Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice
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[1] M. Mann,et al. IκB Kinase (IKK)-Associated Protein 1, a Common Component of the Heterogeneous IKK Complex , 1999, Molecular and Cellular Biology.
[2] A. Lin,et al. Coordinate Regulation of IκB Kinases by Mitogen-Activated Protein Kinase Kinase Kinase 1 and NF-κB-Inducing Kinase , 1998, Molecular and Cellular Biology.
[3] G. W. Peet,et al. Recombinant IκB Kinases α and β Are Direct Kinases of IκBα* , 1998, The Journal of Biological Chemistry.
[4] M. Hu,et al. IκB kinase-α and -β genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes , 1998 .
[5] E. Zandi,et al. IKK-γ is an essential regulatory subunit of the IκB kinase complex , 1998, Nature.
[6] C. Y. Wang,et al. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. , 1998, Science.
[7] Ebrahim Zandi,et al. Direct Phosphorylation of IκB by IKKα and IKKβ: Discrimination Between Free and NF-κB-Bound Substrate , 1998 .
[8] T. Maniatis,et al. MEKK1 activates both IκB kinase α and IκB kinase β , 1998 .
[9] Christian Stehlik,et al. Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis , 1998, The Journal of experimental medicine.
[10] G. Courtois,et al. Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation , 1998, Cell.
[11] Zhaodan Cao,et al. NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176 , 1998 .
[12] D. Goeddel,et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. , 1998, Science.
[13] Stefan Grimm,et al. The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal , 1998 .
[14] C. Snapper,et al. Nuclear Factor (NF)-κB2 (p100/p52) Is Required for Normal Splenic Microarchitecture and B Cell–mediated Immune Responses , 1998, The Journal of experimental medicine.
[15] Matthias Mann,et al. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation , 1997 .
[16] Mike Rothe,et al. IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK , 1997 .
[17] E. Zandi,et al. The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation , 1997, Cell.
[18] M. Malim,et al. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[19] D. Goeddel,et al. Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[20] David M. Rothwarf,et al. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB , 1997, Nature.
[21] D. Goeddel,et al. Identification and Characterization of an IκB Kinase , 1997, Cell.
[22] P. Barnes,et al. Nuclear factor-κB , 1997 .
[23] M. Karin,et al. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. , 1997, The New England journal of medicine.
[24] S. Nagata,et al. Lethal effect of recombinant human Fas ligand in mice pretreated with Propionibacterium acnes. , 1997, Journal of immunology.
[25] D. Wallach,et al. MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1 , 1997, Nature.
[26] T. Maniatis,et al. Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway , 1997, Cell.
[27] D. Goeddel,et al. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[28] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[29] David Baltimore,et al. An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death , 1996, Science.
[30] Seamus J. Martin,et al. Suppression of TNF-α-Induced Apoptosis by NF-κB , 1996, Science.
[31] Michael Karin,et al. Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death , 1996, Cell.
[32] David Baltimore,et al. NF-κB: Ten Years After , 1996, Cell.
[33] K. Kalli,et al. Interleukin-1 signal transduction. , 1996, Life sciences.
[34] D. Goeddel,et al. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. , 1996, Immunity.
[35] C. Dinarello,et al. Biologic basis for interleukin-1 in disease. , 1996, Blood.
[36] Hong-Bing Shu,et al. TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways , 1996, Cell.
[37] Mike Rothe,et al. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins , 1995, Cell.
[38] E M Schwarz,et al. Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. , 1995, Genes & development.
[39] A. Strasser,et al. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. , 1995, Genes & development.
[40] David Baltimore,et al. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB , 1995, Nature.
[41] D. Goeddel,et al. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation , 1995, Cell.
[42] T. Maniatis,et al. NF-κB: A lesson in family values , 1995, Cell.
[43] David Baltimore,et al. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses , 1995, Cell.
[44] F. Weih,et al. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family , 1995, Cell.
[45] V. Baichwal,et al. Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression , 1994, Molecular and cellular biology.
[46] P. Baeuerle,et al. Function and activation of NF-kappa B in the immune system. , 1994, Annual review of immunology.
[47] P. Swiatek,et al. Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. , 1993, Genes & development.
[48] A. Joyner,et al. Production of targeted embryonic stem cell clones. , 1993 .
[49] S. Akira,et al. IL‐6 and NF‐IL6 in Acute‐Phase Response and Viral Infection , 1992, Immunological reviews.