Lateral hypothalamic leptin receptor neurons drive hunger-gated food-seeking and consummatory behaviours in male mice

[1]  B. Lim,et al.  Early adversity promotes binge-like eating habits by remodeling a leptin-responsive lateral hypothalamus–brainstem pathway , 2022, Nature Neuroscience.

[2]  Bin Yang,et al.  Transformations of neural representations in a social behaviour network , 2022, Nature.

[3]  M. Krashes,et al.  Acts of appetite: neural circuits governing the appetitive, consummatory, and terminating phases of feeding , 2022, Nature Metabolism.

[4]  Andrew L. Lemire,et al.  EASI-FISH for thick tissue defines lateral hypothalamus spatio-molecular organization , 2021, Cell.

[5]  Sung-Yon Kim,et al.  A forebrain neural substrate for behavioral thermoregulation , 2021, Neuron.

[6]  W. Langhans,et al.  The Physiological Control of Eating: Signals, Neurons, and Networks. , 2021, Physiological reviews.

[7]  M. Andermann,et al.  Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling , 2021, Nature.

[8]  Sarah Sarsfield,et al.  Lateral hypothalamic LEPR neurons drive appetitive but not consummatory behaviors , 2021, Cell reports.

[9]  Miao He,et al.  The tectonigral pathway regulates appetitive locomotion in predatory hunting in mice , 2021, Nature Communications.

[10]  S. Kim,et al.  Minhee Analysis Package: an integrated software package for detection and management of spontaneous synaptic events , 2021, bioRxiv.

[11]  S. Liberles,et al.  Hunger enhances food odor attraction through a Neuropeptide Y spotlight , 2021, Nature.

[12]  R. Adan,et al.  Identification of Novel Neurocircuitry Through Which Leptin Targets Multiple Inputs to the Dopamine System to Reduce Food Reward Seeking , 2021, Biological Psychiatry.

[13]  R. Wise,et al.  Control of food approach and eating by a GABAergic projection from lateral hypothalamus to dorsal pons , 2020, Proceedings of the National Academy of Sciences.

[14]  S. E. Fleur,et al.  Neuropeptide Y Signaling in the Lateral Hypothalamus Modulates Diet Component Selection and is Dysregulated in a Model of Diet-Induced Obesity , 2019, Neuroscience.

[15]  Y. Yoshimura,et al.  Hypothalamic neuronal circuits regulating hunger-induced taste modification , 2019, Nature Communications.

[16]  S. Duan,et al.  The Lateral Hypothalamic and BNST GABAergic Projections to the Anterior Ventrolateral Periaqueductal Gray Regulate Feeding. , 2019, Cell reports.

[17]  B. Laing,et al.  Activation of a lateral hypothalamic-ventral tegmental circuit gates motivation , 2019, PloS one.

[18]  S. Borgland,et al.  Diversity in the lateral hypothalamic input to the ventral tegmental area , 2019, Neuropharmacology.

[19]  R. Adan,et al.  Effects of GABA and Leptin Receptor‐Expressing Neurons in the Lateral Hypothalamus on Feeding, Locomotion, and Thermogenesis , 2019, Obesity.

[20]  Yiming Chen,et al.  Sustained NPY signaling enables AgRP neurons to drive feeding , 2019, eLife.

[21]  You Bin Kim,et al.  Food Craving, Seeking, and Consumption Behaviors: Conceptual Phases and Assessment Methods Used in Animal and Human Studies , 2019, Journal of obesity & metabolic syndrome.

[22]  Mohan Bolisetty,et al.  Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons , 2019, Nature Neuroscience.

[23]  Andrew J. Hill,et al.  The single cell transcriptional landscape of mammalian organogenesis , 2019, Nature.

[24]  Cole Trapnell,et al.  Connect-seq to superimpose molecular on anatomical neural circuit maps , 2018, Proceedings of the National Academy of Sciences.

[25]  Kevin M. Cury,et al.  DeepLabCut: markerless pose estimation of user-defined body parts with deep learning , 2018, Nature Neuroscience.

[26]  R. Malenka,et al.  PARALLEL CIRCUITS FROM THE BED NUCLEI OF STRIA TERMINALIS TO THE LATERAL HYPOTHALAMUS DRIVE OPPOSING EMOTIONAL STATES , 2018, Nature Neuroscience.

[27]  Z. Andrews,et al.  The role of corticostriatal–hypothalamic neural circuits in feeding behaviour: implications for obesity , 2018, Journal of neurochemistry.

