Effect of phase difference in multi-antenna microwave thermal ablation for breast cancer treatment

It was realized that cancer in breast is one of the most health hazards threatening women around the world for many years. Thermal ablation by using microwave energy is another alternative surgical maneuver due to its minimally invasive therapeutic technique. In this research, we investigate an effect of phase difference between three adjacent openedslot coaxial probes in a multiple antenna alignment of microwave thermal ablation system for breast cancer treatment. FEM by using COMSOL is an implementation tools to simulate for 0, 45, 90, 135 and 180 degree of phase difference. 3D Simulation results show that temperature distribution pattern, destructive volume and SAR in breast tissue are affected from those phase-shift utilization in multi-antenna system significantly.

[1]  Christopher L Brace,et al.  Microwave tissue ablation: biophysics, technology, and applications. , 2010, Critical reviews in biomedical engineering.

[2]  L. Hutchinson,et al.  Breast cancer: Challenges, controversies, breakthroughs , 2010, Nature Reviews Clinical Oncology.

[3]  Christopher L Brace,et al.  Microwave tumor ablation: mechanism of action, clinical results, and devices. , 2010, Journal of vascular and interventional radiology : JVIR.

[4]  R. Pethig,et al.  Dielectric properties of body tissues. , 1987, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[5]  Z Zhao,et al.  Minimally-invasive thermal ablation of early-stage breast cancer: a systemic review. , 2010, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[6]  Pattarapong Phasukkit,et al.  Finite-Element Analysis and In Vitro Experiments of Placement Configurations Using Triple Antennas in Microwave Hepatic Ablation , 2009, IEEE Transactions on Biomedical Engineering.

[7]  C. Brace,et al.  Thermal Tumor Ablation in Clinical Use , 2011, IEEE Pulse.

[8]  R. Hwang,et al.  Ablative therapies of the breast. , 2011, Surgical oncology clinics of North America.

[9]  L. Leija,et al.  Microwave ablation for breast cancer using a microcoaxial antenna: Thermal comparison between swine breast tissue and breast phantom , 2011, 2011 Pan American Health Care Exchanges.

[10]  W. Mali,et al.  Minimally Invasive Ablative Therapies for Invasive Breast Carcinomas: An Overview of Current Literature , 2007, World Journal of Surgery.