TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner

[1]  A. López-Rivas,et al.  ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2 , 2012, Apoptosis.

[2]  A. López-Rivas,et al.  ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2 , 2011, Apoptosis.

[3]  A. Strasser,et al.  Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells , 2011, The Journal of experimental medicine.

[4]  P. Bouillet,et al.  Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage , 2011, Cell Death and Disease.

[5]  B. Aggarwal,et al.  Gossypol Induces Death Receptor-5 through Activation of the ROS-ERK-CHOP Pathway and Sensitizes Colon Cancer Cells to TRAIL* , 2010, The Journal of Biological Chemistry.

[6]  C. Trautwein,et al.  Hepatocyte-specific NEMO deletion promotes NK/NKT cell– and TRAIL-dependent liver damage , 2009, The Journal of experimental medicine.

[7]  L. Pohl,et al.  Pathogenic role of natural killer T and natural killer cells in acetaminophen‐induced liver injury in mice is dependent on the presence of dimethyl sulfoxide , 2008, Hepatology.

[8]  G. Gores,et al.  TRAIL mediates liver injury by the innate immune system in the bile duct–ligated mouse , 2008, Hepatology.

[9]  H. Jaeschke,et al.  Mitochondrial Bax Translocation Accelerates DNA Fragmentation and Cell Necrosis in a Murine Model of Acetaminophen Hepatotoxicity , 2008, Journal of Pharmacology and Experimental Therapeutics.

[10]  Lieping Chen,et al.  Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7‐homolog 1‐dependent CD8+ T cell tolerance , 2007, Hepatology.

[11]  A. Strasser,et al.  The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest , 2007, Cell.

[12]  G. Nagy,et al.  Acetaminophen induces ER dependent signaling in mouse liver. , 2007, Archives of biochemistry and biophysics.

[13]  R. Flavell,et al.  Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure , 2006, Gut.

[14]  N. Kaplowitz,et al.  c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. , 2006, Gastroenterology.

[15]  H. Jaeschke,et al.  Peroxynitrite-Induced Mitochondrial and Endonuclease-Mediated Nuclear DNA Damage in Acetaminophen Hepatotoxicity , 2005, Journal of Pharmacology and Experimental Therapeutics.

[16]  R. McCuskey,et al.  Ethanol binging exacerbates sinusoidal endothelial and parenchymal injury elicited by acetaminophen. , 2005, Journal of hepatology.

[17]  Toshiharu Horie,et al.  Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice. , 2005, Journal of hepatology.

[18]  B. Rumack Acetaminophen misconceptions , 2004, Hepatology.

[19]  William M. Lee Acetaminophen and the U.S. acute liver failure study group: Lowering the risks of hepatic failure , 2004, Hepatology.

[20]  Yoshiya Ito,et al.  Early Hepatic Microvascular Injury in Response to Acetaminophen Toxicity , 2003, Microcirculation.

[21]  M. Crabtree,et al.  Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: roles of cytochrome c, Bax, Bid, and caspases. , 2003, Toxicology and applied pharmacology.

[22]  M. Smyth,et al.  Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells , 2001, Nature Medicine.

[23]  J. Peschon,et al.  IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression. , 1999, Journal of immunology.

[24]  N. Kaplowitz,et al.  Sinusoidal endothelial cells as a target for acetaminophen toxicity direct action versus requirement for hepatocyte activation in different mouse strains , 1997 .

[25]  P. Boros,et al.  Assessment of damage and recovery of sinusoidal endothelial cell function by in vivo hyaluronic acid uptake in cold-preserved and transplanted rat livers. , 1996, Transplantation.

[26]  N. Kaplowitz,et al.  Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease. , 1996, Hepatology.

[27]  P. O’Brien,et al.  Acetaminophen‐induced microvascular injury in the rat liver: Protection with misoprostol , 1995, Hepatology.

[28]  P. Burcham,et al.  Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes. , 1991, The Journal of biological chemistry.

[29]  F. Oesch,et al.  Rat liver endothelial and Kupffer cell-mediated mutagenicity of polycyclic aromatic hydrocarbons and aflatoxin B1. , 1990, Environmental health perspectives.

[30]  F. Oesch,et al.  Xenobiotic metabolizing enzymes are not restricted to parenchymal cells in rat liver. , 1987, Molecular pharmacology.

[31]  W. J. Racz,et al.  Scanning electron microscopic examination of acetaminophen-induced hepatotoxicity and congestion in mice. , 1983, The American journal of pathology.

[32]  C. Edgell,et al.  Permanent cell line expressing human factor VIII-related antigen established by hybridization. , 1983, Proceedings of the National Academy of Sciences of the United States of America.