Rapid assessment of visual function: an electronic sweep technique for the pattern visual evoked potential.

We have developed an electronic spatial frequency sweep technique for electrophysiological assessment of visual acuity and pattern vision. The technique allows an accurate and reliable measurement of VEPs to a full range of spatial frequencies in just 10 sec. Because the measurements are so rapid, the technique suggests several new improvements in the assessment of visual function. Sweeping spatial frequency linearly and extrapolating the high-frequency region of the VEP spatial-tuning function to zero voltage allows an estimate of acuity which correlates highly with psychophysical estimates of acuity. Variants of the procedure are appropriate for the assessment of refracture error, determination of equality of visual function for the two eyes and of binocular interactions, and for sequential assessment of therapeutic conditions.

[1]  F. Campbell,et al.  Electrophysiological evidence for the existence of orientation and size detectors in the human visual system , 1970, The Journal of physiology.

[2]  S. Sokol An electrodiagnostic index of macular degeneration. Use of a checkerboard pattern stimulus. , 1972, Archives of ophthalmology.

[3]  S. J. Fricker Narrow-band filter techniques for the detection and measurement of evoked responses. , 1962, Electroencephalography and clinical neurophysiology.

[4]  C Blakemore,et al.  On the existence of neurones in the human visual system selectively sensitive to the orientation and size of retinal images , 1969, The Journal of physiology.

[5]  M. R. Harter,et al.  Effects of contour sharpness and check-size on visually evoked cortical potentials. , 1968, Vision research.

[6]  D M Levi,et al.  Spatio-temporal interactions in anisometropic and strabismic amblyopia. , 1977, Investigative ophthalmology & visual science.

[7]  F. Campbell,et al.  Optical quality of the human eye , 1966, The Journal of physiology.

[8]  M Millodot,et al.  Refraction determined electrophysiologically. Responses to alternation of visual contours. , 1970, Archives of ophthalmology.

[9]  D Regan,et al.  Rapid objective refraction using evoked brain potentials. , 1973, Investigative ophthalmology.

[10]  Ivan Bodis-Wollner,et al.  Visual Acuity and Contrast Sensitivity in Patients with Cerebral Lesions , 1972, Science.

[11]  C. Tyler,et al.  Binocular interactions in the human visual evoked potential after short-term occlusion and anisometropia. , 1977, Investigative ophthalmology & visual science.

[12]  D M Levi,et al.  Contrast evoked potentials in strabismic and anisometropic amblyopia. , 1978, Investigative ophthalmology & visual science.

[13]  D. G. Green,et al.  Optical and retinal factors affecting visual resolution. , 1965, The Journal of physiology.

[14]  Variations in human cortical response to patterns and image quality. , 1972, Investigative ophthalmology.

[15]  E Marg,et al.  A reconsideration of visual evoked potentials for fast automated ophthalmic refractions. , 1978, Investigative ophthalmology & visual science.

[16]  S. Sokol,et al.  Measurement of infant visual acuity from pattern reversal evoked potentials , 1978, Vision Research.

[17]  P. Apkarian,et al.  Multiple spatial-frequency tuning of electrical responses from human visual cortex , 1978, Experimental Brain Research.

[18]  W. Mcdonald,et al.  Visual Evoked Response in Diagnosis of Multiple Sclerosis , 1973, British medical journal.

[19]  D. Regan Latencies of evoked potentials to flicker and to pattern speedily estimated by simultaneous stimulation method , 1976 .

[20]  J. Behrman The visual evoked response in hysterical amblyopia. , 1969, The British journal of ophthalmology.

[21]  D. Levi,et al.  HYSTERICAL AMBLYOPIA: ELECTRODIAGNOSTIC AND CLINICAL EVALUATION* , 1975, American journal of optometry and physiological optics.