Radiosynthesis of [11C]SNAP-7941—the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1)

[1]  W. Gattrell,et al.  An example of designed multiple ligands spanning protein classes: dual MCH-1R antagonists/DPPIV inhibitors. , 2012, Bioorganic & medicinal chemistry letters.

[2]  C. Pothoulakis,et al.  Melanin-concentrating hormone as a mediator of intestinal inflammation , 2008, Proceedings of the National Academy of Sciences.

[3]  D. Luthin.  Anti-obesity effects of small molecule melanin-concentrating hormone receptor1 (MCHR1) antagonists , 2007 .

[4]  J. Schönberger.  Studien zur Entwicklung neuer Leitstrukturen für die medikamentöse Adipositastherapie , 2006 .

[5]  H. Iwaasa,et al.  Characterization of MCH-mediated obesity in mice. , 2003, American journal of physiology. Endocrinology and metabolism.

[6]  C. Elias,et al.  Distribution of melanin-concentrating hormone neurons projecting to the medial mammillary nucleus , 2002, Neuroscience.

[7]  B. Cheatham,et al.  Melanin-concentrating hormone activates signaling pathways in 3T3-L1 adipocytes. , 2002, American journal of physiology. Endocrinology and metabolism.

[8]  Beth Borowsky,et al.  Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist , 2002, Nature Medicine.

[9]  Yue Feng,et al.  Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[10]  B. Hawes,et al.  Identification and Pharmacological Characterization of a Novel Human Melanin-concentrating Hormone Receptor, MCH-R2* , 2001, The Journal of Biological Chemistry.

[11]  W Li,et al.  Identification and characterization of a melanin-concentrating hormone receptor , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[12]  Christopher P. Austin,et al.  Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[13]  J. Chambers,et al.  Molecular Cloning and Functional Characterization of MCH2, a Novel Human MCH Receptor* , 2001, The Journal of Biological Chemistry.

[14]  G. Hervieu,et al.  Expression of melanin-concentrating hormone receptors in insulin-producing cells: MCH stimulates insulin release in RINm5F and CRI-G1 cell-lines. , 2000, Biochemical and biophysical research communications.

[15]  B. Cheatham,et al.  Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes. , 2000, Diabetes.

[16]  E. Grazzini,et al.  The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor , 1999, Nature Cell Biology.

[17]  O. Nishimura,et al.  Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor. , 1999, Biochemical and biophysical research communications.

[18]  J. Chambers,et al.  Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1 , 1999, Nature.

[19]  Yumiko Saito,et al.  Molecular characterization of the melanin-concentrating-hormone receptor , 1999, Nature.

[20]  J. Vaughan,et al.  The melanin‐concentrating hormone system of the rat brain: An immuno‐ and hybridization histochemical characterization , 1992, The Journal of comparative neurology.

[21]  H. Kawauchi,et al.  Characterization of melanin-concentrating hormone in chum salmon pituitaries , 1983, Nature.