Constructing the Architecturally Distinctive ABD-Tricycle of Phomactin A through an Intramolecular Oxa-[3 + 3] Annulation Strategy.
暂无分享,去创建一个
R. Hsung | K. P. Cole | Lingfeng You | Yu Tang | G. S. Buchanan | Gang Li
[1] R. Hsung,et al. Total synthesis of (±)-phomactin A. Lessons learned from respecting a challenging structural topology. , 2011, The Journal of organic chemistry.
[2] Guangyan Du,et al. Construction of the tricyclic furanochroman skeleton of phomactin A via the Prins/Conia-ene cascade cyclization approach. , 2011, The Journal of organic chemistry.
[3] M. Hirama,et al. Total synthesis of cortistatins A and J. , 2011, The Journal of organic chemistry.
[4] James D White,et al. Synthesis of the cyclohexane core of phomactins and a new route to the bicyclo[9.3.1]pentadecane diterpenoid skeleton. , 2011, Organic letters.
[5] K. Tatsuta,et al. The first total synthesis and structural determination of epi-cochlioquinone A , 2010 .
[6] R. Hsung,et al. Aza-[3 + 3] Annulations: A New Unified Strategy in Alkaloid Synthesis. , 2010, Current organic synthesis.
[7] A. Frontier,et al. Beta-iodoallenolates as springboards for annulation reactions. , 2009, Organic letters.
[8] E. J. Thomas,et al. Synthesis of precursors of phomactins using [2,3]-Wittig rearrangements , 2009 .
[9] R. Hsung,et al. Total synthesis of phomactin A. , 2009, Organic letters.
[10] K. Nicolaou,et al. Total Synthesis of Tovophyllin B. , 2009, Tetrahedron letters.
[11] Yoshihiko Yamamoto,et al. Synthesis of chromans via [3 + 3] cyclocoupling of phenols with allylic alcohols using a Mo/o-chloranil catalyst system. , 2009, Organic letters.
[12] Jongmin Park,et al. Diastereoselective synthesis of polycyclic acetal-fused pyrano[3,2-c]pyran-5(2H)-one derivatives. , 2009, The Journal of organic chemistry.
[13] Aaron A. Bedermann,et al. An Enantioselective Synthesis of the ABD Tricycle for (-)-Phomactin A Featuring Rawal's Asymmetric Diels-Alder Cycloaddition. , 2008, Advanced synthesis & catalysis.
[14] M. Hirama,et al. A concise synthesis of the pentacyclic framework of cortistatins. , 2008, Organic letters.
[15] Q. Wei,et al. Organocatalytic Asymmetric Formal [3+3] Cycloaddition Reactions of α,β‐Unsaturated Aldehydes with Nazarov Reagents , 2008 .
[16] I. Yavari,et al. Proline-Promoted Efficient Synthesis of 4-Aryl-3,4-dihydro-2H,5H-pyrano[3,2-c]chromene-2,5-diones in Aqueous Media , 2008 .
[17] J. P. Harrity,et al. Investigation of an organomagnesium-based [3 + 3] annelation to pyrans and its application in the synthesis of rhopaloic acid A. , 2008, The Journal of organic chemistry.
[18] J. Renaud,et al. Brønsted Acid‐Catalyzed Synthesis of Pyrans via a Formal [3+3] Cycloaddition , 2008 .
[19] Jie Huang,et al. Total synthesis of (+/-)-phomactin B2 via an intramolecular cyclohexadienone annulation of a chromium carbene complex. , 2007, Journal of the American Chemical Society.
[20] Y. R. Lee,et al. Concise Total Synthesis of Biologically Interesting Pyranochalcone Natural Products: Citrunobin, Boesenbergin A, Boesenbergin B, Xanthohumol C, and Glabrachromene , 2007 .
[21] J. P. Harrity,et al. A [3 + 3] annelation approach to (+)-rhopaloic acid B. , 2007, Organic letters.
[22] Hao Zhou,et al. Total synthesis of the opioid agonistic indole alkaloid mitragynine and the first total syntheses of 9-methoxygeissoschizol and 9-methoxy-Nb-methylgeissoschizol. , 2007, Organic letters.
[23] Dawei Teng,et al. Studies toward the synthesis of phomactin A. An approach to the macrocyclic core. , 2007, Tetrahedron letters.
[24] Jie Huang,et al. Intramolecular cyclohexadienone annulations of Fischer carbene complexes: model studies for the synthesis of Phomactins. , 2007, Organic letters.
[25] Dirk Trauner,et al. Biomimetic Synthesis of Antimalarial Naphthoquinones. , 2007, Journal of the American Chemical Society.
[26] T. Rovis,et al. A Sakurai-Prins-Ritter sequence for the three-component diastereoselective synthesis of 4-amino tetrahydropyrans. , 2006, Journal of the American Chemical Society.