[28]  H. Berthoud,et al.  Galanin-Expressing GABA Neurons in the Lateral Hypothalamus Modulate Food Reward and Noncompulsive Locomotion , 2017, The Journal of Neuroscience.

[29]  R. Naik Ramesh,et al.  Homeostatic circuits selectively gate food cue responses in insular cortex , 2017, Nature.

[30]  D. Burdakov,et al.  Orexin-driven GAD65 network of the lateral hypothalamus sets physical activity in mice , 2017, Proceedings of the National Academy of Sciences.

[31]  S. Sternson,et al.  Three Pillars for the Neural Control of Appetite. , 2017, Annual review of physiology.

[32]  C. Saper,et al.  A Novel Population of Wake-Promoting GABAergic Neurons in the Ventral Lateral Hypothalamus , 2016, Current Biology.

[33]  Edward H. Nieh,et al.  Inhibitory Input from the Lateral Hypothalamus to the Ventral Tegmental Area Disinhibits Dopamine Neurons and Promotes Behavioral Activation , 2016, Neuron.

[34]  Christopher M. Mazzone,et al.  Lateral Hypothalamus GABAergic Neurons Modulate Consummatory Behaviors Regardless of the Caloric Content or Biological Relevance of the Consumed Stimuli , 2016, Neuropsychopharmacology.

[35]  R. Wise,et al.  Lateral hypothalamic circuits for feeding and reward , 2016, Nature Neuroscience.

[36]  T. Knöpfel,et al.  Optogenetics enlightens neuroscience drug discovery , 2015, Nature Reviews Drug Discovery.

[37]  Talia N. Lerner,et al.  Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits , 2015, Cell.

[38]  J. Betley,et al.  Neurons for hunger and thirst transmit a negative-valence teaching signal , 2015, Nature.

[39]  Karl Deisseroth,et al.  Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors , 2015, Cell.

[40]  Stephen A. Allsop,et al.  Decoding Neural Circuits that Control Compulsive Sucrose Seeking , 2015, Cell.

[41]  S. Luquet,et al.  Arcuate AgRP neurons and the regulation of energy balance , 2012, Front. Endocrin..

[42]  D. R. Euston,et al.  The Role of Medial Prefrontal Cortex in Memory and Decision Making , 2012, Neuron.

[43]  Joseph E LeDoux.  Rethinking the Emotional Brain , 2012, Neuron.

[44]  Lei Zhang,et al.  NPY receptors as potential targets for anti‐obesity drug development , 2011, British journal of pharmacology.

[45]  S. Sternson,et al.  AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training , 2010, Nature Neuroscience.

[46]  H. Münzberg,et al.  Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. , 2009, Cell metabolism.

[47]  A. Kalsbeek,et al.  Differential Effects of Recombinant Adeno-Associated Virus-Mediated Neuropeptide Y Overexpression in the Hypothalamic Paraventricular Nucleus and Lateral Hypothalamus on Feeding Behavior , 2007, The Journal of Neuroscience.

[48]  B. Henry.  Hypothalamic Control of Food Intake and Body Weight , 2007 .

[49]  T. Hökfelt,et al.  Distribution of NPY receptors in the hypothalamus , 2004, Neuropeptides.

[50]  K. Berridge.  Motivation concepts in behavioral neuroscience , 2004, Physiology & Behavior.

[51]  T. Hexum,et al.  Neuropeptide Y Receptor-Mediated Sensitization of ATP-Stimulated Inositol Phosphate Formation , 2003, Journal of Pharmacology and Experimental Therapeutics.

[52]  R. Matucci,et al.  The direct stimulation of Gi proteins by neuropeptide Y (NPY) in the rat left ventricle. , 2002, Biochemical pharmacology.

[53]  G. Buzsáki,et al.  Action potential threshold of hippocampal pyramidal cells in vivo is increased by recent spiking activity , 2001, Neuroscience.

[54]  C. Saper,et al.  From Lesions to Leptin Hypothalamic Control of Food Intake and Body Weight , 1999, Neuron.

[55]  S. Whitebread,et al.  A receptor subtype involved in neuropeptide-Y-induced food intake , 1996, Nature.

[56]  David J. Anderson,et al.  Internal States and Behavioral Decision-Making: Toward an Integration of Emotion and Cognition. , 2014, Cold Spring Harbor symposia on quantitative biology.