Approaching health disparities from a population perspective: the National Institutes of Health Centers for Population Health and Health Disparities.

Addressing health disparities has been a national challenge for decades. The National Institutes of Health-sponsored Centers for Population Health and Health Disparities are the first federal initiative to support transdisciplinary multilevel research on the determinants of health disparities. Their novel research approach combines population, clinical, and basic science to elucidate the complex determinants of health disparities. The centers are partnering with community-based, public, and quasi-public organizations to disseminate scientific findings and guide clinical practice in communities. In turn, communities and public health agents are shaping the research. The relationships forged through these complex collaborations increase the likelihood that the centers' scientific findings will be relevant to communities and contribute to reductions in health disparities.

[1]  M. Stoto,et al.  Linking Research and Public Health Practice: A Review of CDC's Program of Centers for Research and Demonstration of Health Promotion and Disease Prevention , 1997 .

[2]  L. Hawkley,et al.  Loneliness and Health: Potential Mechanisms , 2002, Psychosomatic medicine.

[3]  Craig Duncan,et al.  Multilevel methods for public health research , 2000 .

[4]  M. McClintock,et al.  Mammary Cancer and Social Interactions: Identifying Multiple Environments That Regulate Gene Expression Throughout the Life Span. , 2005, The journals of gerontology. Series B, Psychological sciences and social sciences.

[5]  M. Marmot The Status Syndrome: How Social Standing Affects Our Health and Longevity , 2004 .

[6]  A. Crouter,et al.  How do Communities Undergird or Undermine Human Development? Relevant Contexts and Social Mechanisms , 2001 .

[7]  Burton H. Singer,et al.  New Horizons in Health: An Integrative Approach , 2001 .

[8]  Wei Wu,et al.  Microarray Analysis Reveals Glucocorticoid-Regulated Survival Genes That Are Associated With Inhibition of Apoptosis in Breast Epithelial Cells , 2004, Cancer Research.

[9]  Bruce G. Link,et al.  Social Conditions as Fundamental Causes of Disease , 1995 .

[10]  A. Montag,et al.  CALL FOR PAPERS Sex and Gender Differences in Pain and Inflammation Social isolation and the inflammatory response: sex differences in the enduring effects of a prior stressor , 2005 .

[11]  M. Lagory,et al.  Unhealthy Places: The Ecology of Risk in the Urban Landscape , 2000 .

[12]  H. Joshi,et al.  Higher mortality in deprived areas: community or personal disadvantage? , 1994, BMJ.

[13]  C. R. Snyder,et al.  Handbook of positive psychology , 2002 .

[14]  J. Goodwin,et al.  Mortality of foreign-born and US-born Hispanic adults at younger ages: a reexamination of recent patterns. , 2007, American journal of public health.

[15]  B. Soldo,et al.  Racial and Ethnic Differences in the Health of Older Americans , 1997 .

[16]  Terrence D. Hill,et al.  Neighborhood Disorder, Psychophysiological Distress, and Health∗ , 2005, Journal of health and social behavior.

[17]  Shelley E. Taylor,et al.  Health psychology: what is an unhealthy environment and how does it get under the skin? , 1997, Annual review of psychology.

[18]  Judith A. Long,et al.  Eliminating health disparities through transdisciplinary research, cross-agency collaboration, and public participation. , 2009, American journal of public health.

[19]  K. Tucker,et al.  Prevalence and correlates of depressive symptoms among Hispanic elders in Massachusetts. , 2000, The journals of gerontology. Series B, Psychological sciences and social sciences.

[20]  D. Shaw,et al.  Social determinants of health, 2nd edn , 2008 .

[21]  R. Barrett,et al.  Neighborhood change and distant metastasis at diagnosis of breast cancer. , 2008, Annals of epidemiology.

[22]  J. House,et al.  Social relationships and health. , 1988, Science.

[23]  A. Baum,et al.  Socioeconomic Status and Chronic Stress: Does Stress Account for SES Effects on Health? , 1999, Annals of the New York Academy of Sciences.

[24]  L. Kantor,et al.  NIH Roadmap for Medical Research , 2008, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

[25]  T. Seeman,et al.  Protective and Damaging Effects of Mediators of Stress: Elaborating and Testing the Concepts of Allostasis and Allostatic Load , 1999, Annals of the New York Academy of Sciences.

[26]  K. Glanz,et al.  Health behavior and health education : theory, research, and practice , 1991 .

[27]  K. Tucker,et al.  Self-reported prevalence and health correlates of functional limitation among Massachusetts elderly Puerto Ricans, Dominicans, and non-Hispanic white neighborhood comparison group. , 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.

