A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
暂无分享,去创建一个
Marc W. Kirschner | Glenn D. Prestwich | Orion D. Weiner | Henry R. Bourne | Lewis C. Cantley | M. Kirschner | G. Prestwich | H. Bourne | L. Cantley | O. Weiner | Paul O. Neilsen
[1] W L Stanford,et al. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. , 2000, Science.
[2] Timothy J. Mitchison,et al. Spatial control of actin polymerization during neutrophil chemotaxis , 1999, Nature Cell Biology.
[3] T. Sasaki,et al. SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival. , 1999, Genes & development.
[4] J W Sedat,et al. Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis. , 1999, Molecular biology of the cell.
[5] J. Hartwig,et al. Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases. , 1997, Advances in enzyme regulation.
[6] Joseph C. Shope,et al. Intracellular delivery of phosphoinositides and inositol phosphates using polyamine carriers. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[7] P. Hawkins,et al. PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase , 1995, Current Biology.
[8] José Luis de la Pompa,et al. Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN , 1998, Cell.
[9] L. Cantley,et al. Rho Family GTPases Bind to Phosphoinositide Kinases (*) , 1995, The Journal of Biological Chemistry.
[10] D. Murphy,et al. Dynamic Distribution of Chemoattractant Receptors in Living Cells During Chemotaxis and Persistent Stimulation , 1997, The Journal of cell biology.
[11] E. Génot,et al. The T-Cell Receptor Regulates Akt (Protein Kinase B) via a Pathway Involving Rac1 and Phosphatidylinositide 3-Kinase , 2000, Molecular and Cellular Biology.
[12] Hui Ma,et al. Chemoattractant‐mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium , 1999, The EMBO journal.
[13] J W Sedat,et al. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. , 2000, Science.
[14] T. Meyer,et al. Spatial Sensing in Fibroblasts Mediated by 3′ Phosphoinositides , 2000, The Journal of cell biology.
[15] Silvano Sozzani,et al. Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation , 2000 .
[16] D. Williams,et al. Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells. , 2000, Immunity.
[17] M. Peter,et al. Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast. , 2000, Molecular cell.
[18] M. Waterfield,et al. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages , 1999, Nature Cell Biology.
[19] S. Bagrodia,et al. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. , 1994, The Journal of biological chemistry.
[20] G. Bokoch,et al. Rac GTPase interacts specifically with phosphatidylinositol 3-kinase. , 1996, The Biochemical journal.
[21] A. Toker,et al. The Lipid Products of Phosphoinositide 3-Kinase Increase Cell Motility through Protein Kinase C* , 1997, The Journal of Biological Chemistry.
[22] G. Bokoch,et al. Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases* , 1999, The Journal of Biological Chemistry.
[23] V. Niggli,et al. The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils. , 1997, European journal of pharmacology.
[24] C. Parent,et al. Localization of the G Protein βγ Complex in Living Cells During Chemotaxis , 2000 .
[25] Dianqing Wu,et al. Roles of PLC-β2 and -β3 and PI3Kγ in Chemoattractant-Mediated Signal Transduction , 2000 .
[26] V. Niggli,et al. A membrane‐permeant ester of phosphatidylinositol 3,4,5‐trisphosphate (PIP3) is an activator of human neutrophil migration , 2000, FEBS letters.
[27] H. Meinhardt,et al. Pattern formation by local self-activation and lateral inhibition. , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.
[28] Richard A. Firtel,et al. Role of Phosphatidylinositol 3′ Kinase and a Downstream Pleckstrin Homology Domain–Containing Protein in Controlling Chemotaxis inDictyostelium , 2001, The Journal of cell biology.
[29] R. Mamillapalli,et al. Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases , 2000, Current Biology.