Is advanced life support better than basic life support in prehospital care? A systematic review

Background -Prehospital care is classified into ALS- (advanced life support) and BLS- (basic life support) levels according to the methods used. ALS-level prehospital care uses invasive methods, such as intravenous fluids, medications and intubation. However, the effectiveness of ALS care compared to BLS has been questionable.Aim -The aim of this systematic review is to compare the effectiveness of ALS- and BLS-level prehospital care.Material and methods -In a systematic review, articles where ALS-level prehospital care was compared to BLS-level or any other treatment were included. The outcome variables were mortality or patient's health-related quality of life or patient's capacity to perform daily activities.Results -We identified 46 articles, mostly retrospective observational studies. The results on the effectiveness of ALS in unselected patient cohorts are contradictory. In cardiac arrest, early cardiopulmonary resuscitation and defibrillation are essential for survival, but prehospital ALS interventions have not improved survival. Prehospital thrombolytic treatment reduces mortality in patients having a myocardial infarction. The majority of research into trauma favours BLS in the case of penetrating trauma and also in cases of short distance to a hospital. In patients with severe head injuries, ALS provided by paramedics and intubation without anaesthesia can even be harmful. If the prehospital care is provided by an experienced physician and by a HEMS organisation (Helicopter Emergency Medical Service), ALS interventions may be beneficial for patients with multiple injuries and severe brain injuries. However, the results are contradictory.Conclusions -ALS seems to improve survival in patients with myocardial infarction and BLS seems to be the proper level of care for patients with penetrating injuries. Some studies indicate a beneficial effect of ALS among patients with blunt head injuries or multiple injuries. There is also some evidence in favour of ALS among patients with epileptic seizures as well as those with a respiratory distress.

[1]  C. Gold,et al.  Prehospital advanced life support vs "scoop and run" in trauma management. , 1987, Annals of emergency medicine.

[2]  D. Ferriero,et al.  Effect of prehospital treatment on the outcome of status epilepticus in children. , 1995, Pediatric neurology.

[3]  J. Nicholl,et al.  Effects of London helicopter emergency medical service on survival after trauma , 1995, BMJ.

[4]  J. Boissel The European Myocardial Infarction Project: an assessment of pre-hospital thrombolysis. , 1995, International journal of cardiology.

[5]  M. Shuster,et al.  Effects of prehospital care on outcome in patients with cardiac illness. , 1995, Annals of emergency medicine.

[6]  R. Wolford,et al.  Does the Level of Prehospital Care Influence the Outcome of Patients with Altered Levels of Consciousness? , 1996, Prehospital and Disaster Medicine.

[7]  J. Nicholl,et al.  The costs and benefits of helicopter emergency ambulance services in England and Wales. , 1996, Journal of public health medicine.

[8]  T. Silfvast,et al.  The effect of experience of on-site physicians on survival from prehospital cardiac arrest. , 1996, Resuscitation.

[9]  H. Belzberg,et al.  Paramedic vs private transportation of trauma patients. Effect on outcome. , 1996, Archives of surgery.

[10]  T. Rainer,et al.  Paramedics, technicians, and survival from out of hospital cardiac arrest. , 1997, Journal of accident & emergency medicine.

[11]  T. Rainer,et al.  An evaluation of paramedic activities in prehospital trauma care. , 1997, Injury.

[12]  J. Nguyen-Van-Tam,et al.  Effectiveness of ambulance paramedics versus ambulance technicians in managing out of hospital cardiac arrest. , 1997, Journal of accident & emergency medicine.

[13]  K. Olkkola,et al.  Prehospital care and survival of pediatric patients with blunt trauma. , 1998, Journal of pediatric surgery.

[14]  P. Rosen,et al.  Aggressive out-of-hospital treatment regimen for severe closed head injury in patients undergoing air medical transport. , 1998, Air medical journal.