[27] R. Hsung,et al. Strategies and Approaches for Constructing 1-Oxadecalins , 2006 .
[28] K C Nicolaou,et al. Cascade reactions in total synthesis. , 2006, Angewandte Chemie.
[29] C. Cho,et al. Regioselective Pd-catalyzed synthesis and application of 3-methyl-5-bromo-2-pyrone toward keto-phomactin A. , 2006, Organic letters.
[30] V. Puranik,et al. Facile synthesis of 1,3,7-trihydroxyxanthone and its regioselective coupling reactions with prenal: simple and efficient access to osajaxanthone and nigrolineaxanthone F. , 2006, The Journal of organic chemistry.
[31] R. Hsung,et al. An unusual cationic [2 + 2] cycloaddition in a divergent total synthesis of hongoquercin A and rhododaurichromanic acid A. , 2006, Journal of the American Chemical Society.
[32] W. Goldring,et al. The phomactins. A novel group of terpenoid platelet activating factor antagonists related biogenetically to the taxanes. , 2006, Accounts of chemical research.
[33] D. Siegel,et al. Studies directed toward the synthesis of terreulactone A: rapid construction of the A, B, C rings. , 2006, Organic letters.
[34] M. R. Islami,et al. A Convenient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5(6H)-dione and 2H,5H-Pyrano[3,2-c]chromene-2,5-dione Derivatives , 2006 .
[35] R. Hsung,et al. A Lewis Acid-Catalyzed Formal [3 + 3] Cycloaddition of α,β-Unsaturated Aldehydes with 4-Hydroxy-2-Pyrone, Diketones, and Vinylogous Esters , 2006 .
[36] Dirk Trauner,et al. Biosynthetic and biomimetic electrocyclizations. , 2005, Chemical reviews.
[37] R. Hsung,et al. Unique structural topology and reactivities of the ABD tricycle in phomactin A. , 2005, Chemical communications.
[38] J. P. Harrity,et al. [3 + 3] Cycloadditions and related strategies in alkaloid natural product synthesis. , 2005, Organic & biomolecular chemistry.
[39] R. Hsung,et al. A Formal [3 + 3] Cycloaddition Approach to Natural-Product Synthesis , 2005 .
[40] Y. R. Lee,et al. Concise synthesis of biologically interesting (′)-cannabichromene, (′)-cannabichromenic acid, and (′)-daurichromenic acid , 2005 .
[41] T. Constantieux,et al. Utilisation of 1,3‐Dicarbonyl Derivatives in Multicomponent Reactions , 2004 .
[42] T. Sugita,et al. Phomactin H, a novel diterpene from an unidentified marine-derived fungus , 2004 .
[43] S. Ōmura,et al. Absolute stereochemistries and total synthesis of (+)-arisugacins A and B, potent, orally bioactive and selective inhibitors of acetylcholinesterase , 2004 .
[44] H. Oikawa,et al. Biosynthesis of phomactins: common intermediate phomactatriene and taxadiene. , 2004, Chemical communications.
[45] P. D. Wilson,et al. A modular and concise total synthesis of (+/-)-daurichromenic acid and analogues. , 2004, The Journal of organic chemistry.
[46] W. Goldring,et al. Total synthesis of (+/-)-phomactin G, a platelet activating factor antagonist from the marine fungus Phoma sp. , 2004, Organic & biomolecular chemistry.
[47] R. Hsung,et al. Intramolecular formal oxa-[3 + 3] cycloaddition approach to the ABD system of phomactin A. , 2003, Organic letters.
[48] C. Hayes,et al. Synthetic studies towards the phomactins. Concise syntheses of the tricyclic furanochroman and the oxygenated bicyclo[9.3.1]pentadecane ring systems in phomactin A. , 2003, Organic & biomolecular chemistry.
[49] W. Goldring,et al. Synthetic studies towards congeners of phomactin A. Re-examination of the structure of Sch 49028. , 2003, Chemical communications.
[50] V. Rawal,et al. Structural determinants of blockade of eosinophil activation, adhesion and secretion by synthetic analogs of phomactin. , 2003, Life sciences.
[51] R. Hsung,et al. Formal [3 + 3] cycloaddition approach to chromenes and chromanes. Concise total syntheses of (+/-)-rhododaurichromanic acids A and B and methyl (+/-)-daurichromenic ester. , 2003, Organic letters.
[52] D. Trauner,et al. Biomimetic synthesis of (+/-)-pinnatal and (+/-)-sterekunthal A. , 2003, Journal of the American Chemical Society.
[53] E. J. Thomas,et al. Approaches to the total synthesis of phomactins , 2003 .
