materials in medicine.

[23]  A. Roos-Jansåker,et al.  Submerged healing following surgical treatment of peri-implantitis: a case series. , 2007, Journal of clinical periodontology.

[24]  K. Y. Kim,et al.  In vitro antimicrobial activity of a chitooligosaccharide mixture against Actinobacillus actinomycetemcomitans and Streptococcus mutans. , 2001, International journal of antimicrobial agents.

[25]  S. Jepsen,et al.  Progressive peri-implantitis. Incidence and prediction of peri-implant attachment loss. , 1996, Clinical oral implants research.

[26]  N. Lang,et al.  Histologic probe penetration in healthy and inflamed peri-implant tissues. , 1994, Clinical oral implants research.