A new nonparametric statistical approach to detect lumen and Media-Adventitia borders in intravascular ultrasound frames

Intravascular ultrasound (IVUS) imaging is widely known as a powerful interventional imaging modality for diagnosing atherosclerosis, and for treatment planning. In this regard, the detection of lumen and media-adventitia (MA) borders is considered to be a vital process. However, the manual detection of these two borders by the physician is cumbersome due to the large number of frames in a sequence. In addition, no approved universal automatic method has been presented so far due to the great diversity in the appearance of the coronary artery in the images acquired by different IVUS systems. To this end, the present study aimed to provide a new border search theory on the radial profile, based upon the nonparametric statistical approach, and to develop a generic and fully automatic three-step process for extracting the lumen and MA borders in IVUS frames based on the proposed theory. Thereafter, the proposed theory and three-step process were evaluated on synthetic images, as well as on a test set of standard publicly available images, respectively. The results showed that our three-step process could segment the borders with ≥0.82 and with ≥0.75 Jaccard measure (JM) to manual borders in IVUS frames acquired by the 20 MHz and 40 MHz probes, respectively. Based on the results, the lumen and MA borders can be extracted automatically, and the border extraction process can be implemented in parallel for a polar image due to the capability of the present proposed method to estimate the borders for each angle independently.

[1]  Giulio Guagliumi,et al.  La carrera para alcanzar el «patrón oro» en imagen coronaria , 2009 .

[2]  Simon S. Young,et al.  Computerized Data Acquisition and Analysis for the Life Sciences: A Hands-on Guide , 2001 .

[3]  Yong Cheng,et al.  A novel statistical image thresholding method , 2010 .

[4]  N Bom,et al.  An ultrasonic intracardiac scanner. , 1972, Ultrasonics.

[5]  J. Ornato,et al.  ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update 2001 Guidelines for Percutaneous Coronary Intervention). , 2006, Circulation.

[6]  Petia Radeva,et al.  HoliMAb: A holistic approach for Media-Adventitia border detection in intravascular ultrasound , 2012, Medical Image Anal..

[7]  N. Otsu A threshold selection method from gray level histograms , 1979 .

[8]  Meisen Pan,et al.  Two-dimensional extension of variance-based thresholding for image segmentation , 2013, Multidimens. Syst. Signal Process..

[9]  Misael Rosales,et al.  A Basic Model for IVUS Image Simulation , 2005 .

[10]  Qingmao Hu,et al.  On minimum variance thresholding , 2006, Pattern Recognit. Lett..

[11]  João Manuel R. S. Tavares,et al.  Automatic segmentation of the lumen region in intravascular images of the coronary artery , 2017, Medical Image Anal..

[12]  Hui-Fuang Ng Automatic thresholding for defect detection , 2006, Pattern Recognit. Lett..

[13]  Joseph P Ornato,et al.  ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention). , 2006, Journal of the American College of Cardiology.

[14]  Zhao Feng,et al.  Two-Dimensional Otsu's Curve Thresholding Segmentation Method for Gray-Level Images , 2007 .

[15]  Hassan Dao,et al.  Segmentation and detection of media adventitia coronary artery boundary in medical imaging intravascular ultrasound using otsu thresholding , 2015, 2015 International Conference on BioSignal Analysis, Processing and Systems (ICBAPS).

[16]  T. Loupas,et al.  An adaptive weighted median filter for speckle suppression in medical ultrasonic images , 1989 .

[17]  E. Gerardo Mendizabal-Ruiz,et al.  Segmentation of the luminal border in intravascular ultrasound B-mode images using a probabilistic approach , 2013, Medical Image Anal..

[18]  Sang Uk Lee,et al.  A comparative performance study of several global thresholding techniques for segmentation , 1990, Comput. Vis. Graph. Image Process..

[19]  Seyed Kamaledin Setarehdan,et al.  Automatic media-adventitia IVUS image segmentation based on sparse representation framework and dynamic directional active contour model , 2017, Comput. Biol. Medicine.

[20]  Helmut Alt,et al.  Computing the Fréchet distance between two polygonal curves , 1995, Int. J. Comput. Geom. Appl..

[21]  José Ignacio Orlando,et al.  Assessment of image features for vessel wall segmentation in intravascular ultrasound images , 2016, International Journal of Computer Assisted Radiology and Surgery.

[22]  C. Tracy,et al.  American College of Cardiology Clinical Expert Consensus Document on Standards for Acquisition, Measurement and Reporting of Intravascular Ultrasound Studies (IVUS). A report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. , 2001, Journal of the American College of Cardiology.

[23]  Musa H. Asyali,et al.  Image Processing with MATLAB: Applications in Medicine and Biology , 2008 .

[24]  Xianghua Xie,et al.  Automatic segmentation of cross-sectional coronary arterial images , 2017, Comput. Vis. Image Underst..

[25]  E. Gerardo Mendizabal-Ruiz,et al.  Computerized Medical Imaging and Graphics , 2022 .

[26]  J. Alison Noble,et al.  Ultrasound image segmentation: a survey , 2006, IEEE Transactions on Medical Imaging.

[27]  Tong Fang,et al.  Shape-Driven Segmentation of the Arterial Wall in Intravascular Ultrasound Images , 2008, IEEE Transactions on Information Technology in Biomedicine.

[28]  Milan Sonka,et al.  Automated detection of wall and plaque borders in intravascular ultrasound images , 1994, Medical Imaging.

[29]  E. Lehmann Elements of large-sample theory , 1998 .

[30]  Zhenghui Hu,et al.  An artificial neural network method for lumen and media-adventitia border detection in IVUS , 2017, Comput. Medical Imaging Graph..

[31]  Michael G. Strintzis,et al.  A novel active contour model for fully automated segmentation of intravascular ultrasound images: In vivo validation in human coronary arteries , 2007, Comput. Biol. Medicine.

[32]  Joseph P Ornato,et al.  ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to update the 2001 Guidelines for Percutaneous Coronary Intervention , 2006, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[33]  Q. Peng,et al.  An improved Otsu method using the weighted object variance for defect detection , 2015 .

[34]  Nassir Navab,et al.  A State-of-the-Art Review on Segmentation Algorithms in Intravascular Ultrasound (IVUS) Images , 2012, IEEE Transactions on Information Technology in Biomedicine.

[35]  C. Daniel One-at-a-Time Plans , 1973 .

[36]  Carl de Boor,et al.  A Practical Guide to Splines , 1978, Applied Mathematical Sciences.

[37]  Petia Radeva,et al.  Statistical strategy for anisotropic adventitia modelling in IVUS , 2006, IEEE Transactions on Medical Imaging.

[38]  Guy Cloutier,et al.  Segmentation method of intravascular ultrasound images of human coronary arteries , 2014, Comput. Medical Imaging Graph..

[39]  D. M. Titterington,et al.  t -Tests, F -Tests and Otsu's Methods for Image Thresholding , 2011, IEEE Trans. Image Process..

[40]  Anup Basu,et al.  Segmentation of arterial walls in intravascular ultrasound cross‐sectional images using extremal region selection , 2018, Ultrasonics.