[54] Tamsyn Montagnon,et al. Tandem reactions, cascade sequences, and biomimetic strategies in total synthesis. , 2003, Chemical communications.
[55] R. Hsung,et al. A Formal [3 + 3] Cycloaddition Reaction. Improved Reactivity Using α,β-Unsaturated Iminium Salts and Evidence for Reversibility of 6π-Electron Electrocyclic Ring Closure of 1-Oxatrienes , 2003 .
[56] R. Halcomb,et al. Total synthesis of (+)-phomactin a using a B-alkyl Suzuki macrocyclization. , 2003, Journal of the American Chemical Society.
[57] G. Zimmerman,et al. Platelet-Activating Factor, a Pleiotrophic Mediator of Physiological and Pathological Processes , 2003, Critical reviews in clinical laboratory sciences.
[58] W. Goldring,et al. A total synthesis of (+/-)-phomactin A. , 2002, Organic & biomolecular chemistry.
[59] W. Goldring,et al. A total synthesis of phomactin A. , 2003, Chemical communications.
[60] S. Kozmin,et al. Preparation of (E)‐1‐Dimethylamino‐3‐tert‐Butyldimethylsiloxy‐1,3‐Butadiene , 2003 .
[61] R. Hsung,et al. The first enantioselective total synthesis of (-)-arisugacin A , 2002 .
[62] R. Halcomb,et al. Convergent enantioselective synthesis of the tricyclic core of phomactin A. , 2002, Organic letters.
[63] T. Iwama,et al. Design and development of highly effective Lewis acid catalysts for enantioselective Diels-Alder reactions. , 2002, Journal of the American Chemical Society.
[64] R. Hsung,et al. The total synthesis of (±)-arisugacin A☆ , 2002 .
[65] T. Iwama,et al. An efficient approach to Aspidosperma alkaloids via [4 + 2] cycloadditions of aminosiloxydienes: stereocontrolled total synthesis of (+/-)-tabersonine. Gram-scale catalytic asymmetric syntheses of (+)-tabersonine and (+)-16-methoxytabersonine. Asymmetric syntheses of (+)-aspidospermidine and (-)-que , 2002, Journal of the American Chemical Society.
[66] T. Iwama,et al. Broadly effective enantioselective Diels-Alder reactions of 1-amino-substituted-1,3-butadienes. , 2002, Organic letters.
[67] S. Ōmura,et al. The first total synthesis of (+/-)-arisugacin A, a potent, orally bioavailable inhibitor of acetylcholinesterase. , 2002, Organic letters.
[68] E. Butkus. Stereocontrolled Synthesis and Reactions of Bicyclo[3.3.1]nonanes , 2002 .
[69] V. Rawal,et al. Efficient assembly of the phomactin core via two different macrocyclization protocols. , 2001, Organic letters.
[70] S. Danishefsky,et al. Enantioselective synthesis of the oxadecalin core of phomactin A via a highly stereoselective Diels-Alder reaction. , 2001, Organic letters.
[71] R. Maleczka,et al. A Nozaki-Hiyama-Kishi Ni(II)/Cr(II) coupling approach to the phomactins. , 2001, Organic letters.
[72] R. Hsung,et al. Total syntheses of pyranoquinoline alkaloids: simulenoline, huajiaosimuline, and (+/-)-7-demethoxyzanthodioline. , 2001, The Journal of organic chemistry.
[73] R. Hsung,et al. A Concise Stereoselective Route to the Pentacyclic Frameworks of Arisugacin A and Territrem B. , 2000, Angewandte Chemie.
[74] Yong Huang,et al. Highly Enantioselective Diels−Alder Reactions of 1-Amino-3-siloxy-dienes Catalyzed by Cr(III)-Salen Complexes , 2000 .
[75] S. Danishefsky,et al. Transannular macrocyclization via intramolecular B-alkyl Suzuki reaction. , 2000, Organic letters.
[76] P. Seth,et al. Studies toward the tricyclic core of phomactin A. Synthesis of the reduced furanochroman subunit. , 2000, Organic letters.
[77] R. Halcomb,et al. Synthesis of the ring system of phomactin D using a Suzuki macrocyclization. , 2000, Organic letters.
[78] P. Seth,et al. Synthesis of 1-Oxadecalones via the Lewis Acid Catalyzed Dihydropyrone Diels−Alder Reaction , 1999 .
[79] Y. Ouchi,et al. Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice. , 1999, The Journal of clinical investigation.
[80] Michael T. Green,et al. ON THE REACTIVITY OF 1-AMINO-3-SILOXY-1,3-DIENES : KINETICS INVESTIGATION AND THEORETICAL INTERPRETATION , 1999 .
[81] R. Hsung,et al. Formal Cycloaddition Reactions of Vinylogous Amides with α,β-Unsaturated Iminiums. A Strategy for Constructing Piperidinyl Heterocycles , 1999 .
