Components of biological variation, including seasonality, in blood concentrations of TSH, TT3, FT4, PRL, cortisol and testosterone in healthy volunteers

OBJECTIVEThere are few detailed studies of annual or seasonal variations in hormone concentrations in man. This study examines the components of biological variation, including seasonality, in plasma TSH, total T3 (TT3), free T4 (FT4), PRL, cortisol and testosterone in healthy volunteers.

[1]  N. Konno,et al.  Seasonal variation of serum thyrotropin concentration and thyrotropin response to thyrotropin-releasing hormone in patients with primary hypothyroidism on constant replacement dosage of thyroxine. , 1982, The Journal of clinical endocrinology and metabolism.

[2]  Harris Ek.  Statistical aspects of reference values in clinical pathology. , 1981 .

[3]  U. Feldt-Rasmussen,et al.  Long-term variability in serum thyroglobulin and thyroid related hormones in healthy subjects. , 1980, Acta endocrinologica.

[4]  H. Neels,et al.  Components of biological variation in prolyl endopeptidase and dipeptidyl-peptidase IV activity in plasma of healthy subjects. , 1994, Clinical chemistry.

[5]  P. Brombacher,et al.  Short-term and long-term intra-individual variations and critical differences of clinical chemical laboratory parameters. , 1985, Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie.

[6]  C. Blomquist,et al.  Chronobiology of the Hypothalamic-Pituitary-Gonadal Axis in Men and Women , 1992 .

[7]  A. Smals,et al.  Seasonal variation in serum T3 and T4 levels in man. , 1977, The Journal of clinical endocrinology and metabolism.

[8]  P. Willems,et al.  A radioimmunoassay study and comparison of seasonal variation in plasma triiodothyronine and thyroxine concentrations in normal healthy persons , 1974 .

[9]  H. Meltzer,et al.  Seasonal variation and meteotropism in various self-rated psychological and physiological features of a normal couple , 1992, International journal of biometeorology.

[10]  E. Haus,et al.  Chronobiology of the Hypothalamic-Pituitary-Thyroid Axis , 1992 .

[11]  Charles W. Ostrom.  Time Series Analysis: Regression Techniques , 1978 .

[12]  R. Frairia,et al.  Circannual rhythmicities of cortisol levels in the peripheral plasma of healthy subjects. , 1982, Chronobiologia.

[13]  M. Simoni,et al.  Circannual rhythm of plasma thyrotropin in middle-aged and old euthyroid subjects. , 1990, Hormone research.

[14]  C. Fraser.  Data on biological variation: essential prerequisites for introducing new procedures? , 1994, Clinical chemistry.

[15]  F. Halberg.  Quo vadis basic and clinical chronobiology: promise for health maintenance. , 1983, The American journal of anatomy.

[16]  E. Haus,et al.  Chronobiology in laboratory medicine. , 1993, Annali dell'Istituto superiore di sanita.

[17]  G. Pennington.  Interpretation of clinical chemistry laboratory data , 1987 .

[18]  A. Angeli,et al.  Chronobiology of the Hypothalamic-Pituitary-Adrenal and Renin-Angiotensin-Aldosterone Systems , 1992 .

[19]  L. Sackett,et al.  Chronobiological studies of plasma prolactin in women in Kyushu, Japan, and Minnesota, USA. , 1980, The Journal of clinical endocrinology and metabolism.

[20]  P. Vogelaere,et al.  Spectral resolution of cardio-circulatory variations in men measured by autorhythmometry over 2 years , 1990, International journal of biometeorology.

[21]  C. Ricós,et al.  Quality Goals for Hormone Testing , 1990, Annals of clinical biochemistry.

[22]  F Halberg,et al.  Inferential statistical methods for estimating and comparing cosinor parameters. , 1982, Chronobiologia.

[23]  D. Peeters,et al.  Synchronized annual rhythms in violent suicide rate, ambient temperature and the light‐dark span , 1994, Acta psychiatrica Scandinavica.

[24]  C. Fraser,et al.  Intra- and interindividual biological variation of five analytes used in assessing thyroid function: implications for necessary standards of performance and the interpretation of results. , 1986, Clinical chemistry.

[25]  K. Ashwell,et al.  Circannual and Within-Individual Variation of Thyroid Function Tests in Normal Subjects , 1985, Annals of clinical biochemistry.

[26]  A. Reinberg,et al.  Annual Endocrine Rhythms in Healthy Young Adult Men: Their Implication in Human Biology and Medicine , 1978 .

[27]  C G Fraser,et al.  Generation and application of data on biological variation in clinical chemistry. , 1989, Critical reviews in clinical laboratory sciences.

[28]  A. Bellastella,et al.  CIRCANNUAL RHYTHMS OF PLASMA GROWTH HORMONE, THYROTROPIN AND THYROID HORMONES IN PREPUBERTY , 1984, Clinical endocrinology.

[29]  E. Haus,et al.  Reference values for chronopharmacology , 1988 .