论文信息 - Quality Assessment of Different Variants of Yogaraj Guggulu

Quality Assessment of Different Variants of Yogaraj Guggulu

Yogaraj-guggulu is a widely used Ayurvedic formulation.Standardisation of the Ayurvedic medicine, Yogaraja guggulu has been achieved by following modern scientific quality control procedures. It has been shown to have significant anti-inflammatory activity in formaldehyde-induced arthritis and in croton oil granuloma. For the standardization of this drug physico-chemical parameters were carried out such as moisture content, ash values, extractability in water and alcohol were carried out. Thin Layer Chromatography studies were also carried out to ascertain the quality of this drug.

[1] R. Dhir,et al. Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak , 2005, Molecular Cancer Therapeutics.

[2] Betsy B. Singh,et al. The effectiveness of Commiphora mukul for osteoarthritis of the knee: an outcomes study. , 2003, Alternative therapies in health and medicine.

[3] S. Dev,et al. CHEMISTRY OF AYURVEDIC CRUDE DRUGS PART 3, GUGGULU (RESIN FROM COMMIPHORA MUKUL) PART 3, LONG-CHAIN ALIPHATIC TETROLS, A NEW CLASS OF NATURALLY OCCURRING LIPIDS , 1973 .

[4] S. Dev,et al. Chemistry of Ayurvedic crude drugs—I : Guggulu (resin from Commiphora mukul)—1: Steroidal constituents , 1972 .

[5] O. P. Agarwal,et al. A biochemical approach to anti-atherosclerotic action of Commiphora-mukul: an Indian indigenous drug in Indian domestic pigs (Sus scrofa). , 1969, The Indian journal of medical research.