[15]  I. Dubinsky,et al.  Advanced life support vs basic life support field care: an outcome study. , 1998, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[16]  J. Owen,et al.  One year's trauma mortality experience at Brooke Army Medical Center: is aeromedical transportation of trauma patients necessary? , 1999, Military medicine.

[17]  T. Rainer,et al.  Paramedic activities, drug administration and survival from out of hospital cardiac arrest. , 2000, Resuscitation.

[18]  M. Eckstein,et al.  Effect of prehospital advanced life support on outcomes of major trauma patients. , 2000, The Journal of trauma.

[19]  J. Sampalis,et al.  Advanced or basic life support for trauma: meta-analysis and critical review of the literature. , 2000, The Journal of trauma.

[20]  F Bunn,et al.  Advanced trauma life support training for ambulance crews. , 2001, The Cochrane database of systematic reviews.

[21]  G. Nardi,et al.  Effects of 2 patterns of prehospital care on the outcome of patients with severe head injury. , 2001, Archives of surgery.

[22]  R. Pitetti,et al.  P REHOSPITAL C ARE AND O UTCOME OF P EDIATRIC O UT - OF - HOSPITAL C ARDIAC A RREST , 2002, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

[23]  E. Ruokonen,et al.  Paramedic helicopter emergency service in rural Finland – do benefits justify the cost? , 2002, Acta anaesthesiologica Scandinavica.

[24]  S. Wedel,et al.  Helicopter transport and blunt trauma mortality: a multicenter trial. , 2002, The Journal of trauma.

[25]  P. Steen,et al.  Prehospital advanced life support provided by specially trained physicians: is there a benefit in terms of life years gained? , 2002, Acta anaesthesiologica Scandinavica.

[26]  [Prehospital treatment of patients with acute exacerbation of chronic pulmonary disease. Before and after introduction of a mobile emergency unit]. , 2002, Ugeskrift for laeger.

[27]  S. Wedel,et al.  T RAUMA H ELICOPTER E MERGENCY M EDICAL S ERVICES T RANSPORT : A NNOTATED R EVIEW OF S ELECTED O UTCOMES-RELATED L ITERATURE , 2002, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

[28]  A. Garner,et al.  Level of prehospital care and risk of mortality in patients with and without severe blunt head injury. , 2003, Injury.

[29]  Wales. A REVIEW OF THE COSTS AND BENEFITS OF HELICOPTER EMERGENCY AMBULANCE SERVICES , 2003 .

[30]  J. Sampalis,et al.  Multicenter Canadian Study of Prehospital Trauma Care , 2003, Annals of surgery.

[31]  J. Søgaard,et al.  Anesthesiologists in prehospital care make a difference to certain groups of patients , 2003, Acta anaesthesiologica Scandinavica.

[32]  J. Osterwalder Mortality of blunt polytrauma: a comparison between emergency physicians and emergency medical technicians--prospective cohort study at a level I hospital in eastern Switzerland. , 2003, The Journal of trauma.

[33]  Thomas M Scalea,et al.  Endotracheal intubation in the field does not improve outcome in trauma patients who present without an acutely lethal traumatic brain injury. , 2003, The Journal of trauma.

[34]  H. Zwipp,et al.  Impact of helicopter transport and hospital level on mortality of polytrauma patients. , 2004, The Journal of trauma.

[35]  A. V. van Vugt,et al.  Beneficial effect of helicopter emergency medical services on survival of severely injured patients , 2004, The British journal of surgery.

[36]  D. Cone Multicenter Canadian study of prehospital trauma care , 2004 .

[37]  J. Henry,et al.  Prehospital trauma management: a national study of paramedic activities , 2004, Emergency Medicine Journal.

[38]  S. Thomas HELICOPTER EMERGENCY MEDICAL SERVICES TRANSPORT OUTCOMES LITERATURE: ANNOTATED REVIEW OF ARTICLES PUBLISHED 2000–2003 , 2004, Prehospital Emergency Care.

