Imatinib mesylate minimally affects bcr‐abl+ and normal monocyte‐derived dendritic cells but strongly inhibits T cell expansion despite reciprocal dendritic cell‐T cell activation
暂无分享,去创建一个
J. Soulier | J. Cayuela | H. Dombret | A. Toubert | P. Rousselot | N. Boissel | D. Charron | E. Raffoux | N. Mooney | D. Réa
[1] E. Wagner,et al. BCR/ABL promotes dendritic cell-mediated natural killer cell activation. , 2005, Cancer research.
[2] Jin Xie,et al. Critical roles of Raf/MEK/ERK and PI3K/AKT signaling and inactivation of p38 MAP kinase in the differentiation and survival of monocyte-derived immature dendritic cells. , 2005, Experimental hematology.
[3] D. Douek,et al. Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. , 2005, Blood.
[4] O. Schoor,et al. Effects of Imatinib on Monocyte-Derived Dendritic Cells Are Mediated by Inhibition of Nuclear Factor-κB and Akt Signaling Pathways , 2005, Clinical Cancer Research.
[5] C. Sawyers,et al. Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment. , 2005, Blood.
[6] J. Taylor‐Papadimitriou,et al. Apoptosis of monocytes and the influence on yield of monocyte-derived dendritic cells. , 2004, Journal of immunological methods.
[7] J. Cayuela,et al. Defective blood dendritic cells in chronic myeloid leukemia correlate with high plasmatic VEGF and are not normalized by imatinib mesylate , 2004, Leukemia.
[8] H. Ploegh,et al. Upregulation of the CLIP self peptide on mature dendritic cells antagonizes T helper type 1 polarization , 2004, Nature Immunology.
[9] J. Berkhof,et al. Class II-Associated Invariant Chain Peptide Expression on Myeloid Leukemic Blasts Predicts Poor Clinical Outcome , 2004, Cancer Research.
[10] Lina Souan,et al. Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo. , 2004, Blood.
[11] J. Melo,et al. Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro , 2004, Leukemia.
[12] P. Zipfel,et al. Requirement for Abl Kinases in T Cell Receptor Signaling , 2004, Current Biology.
[13] B. Druker,et al. Divergent clinical outcome in two CML patients who discontinued imatinib therapy after achieving a molecular remission. , 2004, Leukemia research.
[14] C. Figdor,et al. Dendritic cell immunotherapy: mapping the way , 2004, Nature Medicine.
[15] R. Foà,et al. IFN-alpha promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment. , 2004, Blood.
[16] T. Brümmendorf,et al. Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells. , 2004, Blood.
[17] H. Cavé,et al. Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program , 2003, Leukemia.
[18] D. Douek,et al. Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation. , 2003, Blood.
[19] Susan Branford,et al. Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia. , 2003, The New England journal of medicine.
[20] H. Hirai,et al. Dendritic cell vaccination for patients with chronic myelogenous leukemia. , 2003, Leukemia research.
[21] A. B. Lyons,et al. Imatinib inhibits the in vitro development of the monocyte/macrophage lineage from normal human bone marrow progenitors , 2003, Leukemia.
[22] G. Ossenkoppele,et al. Vaccination of chronic myeloid leukemia patients with autologous in vitro cultured leukemic dendritic cells , 2003, Leukemia.
[23] Guoping Feng,et al. Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction , 2003, Nature Neuroscience.
[24] Francisco Cervantes,et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. , 2003, The New England journal of medicine.
[25] Martin C. Müller,et al. Interferon-α, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia , 2003 .
[26] C. Sawyers,et al. Interferon-α induces dendritic cell differentiation of CML mononuclear cells in vitro and in vivo , 2002, Leukemia.
[27] Antonio Lanzavecchia,et al. Regulation of T Cell Immunity by Dendritic Cells , 2001, Cell.
[28] P. Allen,et al. Kissing cousins: immunological and neurological synapses , 2001, Nature Immunology.
[29] M. Soloski,et al. Physiological Regulation of the Immunological Synapse by Agrin , 2001, Science.
[30] C. Sawyers,et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. , 2001, The New England journal of medicine.
[31] F. Sallusto,et al. Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells , 2000, Nature Immunology.
[32] Mark M. Davis,et al. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia , 2000, Nature Medicine.
[33] J. Goldman,et al. Selective elimination of leukemic CD34(+) progenitor cells by cytotoxic T lymphocytes specific for WT1. , 2000, Blood.
[34] O. Majdic,et al. Neutrophil Granulocyte–committed Cells Can Be Driven to Acquire Dendritic Cell Characteristics , 1998, The Journal of experimental medicine.
[35] C Danieli,et al. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products , 1995, The Journal of experimental medicine.
[36] F. Sallusto,et al. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha , 1994, The Journal of experimental medicine.
[37] D. H. Mellor,et al. Real time , 1981 .