[82] Junquan Wang,et al. Dihydropyrones as Dienophiles in the Diels-Alder Reaction: Application to the Synthesis of 1-Oxadecalones. , 1999, The Journal of organic chemistry.
[83] R. Hsung,et al. Sequential 1,2-Addition−Electrocyclic Ring Closures Involving Acyclic α,β-Unsaturated Iminiums: A Formal [3 + 3] Cycloaddition Strategy to Unique Pyranyl Spirocycles , 1999 .
[84] Jean Rodriguez,et al. Synthesis of Functionalized Bicyclo[3.2.1]octanes and Their Multiple Uses in Organic Chemistry. , 1999, Chemical reviews.
[85] M. Sugano,et al. Structure-activity relationships of phomactin derivatives as platelet activating factor antagonists. , 1996, Journal of medicinal chemistry.
[86] H. Miyaoka,et al. Total synthesis of phomactin D , 1996 .
[87] C. Hayes,et al. Synthetic studies towards phomactin A. Concise synthesis of the novel tricyclic furanochroman system , 1996 .
[88] T. Hata,et al. Phomactin E, F, and G: new phomactin-group PAF antagonists from a marine fungus Phoma sp. , 1995, The Journal of antibiotics.
[89] R. Faure,et al. One-Pot Base-Promoted Tandem Michael Addition-Intramolecular Aldolization. Stereoselective Synthesis and Reactivity of 2-Hydroxybicyclo[3.2.1]octan-8-ones , 1995 .
[90] T. Hata,et al. Phomactins, Novel PAF Antagonists from Marine Fungus Phoma sp. , 1994 .
[91] U. Pindur,et al. Pericyclic key reactions in biological systems and biomimetic syntheses , 1994 .
[92] T. Lindberg. Strategies and Tactics in Organic Synthesis , 1993 .
[93] W. R. Bishop,et al. A novel class of platelet activating factor antagonists from Phoma sp. , 1993, The Journal of antibiotics.
[94] L. Tietze,et al. Sequential Transformations in Organic Chemistry: A Synthetic Strategy with a Future† , 1993 .
[95] A. McPhail,et al. Sch 47918: A novel PAF antagonist from the fungus Phoma sp , 1992 .
[96] T. Hata,et al. Phomactin A; a novel PAF antagonist from a marine fungus Phoma sp , 1991 .
[97] G. Palmisano,et al. The chemistry of coumarin derivatives, part 2. Reaction of 4-hydroxycoumarin with α,β-unsaturated aldehydes† , 1990 .
[98] D. Seebach,et al. [3 + 3]-Carbocyclizations of nitroallylic esters and enamines with stereoselective formation of up to six new stereogenic centers , 1990 .
[99] L. Tietze. Domino‐reactions: The tandem‐knoevenagel‐hetero‐diels‐alder reaction and its application in natural product synthesis , 1990 .
[100] L. Touqui,et al. Perspectives in platelet-activating factor research. , 1987, Pharmacological reviews.
[101] W. Price,et al. Total synthesis of isoflavones: jamaicin, calopogonium isoflavone-B, pseudobaptigenin, and maxima substance-B. Friedel-Crafts acylation reactions with acid-sensitive substrates , 1987 .
[102] K. Shishido,et al. Tandem electrocyclic-sigmatropic reaction of benzocyclobutenes. 21. A new route to isochroman-3-one-4-spiro-1′-cycloalk-3′-enes , 1986 .
[103] K. Shishido,et al. Tandem electrocyclic-sigmatropic reaction of benzocyclobutenes. An expedient route to 4,4-disubstituted isochromanones , 1985 .
[104] P. March,et al. The reactivity of 4‐hydroxy‐6‐methyl‐2‐pyrone towards different types of ketones , 1984 .
[105] P. March,et al. The reactivity of 4-hydroxy-6-methyl-2-pyrone towards aliphatic saturated and α,β-unsaturated aldehydes , 1984 .
[106] E. Marvell. Thermal electrocyclic reactions , 1980 .
[107] E. Corey,et al. A key intermediate for the synthesis of maytansine and related antitumor agents , 1978 .
[108] A. Groot,et al. A simple synthesis of 2h-pyrans; A one-step synthesis of flindersine , 1975 .
[109] M. Schlosser,et al. Selektive Synthesen mit Organometallen III. (Z)‐Crotylalkoholate mit metalltragenden olefinischen Kohlenstoffatomen , 1974 .
[110] G. Stork,et al. A NEW RING ENLARGEMENT SEQUENCE , 1956 .
[111] M. A. Stahmann,et al. Studies on 4-Hydroxycoumarins. V. The Condensation of α,β-Unsaturated Ketones with 4-Hydroxycoumarin1 , 1944 .