Wide-field time-correlated single photon counting-based fluorescence lifetime imaging microscopy

[1]  M. Melamed Detection , 2021, SETI: Astronomy as a Contact Sport.

[2]  S. Tisa,et al.  SPAD based imaging of Cherenkov light in radiation therapy , 2019, BiOS.

[3]  T Binzoni,et al.  Time domain diffuse Raman spectrometer based on a TCSPC camera for the depth analysis of diffusive media. , 2018, Optics letters.

[4]  Peter Svihra,et al.  Coincidence velocity map imaging using Tpx3Cam, a time stamping optical camera with 1.5 ns timing resolution. , 2017, The Review of scientific instruments.

[5]  Klaus Suhling,et al.  Photon counting phosphorescence lifetime imaging with TimepixCam. , 2017, The Review of scientific instruments.

[6]  W. Becker,et al.  A wide-field TCSPC FLIM system based on an MCP PMT with a delay-line anode. , 2016, The Review of scientific instruments.

[7]  Alix Le Marois,et al.  Picosecond wide-field time-correlated single photon counting fluorescence microscopy with a delay line anode detector , 2016 .

[8]  D. Phillips A lifetime in photochemistry; some ultrafast measurements on singlet states , 2016, Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[9]  Klaus Suhling,et al.  Photon Counting Imaging with an Electron-Bombarded Pixel Image Sensor , 2016, Sensors.

[10]  A. Nomerotski,et al.  TimepixCam: a fast optical imager with time-stamping , 2016 .

[11]  Wolfgang Becker,et al.  Combined fluorescence and phosphorescence lifetime imaging , 2016 .

[12]  Maria Giuseppina Bisogni,et al.  Development of analog solid-state photo-detectors for Positron Emission Tomography , 2016 .

[13]  K. Suhling,et al.  Wide-field TCSPC: methods and applications , 2016 .

[14]  S. Pellegrini,et al.  A SPAD-Based QVGA Image Sensor for Single-Photon Counting and Quanta Imaging , 2016, IEEE Transactions on Electron Devices.

[15]  Nikola Krstajić,et al.  0.5 billion events per second time correlated single photon counting using CMOS SPAD arrays. , 2015, Optics letters.

[16]  N. Sergent,et al.  Photon counting imaging with an electron-bombarded CCD: towards wide-field time-correlated single photon counting (TCSPC) , 2015 .

[17]  K. Suhling,et al.  Wide-field time-correlated single photon counting (TCSPC) microscopy with time resolution below the frame exposure time , 2015 .

[18]  A. Dominjon,et al.  Single photon detection and localization accuracy with an ebCMOS camera , 2015 .

[19]  Alix Le Marois,et al.  Fluorescence lifetime imaging (FLIM): Basic concepts and some recent developments , 2015 .

[20]  Klaus Suhling,et al.  Microsecond wide-field TCSPC microscopy based on an ultra-fast CMOS camera , 2015, Photonics West - Biomedical Optics.

[21]  K. Suhling,et al.  Sub-μs time resolution in wide-field time-correlated single photon counting microscopy obtained from the photon event phosphor decay , 2015 .

[22]  N. Krstajić,et al.  A high speed multifocal multiphoton fluorescence lifetime imaging microscope for live-cell FRET imaging. , 2015, Biomedical optics express.

[23]  R. Hartig,et al.  Position sensitive detector for fluorescence lifetime imaging , 2014 .

[24]  Klaus Suhling,et al.  Photon counting imaging with an electron-bombarded CCD: towards a parallel-processing photoelectronic time-to-amplitude converter. , 2014, The Review of scientific instruments.

[25]  Klaus Suhling,et al.  Time-resolved multifocal multiphoton microscope for high speed FRET imaging in vivo. , 2014, Optics letters.

[26]  K. Suhling,et al.  Wide-field time-correlated single-photon counting (TCSPC) lifetime microscopy with microsecond time resolution. , 2014, Optics letters.

[27]  E. Charbon Single-photon imaging in complementary metal oxide semiconductor processes , 2014, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[28]  John W. Haycock,et al.  Long-lived metal complexes open up microsecond lifetime imaging microscopy under multiphoton excitation: from FLIM to PLIM and beyond , 2014 .

