Noncontact Charge Shielding Knife for Liquid Microfluidics.

Multibehavioral droplet manipulation in a precise and programmed manner is crucial for stoichiometry, biological virus detection, and intelligent lab-on-a-chip. Apart from fundamental navigation, merging, splitting, and dispensing of the droplets are required for being combined in a microfluidic chip as well. Yet, existing active manipulations including strategies from light to magnetism are arduous to use to split liquids on superwetting surfaces without mass loss and contamination, because of the high cohesion and Coanda effect. Here, we demonstrate a charge shielding mechanism (CSM) for platforms to integrate with a series of functions. In response to attachment of shielding layers from the bottom, the instantaneous and repeatable change of local potential on our platform achieves the desired loss-free manipulation of droplets, with a wide-ranging surface tension from 25.7 mN m-1 to 87.6 mN m-1, functioning as a noncontact air knife to cleave, guide, rotate, and collect reactive monomers on demand. With further refinement of the surface circuit, the droplets, just as the electron, can be programmed to be transported directionally at extremely high speeds of 100 mm s-1. This new generation of microfluidics is expected to be applied in the field of bioanalysis, chemical synthesis, and diagnostic kit.

[1]  Yuxin Song,et al.  Triboelectric wetting for continuous droplet transport , 2022, Science advances.

[2]  Fang Wang,et al.  Light-induced charged slippery surfaces , 2022, Science advances.

[3]  D. Belder,et al.  On-the-Fly Mass Spectrometry in Digital Microfluidics Enabled by a Microspray Hole: Toward Multidimensional Reaction Monitoring in Automated Synthesis Platforms. , 2022, Journal of the American Chemical Society.

[4]  Z. Dong,et al.  Overflow Control for Sustainable Development by Superwetting Surface with Biomimetic Structure. , 2022, Chemical reviews.

[5]  D. Juncker,et al.  Microfluidic chain reaction of structurally programmed capillary flow events , 2022, Nature.

[6]  Huan Liu,et al.  Electrochemical On‐Site Switching of the Directional Liquid Transport on a Conical Fiber , 2022, Advanced materials.

[7]  Zuankai Wang,et al.  Electrostatic tweezer for droplet manipulation , 2022, Proceedings of the National Academy of Sciences.

[8]  Wulin Zhu,et al.  A Biocompatible Vibration‐Actuated Omni‐Droplets Rectifier with Large Volume Range Fabricated by Femtosecond Laser , 2021, Advanced materials.

[9]  F. Mugele,et al.  Wetting ridge assisted programmed magnetic actuation of droplets on ferrofluid-infused surface , 2021, Nature Communications.

[10]  B. Grzybowski,et al.  An Electrocatalytic Reaction As a Basis for Chemical Computing in Water Droplets. , 2021, Journal of the American Chemical Society.

[11]  Yahua Liu,et al.  Three-dimensional capillary ratchet-induced liquid directional steering , 2021, Science.

[12]  Zhong Lin Wang,et al.  Quantifying Contact‐Electrification Induced Charge Transfer on a Liquid Droplet after Contacting with a Liquid or Solid , 2021, Advanced materials.

[13]  Liqiu Wang,et al.  Furcated droplet motility on crystalline surfaces , 2021, Nature Nanotechnology.

[14]  P. Arosio,et al.  Programmable Zwitterionic Droplets as Biomolecular Sorters and Model of Membraneless Organelles , 2021, Advances in Materials.

[15]  Shutao Wang,et al.  A Wetting‐Enabled‐Transfer (WET) Strategy for Precise Surface Patterning of Organohydrogels , 2021, Advanced materials.

[16]  A. Schug,et al.  Assembly of Multi‐Spheroid Cellular Architectures by Programmable Droplet Merging , 2020, Advanced materials.

[17]  Wei Li,et al.  Design of multi-scale textured surfaces for unconventional liquid harnessing , 2020 .

[18]  Liqiu Wang,et al.  Photopyroelectric microfluidics , 2020, Science Advances.

[19]  Lei Jiang,et al.  Directional liquid dynamics of interfaces with superwettability , 2020, Science Advances.

[20]  Guofu Zhou,et al.  Charge Trapping‐Based Electricity Generator (CTEG): An Ultrarobust and High Efficiency Nanogenerator for Energy Harvesting from Water Droplets , 2020, Advanced materials.

[21]  Robin H. A. Ras,et al.  Design of robust superhydrophobic surfaces , 2020, Nature.

[22]  Yanlin Song,et al.  Droplet precise self-splitting on patterned-adhesive surfaces for simultaneous multi-detection. , 2020, Angewandte Chemie.

[23]  Lei Jiang,et al.  Ultrafast self-propelled directional liquid transport on the pyramid structured fibers with concave curved surfaces. , 2020, Journal of the American Chemical Society.

[24]  Zheng Li,et al.  Programmable droplet manipulation by a magnetic-actuated robot , 2020, Science Advances.

[25]  Zhong Lin Wang,et al.  A droplet-based electricity generator with high instantaneous power density , 2020, Nature.

[26]  Robbyn K. Anand,et al.  Concentration enrichment, separation, and cation exchange in nanoliter-scale water-in-oil droplets. , 2020, Journal of the American Chemical Society.

[27]  E. Spruijt,et al.  Multiphase Complex Coacervate Droplets , 2019, Journal of the American Chemical Society.

[28]  Noel S Ha,et al.  Ionic-surfactant-mediated electro-dewetting for digital microfluidics , 2019, Nature.

[29]  Xu Deng,et al.  Surface charge printing for programmed droplet transport , 2019, Nature Materials.

[30]  D. Daniel,et al.  Directional pumping of water and oil microdroplets on slippery surface , 2019, Proceedings of the National Academy of Sciences.

[31]  Liqiu Wang,et al.  Loss-Free Photo-Manipulation of Droplets by Pyroelectro-Trapping on Superhydrophobic Surfaces. , 2018, ACS nano.

[32]  M. Raschke,et al.  Mechanism of Electric Power Generation from Ionic Droplet Motion on Polymer Supported Graphene. , 2018, Journal of the American Chemical Society.

[33]  Meicheng Li,et al.  Self-Powered Microfluidic Transport System Based on Triboelectric Nanogenerator and Electrowetting Technique. , 2018, ACS nano.

[34]  B. Grzybowski,et al.  Systems of mechanized and reactive droplets powered by multi-responsive surfactants , 2018, Nature.

[35]  Jun-ichi Yoshida,et al.  Submillisecond organic synthesis: Outpacing Fries rearrangement through microfluidic rapid mixing , 2016, Science.

[36]  Deyuan Zhang,et al.  Continuous directional water transport on the peristome surface of Nepenthes alata , 2016, Nature.

[37]  J. Robinson,et al.  Chemical gradients on graphene to drive droplet motion. , 2013, ACS nano.

[38]  Baoping Wang,et al.  Bioinspired multifunctional Janus particles for droplet manipulation. , 2013, Journal of the American Chemical Society.

[39]  J. Viovy,et al.  Programmable magnetic tweezers and droplet microfluidic device for high-throughput nanoliter multi-step assays. , 2012, Angewandte Chemie.

[40]  Jin Zhai,et al.  Directional water collection on wetted spider silk , 2010, Nature.

[41]  Helen Song,et al.  Reactions in droplets in microfluidic channels. , 2006, Angewandte Chemie.

[42]  Luke P. Lee,et al.  Optofluidic control using photothermal nanoparticles , 2006, Nature materials.

[43]  Xuefeng Gao,et al.  Biophysics: Water-repellent legs of water striders , 2004, Nature.