Unruptured cerebral aneurysms with the segmental duplicated middle cerebral artery formed a fenestrated structure at origin

Background: Middle cerebral artery (MCA) has a significantly lower incidence of anatomical variations than other intracranial arteries. We present an extremely rare case of unruptured aneurysms with the segmental duplicated MCA (d-MCA) formed a fenestrated structure at origin. Case Description: A 55-year-old female underwent direct surgery for the unruptured aneurysms at the top of the right internal cerebral artery with d-MCA. The d-MCA branches separated at the right internal cerebral artery top and had comparable with that of the main MCA trunk. Moreover, there was an anastomosis between the d-MCA branches. We diagnosed this anastomosis as segmental d-MCA. Two aneurysmal domes were identified during surgery at the origin of the d-MCA, which the main dome protruding backward was wide necked and another small one was collapsed or thrombosed protruding forward. We used a fenestrated clip for the posterior projecting dome, and the aneurysms were successfully obliterated. Conclusion: Although cerebral aneurysms associated with d-MCA are rare, there are technical difficulties in the surgical management. A fenestrated clip might be most reasonable to obtain patency of the parent arteries for the posterior projecting aneurysms if the perforators can be avoided.

[1]  Kan Xu,et al.  The Clinical Characteristics and Treatment Considerations for Intracranial Aneurysms Associated With Middle Cerebral Artery Anomalies: A Systematic Review , 2020, Frontiers in Neurology.

[2]  A. Kostic,et al.  Correlation between multiple cerebral aneurysms and a rare type of segmental duplication of the middle cerebral artery , 2020, BMC Neurology.

[3]  N. Uchiyama Anomalies of the Middle Cerebral Artery , 2017, Neurologia medico-chirurgica.

[4]  J. Hernesniemi,et al.  Management of aneurysms at the origin of duplicated middle cerebral artery: series of four patients with review of the literature. , 2013, World neurosurgery.

[5]  C. McKinstry,et al.  Carotid “Trifurcation” aneurysm: Surgical anatomy and management , 2007, Clinical Neurology and Neurosurgery.

[6]  J. Kuratsu,et al.  Treatment of unruptured duplicated middle cerebral artery aneurysm: case report. , 2006, Surgical Neurology.

[7]  H. Nakajima,et al.  Middle cerebral artery variations: duplicated and accessory arteries. , 1998, AJNR. American journal of neuroradiology.

[8]  J. Teal,et al.  Anomalies of the middle cerebral artery: accessory artery, duplication, and early bifurcation. , 1973, The American journal of roentgenology, radium therapy, and nuclear medicine.

[9]  M. Crompton The pathology of ruptured middle-cerebral aneurysms with special reference to the differences between the sexes. , 1962, Lancet.

[10]  D. H. Padget,et al.  The development of the cranial arteries in the human embryo. , 1948 .