[29]  Claire Vallance,et al.  Fast sensors for time-of-flight imaging applications. , 2014, Physical chemistry chemical physics : PCCP.

[30]  R. Hartig,et al.  Wide-field fluorescence lifetime imaging with multi-anode detectors. , 2014, Methods in molecular biology.

[31]  Frauke Zipp,et al.  Parallelized TCSPC for Dynamic Intravital Fluorescence Lifetime Imaging: Quantifying Neuronal Dysfunction in Neuroinflammation , 2013, PloS one.

[32]  A. Cheng,et al.  Development of new photon-counting detectors for single-molecule fluorescence microscopy , 2013, Philosophical Transactions of the Royal Society B: Biological Sciences.

[33]  R. Heeren,et al.  Detection systems for mass spectrometry imaging: a perspective on novel developments with a focus on active pixel detectors. , 2013, Rapid communications in mass spectrometry : RCM.

[34]  E. Charbon,et al.  SPAD-based Sensors , 2013 .

[35]  John V. Vallerga,et al.  Neutron radiography with sub-15 μm resolution through event centroiding , 2012 .

[36]  Claire Vallance,et al.  PImMS, a fast event-triggered monolithic pixel detector with storage of multiple timestamps , 2012 .

[37]  Alessandro Esposito,et al.  Beyond Range: Innovating Fluorescence Microscopy , 2012, Remote. Sens..

[38]  D. Ray,et al.  Detection, Quantification, and Microlocalisation of Targets of Pesticides Using Microchannel Plate Autoradiographic Imagers , 2011, Molecules.

[39]  I. Young,et al.  Photon budget analysis for fluorescence lifetime imaging microscopy. , 2011, Journal of biomedical optics.

[40]  Christian Götze,et al.  Wide-Field Multi-Parameter FLIM: Long-Term Minimal Invasive Observation of Proteins in Living Cells , 2011, PloS one.

[41]  Klaus Suhling,et al.  Photon arrival timing with sub-camera exposure time resolution in wide-field time-resolved photon counting imaging. , 2010, Optics express.

[42]  N. Sergent,et al.  Rapid wide-field photon counting imaging with microsecond time resolution. , 2010, Optics express.

[43]  J. Crain,et al.  Fluorescence lifetime biosensing with DNA microarrays and a CMOS-SPAD imager , 2010, Biomedical optics express.

[44]  David Stoppa,et al.  A SPAD-based pixel linear array for high-speed time-gated fluorescence lifetime imaging , 2009, 2009 Proceedings of ESSCIRC.

[45]  R. Collins,et al.  Long-range time-of-flight scanning sensor based on high-speed time-correlated single-photon counting. , 2009, Applied optics.

[46]  S. Weiss,et al.  Single-quantum dot imaging with a photon counting camera. , 2009, Current pharmaceutical biotechnology.

[47]  K. Kemnitz,et al.  Wide-field photon counting fluorescence lifetime imaging microscopy: application to photosynthesizing systems , 2009, Photosynthesis Research.

[48]  Jason McPhate,et al.  Detection efficiency, spatial and timing resolution of thermal and cold neutron counting MCP detectors , 2009 .

[49]  J. Milnes,et al.  Image charge multi-role and function detectors , 2009 .

[50]  J. Crain,et al.  Fluorescence Lifetime Imaging of Quantum Dot Labeled DNA Microarrays , 2009, International journal of molecular sciences.

[51]  C. Tregidgo,et al.  Effect of refractive index on the fluorescence lifetime of green fluorescent protein. , 2008, Journal of biomedical optics.

[52]  F. Wouters,et al.  Optimizing frequency-domain fluorescence lifetime sensing for high-throughput applications: photon economy and acquisition speed. , 2007, Journal of the Optical Society of America. A, Optics, image science, and vision.

[53]  J. Bereiter-Hahn,et al.  Spectrally and spatially resolved fluorescence lifetime imaging in living cells: TRPV4-microfilament interactions. , 2007, Archives of biochemistry and biophysics.

