The Relationship between Maximal Urethral Closure Pressure and Functional Urethral Length in Anterior Vaginal Wall Prolapse Patients According to Stage and Age

MUCP (Maximal urethral closure pressure) is known to be increased in patients with vaginal wall prolapse due to the mechanical obstruction of the urethra. However, urethral function following reduction has not yet been completely elucidated. Predicting postoperative urethral function may provide patients with important, additional information prior to surgery. Thus, this study was performed to evaluate the relationship between MUCP and functional urethral length (FUL) according to stage and age in anterior vaginal wall prolapse patients. 139 patients diagnosed with anterior vaginal wall prolapse at Yonsei University Medical College (YUMC) from March 1999 to May 2003 who had underwent urethral pressure profilometry following reduction were included in this study. The stage of pelvic organ prolapse (POP) was determined according to the dependent portion of the anterior vaginal wall (Aa, Ba). (By International Continence Society's POP Quantification system) Patients were divided into one of four age groups: patients in their 40s (n=13), 50s (n=53), 60s (n=54), and 70 and over (n=16). No difference in MUCP was found between the age groups. The FUL of patients in their 40s was shorter than that of patient's in their 50s and 60s. Patients were also divided into stages: stage II (n=35), stage III (n=76), and stage IV (n=25). No significant difference in MUCP was found according to stage and FUL. However, a significant difference was noted between stage III and IV as stage IV was longer. Anterior vaginal wall prolapse is known to affect urethral function due to prolapse itself, but according to our study, prolapse itself did not alter urethral function. This suggests that, regardless of age and stage, prolapse corrective surgery does not affect the urethral function.

[1]  S L Stanton,et al.  The standardisation of terminology of lower urinary tract function , 1989, World Journal of Urology.

[2]  S. Bai,et al.  The effect of pelvic organ prolapse on lower urinary tract function. , 2003, Yonsei medical journal.

[3]  H. Koelbl,et al.  Computer‐Assisted Virtual Urethral Pressure Profile in the Assessment of Female Genuine Stress Incontinence , 2002, Obstetrics and gynecology.

[4]  H. Dietz,et al.  Female Pelvic Organ Prolapse and Voiding Function , 2002, International Urogynecology Journal.

[5]  A. Groutz,et al.  Evaluation of female lower urinary tract symptoms: overview and update , 2001, Current opinion in obstetrics & gynecology.

[6]  K. Luber,et al.  The demographics of pelvic floor disorders: current observations and future projections. , 2001, American journal of obstetrics and gynecology.

[7]  H. Kuo The Relationships of Urethral and Pelvic Floor Muscles and the Urethral Pressure Measurements in Women with Stress Urinary Incontinence , 2000, European Urology.

[8]  J. Blaivas,et al.  Predicting the need for anti-incontinence surgery in continent women undergoing repair of severe urogenital prolapse. , 2000, The Journal of urology.

[9]  D. Santini,et al.  A histological and immunohistochemical study of neuropeptide containing somatic nerves in the levator animuscle of women with genitourinary prolapse , 1999, Acta obstetricia et gynecologica Scandinavica.

[10]  D. Myers,et al.  The Effect of Posterior Wall Support Defects on Urodynamic Indices in Stress Urinary Incontinence , 1998, Obstetrics and gynecology.

[11]  Jonathan S. Berek,et al.  Novak's Gynecology , 1996 .

[12]  L. Brubaker,et al.  The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. , 1996, American journal of obstetrics and gynecology.

[13]  N. Bhatia,et al.  Prevalence of Abnormal Urodynamic Test Results in Continent Women With Severe Genitourinary Prolapse , 1992, Obstetrics and gynecology.

[14]  Fantl Ja,et al.  The mechanism of urinary continence in women with severe uterovaginal prolapse: results of barrier studies. , 1988 .

[15]  W. Hurt,et al.  The mechanism of urinary continence in women with severe uterovaginal prolapse: Results of barrier studies , 1988, Obstetrics and gynecology.

[16]  M. Swash,et al.  Perineal nerve damage in genuine stress urinary incontinence. An electrophysiological study. , 1985, British journal of urology.

[17]  D. Richardson,et al.  The effect of uterovaginal prolapse on urethrovesical pressure dynamics. , 1983, American journal of obstetrics and gynecology.

[18]  S. Stanton,et al.  Voiding Difficulties in the Female: Prevalence, Clinical and Urodynamic Review , 1983, Obstetrics and gynecology.

[19]  Raymond A. Lee Te Linde's Operative gynecology , 2019 .

[20]  D. Rowan,et al.  The standardization of terminology of lower urinary tract function , 1990, British journal of obstetrics and gynaecology.