Multiscale hierarchical mechanics in soft tissues

In this paper, the mechanics of soft tissues is modeled by introducing a novel polyconvex strain-energy function able to include tissue structured hierarchical arrangement and by reducing model complexity via multiscale homogenization techniques. The case of arterial tissue is successfully addressed by obtaining a quantitative prediction of the age-dependent alterations in aorta mechanics incorporating histological remodeling mechanisms and biochemical variations. (© 2015 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim)