Hypofractionated stereotactic radiation therapy activates the peripheral immune response in operable stage I non-small-cell lung cancer

[1]  C. Bert,et al.  Hypofractionated Irradiation Has Immune Stimulatory Potential and Induces a Timely Restricted Infiltration of Immune Cells in Colon Cancer Tumors , 2017, Front. Immunol..

[2]  Yang Zhang,et al.  Effect of EBI3 on radiation-induced immunosuppression of cervical cancer HeLa cells by regulating Treg cells through PD-1/PD-L1 pathway , 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

[3]  S. H. van der Burg,et al.  Impact of (chemo)radiotherapy on immune cell composition and function in cervical cancer patients , 2016, Oncoimmunology.

[4]  R. Başar,et al.  IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation. , 2016, Blood.

[5]  Joe Y. Chang,et al.  Immunotherapy and stereotactic ablative radiotherapy (ISABR): a curative approach? , 2016, Nature Reviews Clinical Oncology.

[6]  R. Fietkau,et al.  Development of a Modular Assay for Detailed Immunophenotyping of Peripheral Human Whole Blood Samples by Multicolor Flow Cytometry , 2016, International journal of molecular sciences.

[7]  Weiyang Jin,et al.  Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing , 2016, Cell.

[8]  Ji Luo,et al.  NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis , 2016, Nature.

[9]  S. Demaria,et al.  Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial. , 2015, The Lancet. Oncology.

[10]  Kevin J. Harrington,et al.  The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence , 2015, Nature Reviews Cancer.

[11]  Peter Balter,et al.  Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials. , 2015, The Lancet. Oncology.

[12]  A. Ng,et al.  A systematic evaluation of abscopal responses following radiotherapy in patients with metastatic melanoma treated with ipilimumab , 2015, Oncoimmunology.

[13]  James C. Whisstock,et al.  Perforin and granzymes: function, dysfunction and human pathology , 2015, Nature Reviews Immunology.

[14]  M. V. D. van den Brink,et al.  Interleukin-22: immunobiology and pathology. , 2015, Annual review of immunology.

[15]  Fumito Ito,et al.  Antitumor effector B cells directly kill tumor cells via the Fas/FasL pathway and are regulated by IL‐10 , 2015, European journal of immunology.

[16]  H. Ishwaran,et al.  Radiation and Dual Checkpoint Blockade Activates Non-Redundant Immune Mechanisms in Cancer , 2015, Nature.

[17]  B. Dörken,et al.  Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT. , 2014, Blood.

[18]  L. Coussens,et al.  B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas. , 2014, Cancer cell.

[19]  S. Rosenberg,et al.  Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer , 2014, Science.

[20]  J. Galon,et al.  Imaging , Diagnosis , Prognosis Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer , 2014 .

[21]  V. Khoo,et al.  Radiotherapy for renal-cell carcinoma. , 2014, The Lancet. Oncology.

[22]  R. Roden,et al.  Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors , 2013, Clinical Cancer Research.

[23]  K. Schäkel,et al.  Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy. , 2013, Cancer cell.

[24]  C. Belka,et al.  Current concepts in clinical radiation oncology , 2013, Radiation and environmental biophysics.

[25]  C. June,et al.  Radiation and immunotherapy: a synergistic combination. , 2013, The Journal of clinical investigation.

[26]  D. Jaffray Image-guided radiotherapy: from current concept to future perspectives , 2012, Nature Reviews Clinical Oncology.

[27]  K. Iwamoto,et al.  Maximizing tumor immunity with fractionated radiation. , 2012, International journal of radiation oncology, biology, physics.

[28]  Jedd D. Wolchok,et al.  Immunologic correlates of the abscopal effect in a patient with melanoma. , 2012, The New England journal of medicine.

[29]  N. Kawashima,et al.  Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody , 2009, Clinical Cancer Research.

[30]  R. Weichselbaum,et al.  Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. , 2009, Blood.

[31]  N. Kawashima,et al.  Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells1 , 2008, The Journal of Immunology.

[32]  Jianhong Cao,et al.  Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. , 2008, The New England journal of medicine.

[33]  Laurence Zitvogel,et al.  Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy , 2007, Nature Medicine.

[34]  I. Lax,et al.  Regression of non-irradiated metastases after extracranial stereotactic radiotherapy in metastatic renal cell carcinoma , 2006, Acta oncologica.

[35]  J. Massagué,et al.  TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. , 2005, Cancer cell.

[36]  Mary Helen Barcellos-Hoff,et al.  Radiation and the microenvironment – tumorigenesis and therapy , 2005, Nature Reviews Cancer.

[37]  George Coukos,et al.  Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival , 2004, Nature Medicine.

[38]  A. Horwich,et al.  Metastatic seminoma treated with either single agent carboplatin or cisplatin-based combination chemotherapy: a pooled analysis of two randomised trials , 2004, British Journal of Cancer.

[39]  S. Heisterkamp,et al.  Effect of preoperative oral immune-enhancing nutritional supplement on patients at high risk of infection after cardiac surgery: a randomised placebo-controlled trial , 2001, The Lancet.

[40]  K. Omagari,et al.  Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis , 1998, Gut.

[41]  J. Le Bourgeois,et al.  [Whole body irradiation]. , 1989, Pathologie-biologie.

[42]  D. Kingsley An interesting case of possible abscopal effect in malignant melanoma. , 1975, The British journal of radiology.

[43]  Mole Rh Whole body irradiation; radiobiology or medicine? , 1953 .

[44]  G. Coukos,et al.  Radiotherapy combination opportunities leveraging immunity for the next oncology practice , 2017, CA: a cancer journal for clinicians.

[45]  S. Hampson Randomised, placebo-controlled trial , 2002 .

[46]  M. Fingerman,et al.  Immunobiology and pathology , 2000 .

[47]  R. Mole Whole body irradiation; radiobiology or medicine? , 1953, The British journal of radiology.