The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis
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Walter Birchmeier | Annalen Bleckmann | F. Brembeck | W. Birchmeier | A. Bleckmann | M. Wiese | Nathalie Zatula | Maria Wiese | Jens Bunzendahl | Christina Perske | Felix H. Brembeck | C. Perske | Nathalie Zatula | Jens Bunzendahl
[1] Hans Clevers,et al. Wnt/β-Catenin Signaling and Disease , 2012, Cell.
[2] Kenny Q. Ye,et al. Novel patterns of genome rearrangement and their association with survival in breast cancer. , 2006, Genome research.
[3] R. Cardiff,et al. Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[4] T. Akiyama,et al. Immunohistochemical expression of the β‐catenin‐interacting protein B9L is associated with histological high nuclear grade and immunohistochemical ErbB2/HER‐2 expression in breast cancers , 2007, Cancer science.
[5] W. Remmele,et al. [Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]. , 1987, Der Pathologe.
[6] Harold E. Varmus,et al. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome , 1982, Cell.
[7] A. Leong,et al. The Changing Role of Pathology in Breast Cancer Diagnosis and Treatment , 2011, Pathobiology.
[8] K. Grandien. Determination of transcription start sites in the human estrogen receptor gene and identification of a novel, tissue-specific, estrogen receptor-mRNA isoform , 1996, Molecular and Cellular Endocrinology.
[9] Walter Birchmeier,et al. Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. , 2006, Current opinion in genetics & development.
[10] J. Gustafsson,et al. The estrogen receptor gene: promoter organization and expression. , 1997, The international journal of biochemistry & cell biology.
[11] M. Bienz,et al. The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells , 2008, BMC Cancer.
[12] J. Bartek,et al. Keratin 19 expression in the adult and developing human mammary gland , 1990, The Histochemical Journal.
[13] K. Basler,et al. Focus Review The many faces and functions of b-catenin , 2012 .
[14] K. Brennan,et al. Wnt Proteins in Mammary Development and Cancer , 2004, Journal of Mammary Gland Biology and Neoplasia.
[15] R. Moll,et al. CD34+ fibrocytes in invasive ductal carcinoma, ductal carcinoma in situ, and benign breast lesions , 2002, Virchows Archiv.
[16] F. Gannon,et al. Human estrogen receptor-α: regulation by synthesis, modification and degradation , 2002, Cellular and Molecular Life Sciences CMLS.
[17] F. Gannon,et al. Minireview: genomic organization of the human ERalpha gene promoter region. , 2001, Molecular endocrinology.
[18] S. Hilsenbeck,et al. Sp1 is essential for estrogen receptor α gene transcription , 2002, The Journal of Steroid Biochemistry and Molecular Biology.
[19] R. Cardiff,et al. Genetically Engineered Mouse Models of Mammary Intraepithelial Neoplasia , 2000, Journal of Mammary Gland Biology and Neoplasia.
[20] A. Aboussekhra. Role of cancer-associated fibroblasts in breast cancer development and prognosis. , 2011, The International journal of developmental biology.
[21] C. Loddenkemper,et al. WNT10B/β-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer , 2013, EMBO molecular medicine.
[22] Huaixing Li,et al. Murine glypican-4 gene structure and expression; Sp1 and Sp3 play a major role in glypican-4 expression in 3T3-F442A cells. , 2004, Biochimica et biophysica acta.
[23] D. Radisky,et al. Mammary Involution and Breast Cancer Risk: Transgenic Models and Clinical Studies , 2009, Journal of Mammary Gland Biology and Neoplasia.
[24] Eriko Suzuki,et al. Wnt/beta-catenin and estrogen signaling converge in vivo. , 2004, The Journal of biological chemistry.
[25] Shalom Madar,et al. 'Cancer associated fibroblasts'--more than meets the eye. , 2013, Trends in molecular medicine.
[26] Alexander E. Kel,et al. TRANSFAC® and its module TRANSCompel®: transcriptional gene regulation in eukaryotes , 2005, Nucleic Acids Res..
[27] M. Lindstrom,et al. ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[28] H. Stevenson,et al. Molecular and Cellular Determinants of Estrogen Receptor Expression , 2004 .
[29] J. Lee,et al. bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. , 1995, Cancer research.
[30] Ole Winther,et al. JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update , 2007, Nucleic Acids Res..
[31] Lothar Hennighausen,et al. Information networks in the mammary gland , 2005, Nature Reviews Molecular Cell Biology.
[32] H. Varmus,et al. Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[33] S. Fuqua,et al. Regulation of the estrogen receptor alpha minimal promoter by Sp1, USF-1 and ERalpha. , 2004, Breast cancer research and treatment.