[28]  J. Goodwin,et al.  Ascertainment of Hispanic ethnicity on California death certificates: implications for the explanation of the Hispanic mortality advantage. , 2006, American journal of public health.

[29]  K. Tucker,et al.  Type 2 diabetes is prevalent and poorly controlled among Hispanic elders of Caribbean origin. , 2000, American journal of public health.

[30]  C. Ross,et al.  Neighborhood disadvantage, disorder, and health. , 2001, Journal of health and social behavior.

[31]  Laurence E. Lynn,et al.  Inner-city poverty in the United States , 1990 .

[32]  B. Singer,et al.  From social structure to biology: Integrative science in pursuit of human health and well-being. , 2002 .

[33]  Ichiro Kawachi,et al.  Neighborhood differences in social capital: a compositional artifact or a contextual construct? , 2003, Health & place.

[34]  L. Berkman,et al.  From social integration to health: Durkheim in the new millennium. , 2000, Social science & medicine.

[35]  M. Elliott,et al.  The stress process in neighborhood context. , 2000, Health & place.

[36]  David J. Rapport,et al.  Rebuilding the Unity of Health and the Environment: A New Vision of Environmental Health for the 21st Century. , 2001 .

[37]  Robert J. Sampson,et al.  Neighborhood-Level Context and Health: Lessons from Sociology , 2003 .

[38]  Kelvyn Jones,et al.  Individuals and their ecologies: analysing the geography of chronic illness within a multilevel modelling framework , 1995 .

[39]  T. Rebbeck,et al.  CYP3A4, CYP3A5, and CYP3A43 Genotypes and Haplotypes in the Etiology and Severity of Prostate Cancer , 2004, Cancer Research.

[40]  B. Smedley,et al.  The unequal burden of cancer : an assessment of NIH research and programs for ethnic minorities and the medically underserved , 1999 .

[41]  T. Seeman Social ties and health: the benefits of social integration. , 1996, Annals of epidemiology.

[42]  Richard G. Rogers,et al.  Race Differentials in Obesity: The Impact of Place∗ , 2005, Journal of health and social behavior.

[43]  Malcolm P Cutchin,et al.  Concern About Petrochemical Health Risk Before and After a Refinery Explosion , 2008, Risk analysis : an official publication of the Society for Risk Analysis.

[44]  G W Comstock,et al.  Neighborhood environments and coronary heart disease: a multilevel analysis. , 1997, American journal of epidemiology.

[45]  Stephen W. Raudenbush,et al.  1. Ecometrics: Toward a Science of Assessing Ecological Settings, with Application to the Systematic Social Observation of Neighborhoods , 1999 .

[46]  B. Israel,et al.  Social networks and social support. , 2008 .

[47]  I. Kawachi,et al.  Social capital and neighborhood mortality rates in Chicago. , 2003, Social science & medicine.

[48]  T. Glass,et al.  Behavioral science at the crossroads in public health: extending horizons, envisioning the future. , 2006, Social science & medicine.

[49]  N. Anderson Levels of Analysis in Health Science: A Framework for Integrating Sociobehavioral and Biomedical Research , 1998, Annals of the New York Academy of Sciences.

[50]  P. Thoits,et al.  Stress, coping, and social support processes: where are we? What next? , 1995, Journal of health and social behavior.

[51]  J. Goodwin,et al.  Perceived health change in the aftermath of a petrochemical accident: an examination of pre-accident, within-accident, and post-accident variables , 2008, Journal of Epidemiology & Community Health.

[52]  K. Matthews,et al.  Do Negative Emotions Mediate the Association between Socioeconomic Status and Health? , 1999, Annals of the New York Academy of Sciences.

[53]  John Lynch,et al.  Methods for Measuring Cancer Disparities: Using Data Relevant to Healthy People 2010 Cancer-Related Objectives , 2005 .

[54]  G Rose,et al.  Sick individuals and sick populations. , 1985, International journal of epidemiology.

[55]  S. Syme,et al.  Promoting Health: Intervention Strategies from Social and Behavioral Research , 2001 .

[56]  A. Crouter,et al.  Does It Take a Village? Community Effects on Children, Adolescents, and Families. , 2001 .

[57]  M. Woolcock,et al.  Health and Wealth: Health by Association? Social Capital, Social Theory, and the Political Economy of Public Health , 2005 .

[58]  I. Kawachi Social cohesion, social capital and health , 2000 .

[59]  D. Kindig,et al.  Understanding Population Health Terminology , 2007, The Milbank quarterly.

[60]  K. Smith,et al.  Phantom of the area: poverty-area residence and mortality in the United States. , 1998, American journal of public health.