[39]  P. Steg,et al.  Impact of Prehospital Thrombolysis for Acute Myocardial Infarction on 1-Year Outcome: Results From the French Nationwide USIC 2000 Registry , 2004, Circulation.

[40]  Henry E. Wang,et al.  Out-of-hospital endotracheal intubation and outcome after traumatic brain injury. , 2004, Annals of emergency medicine.

[41]  A. Garner The role of physician staffing of helicopter emergency medical services in prehospital trauma response. , 2004, Emergency medicine Australasia : EMA.

[42]  George A. Wells,et al.  Advanced Cardiac Life Support in Out-of-Hospital Cardiac Arrest , 2004 .

[43]  Stephen Cameron,et al.  Helicopter primary retrieval: Tasking who should do it? , 2005, Emergency medicine Australasia : EMA.

[44]  D. Isenberg,et al.  Does Advanced Life Support Provide Benefits to Patients?: A Literature Review , 2005, Prehospital and Disaster Medicine.

[45]  G. Nardi,et al.  HEMS VS. GROUND-BLS CARE IN TRAUMATIC CARDIAC ARREST , 2005, Prehospital Emergency Care.

[46]  Fernando Rosell Ortiz,et al.  [Out-of-hospital treatment of acute myocardial infarction in Andalusia, Spain]. , 2005 .

[47]  F. Rosell Ortiz,et al.  [Out-of-hospital treatment of acute myocardial infarction in Andalusia, Spain]. , 2005, Revista espanola de cardiologia.

[48]  F. Ortiz,et al.  Tratamiento extrahospitalario del infarto agudo de miocardio en Andalucía , 2005 .

[49]  Colleen Buono,et al.  The impact of aeromedical response to patients with moderate to severe traumatic brain injury. , 2005, Annals of emergency medicine.

[50]  P. Klemen,et al.  Effect of pre‐hospital advanced life support with rapid sequence intubation on outcome of severe traumatic brain injury , 2006, Acta anaesthesiologica Scandinavica.

[51]  T. Vahlberg,et al.  Effect of physician-staffed helicopter emergency medical service on blunt trauma patient survival and prehospital care , 2006, European journal of emergency medicine : official journal of the European Society for Emergency Medicine.

[52]  L. Wallentin,et al.  Pre-hospital thrombolysis delivered by paramedics is associated with reduced time delay and mortality in ambulance-transported real-life patients with ST-elevation myocardial infarction. , 2006, European heart journal.

[53]  M. Liberman,et al.  Prehospital trauma care: what do we really know? , 2007, Current opinion in critical care.

[54]  Marion Lyver,et al.  Advanced life support for out-of-hospital respiratory distress. , 2007, The New England journal of medicine.

[55]  Jon Nicholl,et al.  The relationship between distance to hospital and patient mortality in emergencies: an observational study , 2007, Emergency Medicine Journal.

[56]  Chien-Hwa Hwang,et al.  Outcomes from out-of-hospital cardiac arrest in Metropolitan Taipei: does an advanced life support service make a difference? , 2007, Resuscitation.

[57]  M. Seamon,et al.  Prehospital procedures before emergency department thoracotomy: "scoop and run" saves lives. , 2007, The Journal of trauma.

[58]  S. Thomas Helicopter EMS transport outcomes literature: annotated review of articles published 2004-2006. , 2014, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

[59]  V. Tippett,et al.  Impact of advanced cardiac life support-skilled paramedics on survival from out-of-hospital cardiac arrest in a statewide emergency medical service , 2007, Emergency Medicine Journal.

[60]  A. Exadaktylos,et al.  Isolated vertebral fractures give elevated serum protein S-100B levels , 2008, Scandinavian journal of trauma, resuscitation and emergency medicine.

[61]  I. Stiell,et al.  The OPALS Major Trauma Study: impact of advanced life-support on survival and morbidity , 2008, Canadian Medical Association Journal.