The acute and sub-chronic exposures of goldfish to naphthenic acids induce different host defense responses.

[1]  M. Belosevic,et al.  Commercial naphthenic acids and the organic fraction of oil sands process water induce different effects on pro‐inflammatory gene expression and macrophage phagocytosis in mice , 2012, Journal of applied toxicology : JAT.

[2]  J. Stafford,et al.  Ozone treatment ameliorates oil sands process water toxicity to the mammalian immune system. , 2011, Water research.

[3]  M. Belosevic,et al.  Commercial naphthenic acids and the organic fraction of oil sands process water downregulate pro-inflammatory gene expression and macrophage antimicrobial responses. , 2011, Toxicology letters.

[4]  P. Fedorak,et al.  Distribution of naphthenic acids in tissues of laboratory-exposed fish and in wild fishes from near the Athabasca oil sands in Alberta, Canada. , 2011, Ecotoxicology and environmental safety.

[5]  M. Belosevic,et al.  Comparison of Macrophage Antimicrobial Responses Induced by Type II Interferons of the Goldfish (Carassius auratus L.)* , 2010, The Journal of Biological Chemistry.

[6]  M. Belosevic,et al.  Molecular characterization of novel interferon gamma receptor 1 isoforms in zebrafish (Danio rerio) and goldfish (Carassius auratus L.). , 2009, Molecular immunology.

[7]  M. Belosevic,et al.  Molecular characterization of tumor necrosis factor receptors 1 and 2 of the goldfish (Carassius aurutus L.). , 2009, Molecular immunology.

[8]  M. Belosevic,et al.  Molecular characterization, expression and functional analysis of goldfish (Carassius aurutus L.) interferon gamma. , 2009, Developmental and comparative immunology.

[9]  M. Belosevic,et al.  Transferrin-derived synthetic peptide induces highly conserved pro-inflammatory responses of macrophages. , 2009, Molecular immunology.

[10]  K. Solomon,et al.  Toxicity assessment of collected fractions from an extracted naphthenic acid mixture. , 2008, Chemosphere.

[11]  K. Peru,et al.  Comparison of high- and low-resolution electrospray ionization mass spectrometry for the analysis of naphthenic acid mixtures in oil sands process water. , 2008, Rapid communications in mass spectrometry : RCM.

[12]  Daniel W. Smith,et al.  Ozonation of oil sands process water removes naphthenic acids and toxicity. , 2008, Chemosphere.

[13]  D. Dixon,et al.  Effects of oil sands process-affected waters and naphthenic acids on yellow perch (Perca flavescens) and Japanese medaka (Orizias latipes) embryonic development. , 2007, Chemosphere.

[14]  D. Dixon,et al.  Gill and liver histopathological changes in yellow perch (Perca flavescens) and goldfish (Carassius auratus) exposed to oil sands process-affected water. , 2006, Ecotoxicology and environmental safety.

[15]  Chun Chi Lo,et al.  Mass spectrometric and toxicological assays of Athabasca oil sands naphthenic acids. , 2006, Water research.

[16]  M. Belosevic,et al.  Comparison of select innate immune mechanisms of fish and mammals , 2005, Xenotransplantation.

[17]  P. Fedorak,et al.  A review of the occurrence, analyses, toxicity, and biodegradation of naphthenic acids. , 2005, Chemosphere.

[18]  J. Headley,et al.  In Situ Bioremediation of Naphthenic Acids Contaminated Tailing Pond Waters in the Athabasca Oil Sands Region—Demonstrated Field Studies and Plausible Options: A Review , 2005, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.

[19]  J. Headley,et al.  A Review of the Occurrence and Fate of Naphthenic Acids in Aquatic Environments , 2004, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.

[20]  Jos H Beijnen,et al.  An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons. , 2003, Toxicology and applied pharmacology.

[21]  P. Fedorak,et al.  Characterization of naphthenic acids in oil sands wastewaters by gas chromatography-mass spectrometry. , 2002, Water research.

[22]  A. P. Kulkarni Role of biotransformation in conceptal toxicity of drugs and other chemicals. , 2001, Current pharmaceutical design.

[23]  D. Dixon,et al.  Disease and gill lesions in yellow perch (Perca flavescens) exposed to oil sands mining-associated waters. , 2000, Ecotoxicology and environmental safety.

[24]  G. Prud’homme Gene therapy of autoimmune diseases with vectors encoding regulatory cytokines or inflammatory cytokine inhibitors , 2000, The journal of gene medicine.

[25]  C. Ioannides,et al.  Cytochromes P450 and species differences in xenobiotic metabolism and activation of carcinogen. , 1998, Environmental health perspectives.

[26]  Y. Stierhof,et al.  Cultivation of bloodstream forms of Trypanosoma carassii, a common parasite of freshwater fish , 1998, Parasitology Research.

[27]  I. Dalsgaard,et al.  Occurrence and significance of atypical Aeromonas salmonicida in non-salmonid and salmonid fish species: a review. , 1998, Diseases of aquatic organisms.

[28]  M. Belosevic,et al.  Comparative assessment of growth of Trypanosoma danilewskyi (Laveran & Mesnil) in medium containing fish or mammalian serum , 1997 .

[29]  N. Neumann,et al.  Deactivation of primed respiratory burst response of goldfish macrophages by leukocyte-derived macrophage activating factor(s). , 1996, Developmental and comparative immunology.

[30]  J. Alcocer-Varela,et al.  Cytokine inhibitors in autoimmune disease. , 1996, Seminars in arthritis and rheumatism.

[31]  M. Belosevic,et al.  Estradiol increases susceptibility of goldfish to Trypanosoma danilewskyi. , 1994, Developmental and comparative immunology.

[32]  J. Costerton,et al.  Biodegradation of naphthenic acids by microbial populations indigenous to oil sands tailings. , 1994, Canadian journal of microbiology.

[33]  J. Schreurs Cytokines in infectious disease: the battle between host and pathogen. , 1993, Current opinion in biotechnology.

[34]  P. Miossec Acting on the cytokine balance to control auto-immunity and chronic inflammation. , 1993, European cytokine network.

[35]  F. Liew Role of cytokines in killing of intracellular pathogens. , 1991, Immunology letters.

[36]  R. Snyderman,et al.  Redistribution of protein kinase C activity in human monocytes: correlation with activation of the respiratory burst. , 1985, Journal of immunology.

[37]  J. Davis Distribution of naphthenic acids in an oil-bearing aquifer , 1969 .

[38]  H. Wong,et al.  Biotransformation and Bioactivation , 2011 .

[39]  M. Belosevic,et al.  Characterization and functional analysis of goldfish (Carassius auratus L.) tumor necrosis factor-alpha. , 2008, Developmental and comparative immunology.

[40]  N. Bunce,et al.  Preliminary risk assessment of the wet landscape option for reclamation of oil sands mine tailings: Bioassays with mature fine tailings pore water , 2001, Environmental toxicology.

[41]  K. Bendtzen Immune hormones (cytokines); pathogenic role in autoimmune rheumatic and endocrine diseases. , 1989, Autoimmunity.

[42]  J. DiGiovanni,et al.  Biotransformation and bioactivation of 7, 12-dimethylbenz[a]anthracene (7, 12-DMBA). , 1980, Drug metabolism reviews.