Effect of Actinospectacin (Trobicin) in Experimental Syphilis in the Rabbit—II

The broad-spectrum antibiotic actinospectacint may have general application in human therapy. Its effectiveness in the treatment of gonorrhoea has been reported by Willcox (1962) and by Laird and Taylor (1962). Earlier studies in this laboratory demonstrated its effect in experimental early lesion syphilis in the rabbit (Clark and Yobs, 1963). Patients with symptomatic gonorrhoea may also have inapparent incubating syphilis. This is a report of the effects of actinospectacin at the dosage level used in gonorrhoea and other human infections in subclinical incubating syphilis in the rabbit.

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[2]  R. Petersdorf,et al.  AN EVALUATION OF A NEW ANTIBIOTIC, ACTINOSPECTACIN, IN INFECTIONS OF THE URINARY TRACT* , 1962, The American journal of the medical sciences.

[3]  R. Willcox..  Trobicin (Actinospectacin). A New Injectable Antibiotic in the Treatment of Gonorrhoea* , 1962, The British journal of venereal diseases.

[4]  H. J. Magnuson,et al.  INOCULATION SYPHILIS IN HUMAN VOLUNTEERS , 1956, Medicine.