Case study: accidental clonidine patch overdose in attention-deficit/hyperactivity disorder patients.

The safety and efficacy of the clonidine patch are contingent on the integrity of the transdermal system and the condition of the dermal surface to which it is applied. This article presents the first 2 case reports in the literature of unintentional overdose in pediatric patients with attention-deficit/hyperactivity disorder treated with transdermal clonidine. Appropriate precautions and patient education can help limit toxicity from the clonidine patch in children and adolescents.

[1]  W. King,et al.  Clonidine poisoning in Jefferson County, Alabama. , 1997, Annals of emergency medicine.

[2]  R. Tervo,et al.  Clonidine: a practical guide for usage in children. , 1996, South Dakota medicine : the journal of the South Dakota State Medical Association.

[3]  D. Rosenberg,et al.  Textbook of pharmacotherapy for child and adolescent psychiatric disorders , 1994 .

[4]  Fetrow Cw,et al.  Initiation of tricyclic treatment at full dose. , 1994 .

[5]  Chris M. Shinar,et al.  Clonidine Patch Ingestion in an Adult , 1993, The Annals of pharmacotherapy.

[6]  D. T. O'Connor,et al.  Skin pretreatment and the use of transdermal clonidine. , 1991, The American journal of medicine.

[7]  D. Willms.  Possible complications of acupuncture. , 1991, The Western journal of medicine.

[8]  J. M. Harris.  Clonidine Patch Toxicity , 1990, DICP : the annals of pharmacotherapy.

[9]  D. Fiser,et al.  Critical care for clonidine poisoning in toddlers. , 1990, Critical care medicine.

[10]  S. L. Richardson,et al.  Clonidine poisoning in children. , 1990, American journal of diseases of children.

[11]  F. Henretig,et al.  Clonidine poisoning in young children. , 1989, The Journal of pediatrics.

[12]  Hunt Rd.  Treatment effects of oral and transdermal clonidine in relation to methylphenidate: an open pilot study in ADD-H. , 1987 .