Selenium balance in patients suffering from psoriasis vulgaris in different development phases Part 1. Concentration of selenium in selected morphotic components and excreta and activity of glutation peroxidase in red blood cells

There was taken the correlation analysis of dependence of selenium concentration in red blood cells, plasma, urine, hair and nails and the activity of glutation peroxidase in red blood cells on psoriasis clinical parameters: age at beginning of disease, duration of disease, duration of last clinical recurrence, duration of last clinical remission, skin surface displaying clinical changes and area and severity of skin changes (PASI). The significant inverted correlation between concentration of selenium in red blood cells and plasma and value of PASI indicator has been confirmed.

[1]  J. Hunter,et al.  Differential expression of selenoproteins by human skin cells and protection by selenium from UVB-radiation-induced cell death. , 1998, The Biochemical journal.

[2]  N. Kettaneh-Wold,et al.  Clinical and biological effects of balneotherapy with selenium‐rich spa water in patients with psoriasis vulgaris , 1995, The British journal of dermatology.

[3]  A. Naukkarinen,et al.  Screening of effects of selenomethionine-enriched yeast supplementation on various immunological and chemical parameters of skin and blood in psoriatic patients. , 1993, Acta dermato-venereologica.

[4]  R. Goldbohm,et al.  Predictors of toenail selenium levels in men and women. , 1993, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[5]  C. Minoia,et al.  Selenium plasma levels in psoriasis , 1992, Clinical and experimental dermatology.

[6]  B. Clayton,et al.  The Effect of Supplementation with Selenium and Vitamin E in Psoriasis , 1989, Annals of clinical biochemistry.

[7]  B. Berne,et al.  Selenium in whole blood and plasma is decreased in patients with moderate and severe psoriasis. , 1989, Acta dermato-venereologica.

[8]  B. Clayton,et al.  Trace element status in eczema and psoriasis , 1987, Clinical and experimental dermatology.

[9]  T Fredriksson,et al.  Severe psoriasis--oral therapy with a new retinoid. , 1978, Dermatologica.

[10]  P. Wester,et al.  The estimated daily loss of trace elements from normal skin by desquamation. , 1976, Scandinavian journal of clinical and laboratory investigation.

[11]  B. Portnoy,et al.  Neutron activation analysis of trace elements in skin , 1973 .

[12]  H. Ganther,et al.  Selenium: Biochemical Role as a Component of Glutathione Peroxidase , 1973, Science.