[34] Ramon Kranaster,et al. A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro , 2011, Nucleic acids research.
[35] S. Hayashi,et al. Estrogen-related cancer microenvironment of breast carcinoma. , 2009, Endocrine journal.
[36] H. Stevenson,et al. Molecular and cellular determinants of estrogen receptor alpha expression. , 2004, Molecular and cellular biology.
[37] T. Dale,et al. Wnt signalling in murine postnatal mammary gland development , 2012, Acta physiologica.
[38] M. Bienz,et al. Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function , 2004, Nature Cell Biology.
[39] M. Edery,et al. The lack of effect of phenol red or estradiol on the growth response of human, rat, and mouse mammary cells in primary culture. , 1988, Endocrinology.
[40] A. J. Valente,et al. Regulation of the Estrogen Receptor α Minimal Promoter by Sp1, USF-1 and ERα , 2004, Breast Cancer Research and Treatment.
[41] M. Delorenzi,et al. Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. , 2010, Cancer research.
[42] X. Dai,et al. Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice , 2013, Oncogene.
[43] M. Abdelrahim,et al. Sp transcription factor family and its role in cancer. , 2005, European journal of cancer.
[44] F. Gannon,et al. Human estrogen receptor-alpha: regulation by synthesis, modification and degradation. , 2002, Cellular and molecular life sciences : CMLS.
[45] Walter Birchmeier,et al. Balancing cell adhesion and Wnt signaling, the key role of β-catenin , 2006 .
[46] L. Donehower,et al. P53 genotype as a determinant of ER expression and tamoxifen response in the MMTV-Wnt-1 model of mammary carcinogenesis , 2011, Breast Cancer Research and Treatment.
[47] Jie Tian,et al. Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells. , 2009, Cancer research.
[48] Jungsuk An,et al. Epithelial–mesenchymal transition in breast cancer correlates with high histological grade and triple‐negative phenotype , 2012, Histopathology.
[49] Patrick Franken,et al. A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis , 2009, PLoS genetics.
[50] V. Band,et al. Mouse models of estrogen receptor-positive breast cancer , 2011, Journal of carcinogenesis.
[51] H. Varmus,et al. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice , 1988, Cell.
[52] Martin Koš,et al. 0888-8809/01/$03.00/0 Molecular Endocrinology 15(12):2057–2063 Printed in U.S.A. Copyright © 2001 by The Endocrine Society Minireview: Genomic Organization of the Human ER � Gene Promoter Region , 2022 .
[53] F. Brembeck,et al. Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. , 2004, Genes & development.
[54] H. Varmus,et al. A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha. , 1999, Cancer research.
[55] F. Brembeck,et al. BCL9-2 promotes early stages of intestinal tumor progression. , 2011, Gastroenterology.
[56] Barry Komm,et al. Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. , 2003, Endocrinology.
[57] I. Treilleux,et al. A transcriptional enhancer required for the differential expression of the human estrogen receptor in breast cancers , 1997, Molecular and cellular biology.
[58] A. Howell,et al. A putative human breast stem cell population is enriched for steroid receptor-positive cells. , 2005, Developmental biology.
[59] R. Kucherlapati,et al. Genetic Mechanisms in Apc-Mediated Mammary Tumorigenesis , 2009, PLoS genetics.
[60] M. Imamura,et al. Mechanisms of estrogen receptor-α upregulation in breast cancers , 2010, Medical Molecular Morphology.
[61] J. Bergh,et al. Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[62] P. Cowin,et al. Key signaling nodes in mammary gland development and cancer: β-catenin , 2010, Breast Cancer Research.
[63] H. Varmus,et al. A Mouse Mammary Tumor Virus-Wnt-1 Transgene Induces Mammary Gland Hyperplasia and Tumorigenesis in Mice Lacking Estrogen Receptor-α , 1999 .
[64] Y. Kawasaki,et al. Wnt/β-Catenin and Estrogen Signaling Converge in Vivo* , 2004, Journal of Biological Chemistry.
[65] R. Fodde,et al. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. , 2007, Current opinion in cell biology.
[66] Sandipan Chatterjee,et al. Wnt/wingless Signaling Requires Bcl9/legless-mediated Recruitment of Pygopus to the Nuclear Beta-catenin-tcf Complex , 2022 .
[67] Riccardo Fodde,et al. Wnt/β-catenin signaling in cancer stemness and malignant behavior , 2007 .
[68] S. Hilsenbeck,et al. Sp1 is essential for estrogen receptor alpha gene transcription. , 2002, The Journal of steroid biochemistry and molecular biology.
[69] J. Gustafsson,et al. The different roles of ER subtypes in cancer biology and therapy , 2011, Nature Reviews Cancer.