A genetic variant in the gene encoding adrenomedullin predicts the development of dysglycemia over 6.4 years in Chinese.

[1]  M. Savolainen,et al.  Genetic and environmental determinants of total and high-molecular weight adiponectin in families with low HDL-cholesterol and early onset coronary heart disease. , 2010, Atherosclerosis.

[2]  A. Vidal-Puig,et al.  PPARs and adipocyte function , 2010, Molecular and Cellular Endocrinology.

[3]  P. Joyce,et al.  Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetine , 2010, The Pharmacogenomics Journal.

[4]  J. Todd,et al.  Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium , 2009, Diabetes.

[5]  C. Lau,et al.  Association Between Raised Blood Pressure and Dysglycemia in Hong Kong Chinese , 2008, Diabetes Care.

[6]  Bo Zhang,et al.  The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study , 2008, The Lancet.

[7]  C. Lau,et al.  Components of the metabolic syndrome predictive of its development: a 6‐year longitudinal study in Hong Kong Chinese , 2008, Clinical endocrinology.

[8]  B. Cheung,et al.  The role of urotensin II in the metabolic syndrome , 2008, Peptides.

[9]  T. Ravikumar,et al.  Vasoactive Hormone Adrenomedullin and Its Binding Protein: Anti-Inflammatory Effects by Up-Regulating Peroxisome Proliferator-Activated Receptor-γ1 , 2007, The Journal of Immunology.

[10]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[11]  C. Lau,et al.  Development of Diabetes in Chinese With the Metabolic Syndrome , 2007, Diabetes Care.

[12]  Kazuhiro Takahashi,et al.  Adrenomedullin is a novel adipokine: Adrenomedullin in adipocytes and adipose tissues , 2007, Peptides.

[13]  P. Rouet,et al.  Adrenomedullin Inhibits Adipogenesis Under Transcriptional Control of Insulin , 2007, Diabetes.

[14]  K. Nazar,et al.  Effect of prolonged dynamic exercise on plasma adrenomedullin concentration in healthy young men. , 2006, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[15]  B. Cheung,et al.  Adrenomedullin--a potential disease activity marker and suppressor of nephritis activity in systemic lupus erythematosus. , 2006, Rheumatology.

[16]  T. Ishimitsu,et al.  Pathophysiologic and therapeutic implications of adrenomedullin in cardiovascular disorders. , 2006, Pharmacology & therapeutics.

[17]  K. Kitamura,et al.  Plasma adrenomedullin level and development of hypertension , 2006, Journal of Human Hypertension.

[18]  J. Staessen,et al.  Blood pressure and urinary sodium excretion in relation to the A-1984G adrenomedullin polymorphism in a Chinese population. , 2006, Kidney international.

[19]  K. Nakao,et al.  Expression of the adrenomedullin gene in adipose tissue , 2005, Regulatory Peptides.

[20]  B. Cheung,et al.  Differential induction of adrenomedullin, interleukins and tumour necrosis factor‐αby lipopolysaccharide in rat tissues in vivo , 2005, Clinical and experimental pharmacology & physiology.

[21]  T. Nakayama,et al.  Haplotype-Based Case-Control Study Revealing an Association between the Adrenomedullin Gene and Proteinuria in Subjects with Essential Hypertension , 2005, Hypertension Research.

[22]  T. Horbach,et al.  Maturation of the expression of adrenomedullin, endothelin-1 and nitric oxide synthases in adipose tissues from childhood to adulthood , 2005, International Journal of Obesity.

[23]  T. Nakayama,et al.  Association study of calcitonin-receptor-like receptor gene in essential hypertension. , 2005, American journal of hypertension.

[24]  B. Cheung,et al.  Adrenomedullin is both proinflammatory and antiinflammatory: its effects on gene expression and secretion of cytokines and macrophage migration inhibitory factor in NR8383 macrophage cell line. , 2005, Endocrinology.

[25]  Mark Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[26]  T. Asano,et al.  Angiotensin II-induced insulin resistance is enhanced in adrenomedullin-deficient mice. , 2004, Endocrinology.

[27]  B. Cheung,et al.  Adrenomedullin: its role in the cardiovascular system. , 2004, Seminars in vascular medicine.

[28]  T. Ishimitsu,et al.  Microsatellite DNA polymorphism of human adrenomedullin gene in type 2 diabetic patients with renal failure. , 2003, Kidney international.

[29]  T. Asano,et al.  Deficiency of Adrenomedullin Induces Insulin Resistance by Increasing Oxidative Stress , 2003, Hypertension.

[30]  K. Kangawa,et al.  Plasma levels of adrenomedullin and atrial and brain natriuretic peptides in the general population: their relations to age and pulse pressure. , 2002, Hypertension research : official journal of the Japanese Society of Hypertension.

[31]  S. Fowler,et al.  Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. , 2002 .

[32]  T. Ishimitsu,et al.  Chromosomal sublocalization and microsatellite DNA polymorphism of human adrenomedullin gene , 2001, Peptides.

[33]  T. Ishimitsu,et al.  Microsatellite DNA Polymorphism of Human Adrenomedullin Gene in Normotensive Subjects and Patients With Essential Hypertension , 2001, Hypertension.

[34]  T. Valle,et al.  Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. , 2001, The New England journal of medicine.

[35]  A. Sevinç,et al.  Relationship between plasma adrenomedullin levels and metabolic control, risk factors, and diabetic microangiopathy in patients with type 2 diabetes. , 2000, Diabetes care.

[36]  T. Buchanan,et al.  Is adrenomedullin a causal agent in some cases of type 2 diabetes? , 1999, Peptides.

[37]  T. Fujita,et al.  Hyperglycemia increases vascular adrenomedullin expression. , 1999, Biochemical and biophysical research communications.

[38]  P. Zimmet,et al.  Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation , 1998, Diabetic medicine : a journal of the British Diabetic Association.

[39]  T. Fujita,et al.  Plasma adrenomedullin in diabetes , 1997, The Lancet.

[40]  T. Moody,et al.  Regulation of insulin secretion and blood glucose metabolism by adrenomedullin. , 1996, Endocrinology.

[41]  T. Ishimitsu,et al.  Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. , 1994, The Journal of clinical investigation.

[42]  T. Ishimitsu,et al.  Genomic structure of human adrenomedullin gene. , 1994, Biochemical and biophysical research communications.

[43]  K. Kangawa,et al.  Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. , 1993, Biochemical and biophysical research communications.

[44]  Jinkui Yang,et al.  Angiotensin-converting enzyme gene polymorphism is associated with type 2 diabetes: a meta-analysis , 2009, Molecular Biology Reports.

[45]  C. Lau,et al.  Relationship between the metabolic syndrome and the development of hypertension in the Hong Kong Cardiovascular Risk Factor Prevalence Study-2 (CRISPS2). , 2008, American journal of hypertension.

[46]  G. Mingrone Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects. , 2008 .

[47]  T. Ishimitsu,et al.  Effect of a hypocaloric diet on adrenomedullin and natriuretic peptides in obese patients with essential hypertension. , 2000, Journal of cardiovascular pharmacology.

[48]  B. Cheung,et al.  Elevated plasma levels of human adrenomedullin in cardiovascular, respiratory, hepatic and renal disorders. , 1997, Clinical science.