[54]  John V. Vallerga,et al.  High spatial resolution neutron sensing microchannel plate detectors , 2007 .

[55]  A. Larkum,et al.  Excitation energy transfer from phycobiliprotein to chlorophyll d in intact cells of Acaryochloris marina studied by time- and wavelength-resolved fluorescence spectroscopy , 2005, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[56]  Valentina Emiliani,et al.  Low-intensity two-dimensional imaging of fluorescence lifetimes in living cells , 2003 .

[57]  E. Gratton,et al.  Fluorescence lifetime imaging for the two-photon microscope: time-domain and frequency-domain methods. , 2003, Journal of biomedical optics.

[58]  K. Carlsson,et al.  Theoretical investigation of the signal-to-noise ratio in fluorescence lifetime imaging. , 2003, Journal of the Optical Society of America. A, Optics, image science, and vision.

[59]  H. Offerhaus,et al.  Application of a time-resolved event counting technique in velocity map imaging , 2002 .

[60]  Liam B. C. Worth,et al.  Position sensitive anodes for MCP read-out using induced charge measurement , 2002 .

[61]  Ottmar Jagutzki,et al.  Multiple hit read-out of a microchannel plate detector with a three-layer delay-line anode , 2001, 2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310).

[62]  J. Nicolas,et al.  Homo-FRET microscopy in living cells to measure monomer-dimer transition of GFP-tagged proteins. , 2001, Biophysical journal.

[63]  D. Strasser,et al.  An innovative approach to multiparticle three-dimensional imaging , 2000, 2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149).

[64]  D. Delpy,et al.  A 32-channel time-resolved instrument for medical optical tomography , 2000 .

[65]  M. Yaffe,et al.  The effect of phosphor persistence on image quality in digital x-ray scanning systems. , 1998, Medical physics.

[66]  Grigory I. Vishnevsky,et al.  The Megapixel EBCCD: A high-resolution imaging tube sensitive to single photons 1 1 This work is part of the CERN Research and Development programme RD46. , 1998 .

[67]  K. Kemnitz,et al.  Detector for multichannel spectroscopy and fluorescence lifetime imaging on the picosecond timescale , 1997 .

[68]  D. Birch,et al.  MULTIPLEXED SINGLE-PHOTON COUNTING. II. THE STATISTICAL THEORY OF TIME-CORRELATED MEASUREMENTS , 1996 .

[69]  David J. S. Birch,et al.  Multiplexed single-photon counting. I. A time-correlated fluorescence lifetime camera , 1996 .

[70]  N. Pailer,et al.  Faint object camera: European contribution to the Hubble Space Telescope☆ , 1992 .

[71]  James F. Pearson,et al.  The direct detection of thermal neutrons by imaging microchannel-plate detectors , 1990 .

[72]  D. O'connor,et al.  Time-Correlated Single Photon Counting , 1984 .

[73]  A. Boksenberg Advances in detectors for astronomical spectroscopy , 1982, Philosophical Transactions of the Royal Society of London. Series A, Mathematical and Physical Sciences.

[74]  David J. S. Birch,et al.  Coaxial nanosecond flashlamp , 1981 .

[75]  Colin Lewis,et al.  The Measurement of Short‐Lived Fluorescence Decay Using the Single Photon Counting Method , 1973 .

[76]  T. Binkert,et al.  The measurement of fluorescence decay curves with the single-photon counting method and the evaluation of rate parameters , 1972 .

[77]  R. Bachrach A Photon Counting Apparatus for Kinetic and Spectral Measurements , 1972 .

[78]  G. E. Thomas,et al.  Measurement of the Time Dependence of Scintillation Intensity by a Delayed‐Coincidence Method , 1961 .

[79]  H. E. Petch,et al.  DESIGN AND USE OF A COINCIDENCE CIRCUIT OF SHORT RESOLVING TIME , 1952 .

[80]  B. Rossi Method of Registering Multiple Simultaneous Impulses of Several Geiger's Counters. , 1930, Nature.

[81]  W. Bothe,et al.  Das Wesen der Höhenstrahlung , 1929 .