Integrating Multi-omics Data to Dissect Mechanisms of DNA repair Dysregulation in Breast Cancer
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[1] Sriganesh Srihari,et al. Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer , 2016, Molecular oncology.
[2] Jean-Philippe Vert,et al. Changes in correlation between promoter methylation and gene expression in cancer , 2015, BMC Genomics.
[3] Jun S. Liu,et al. Inference of transcriptional regulation in cancers , 2015, Proceedings of the National Academy of Sciences.
[4] Sarah Watson,et al. Pragmatic issues in biomarker evaluation for targeted therapies in cancer , 2015, Nature Reviews Clinical Oncology.
[5] I. Ellis,et al. DNA damage response markers are differentially expressed in BRCA-mutated breast cancers , 2015, Breast Cancer Research and Treatment.
[6] M. Ritchie,et al. Methods of integrating data to uncover genotype–phenotype interactions , 2015, Nature Reviews Genetics.
[7] Yu Shyr,et al. Transcriptome-wide signatures of tumor stage in kidney renal clear cell carcinoma: connecting copy number variation, methylation and transcription factor activity , 2014, Genome Medicine.
[8] E. Lam,et al. FOXM1: An emerging master regulator of DNA damage response and genotoxic agent resistance , 2014, Biochimica et biophysica acta.
[9] Qi Liu,et al. Transcriptome-wide signatures of tumor stage in kidney renal clear cell carcinoma: connecting copy number variation, methylation and transcription factor activity , 2014, Genome Medicine.
[10] Zhaolei Zhang,et al. Regression Analysis of Combined Gene Expression Regulation in Acute Myeloid Leukemia , 2014, PLoS Comput. Biol..
[11] G. Chenevix-Trench,et al. A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy , 2014, Nucleic acids research.
[12] A. Frigessi,et al. Principles and methods of integrative genomic analyses in cancer , 2014, Nature Reviews Cancer.
[13] Ralph R. Weichselbaum,et al. DNA Repair Pathway Gene Expression Score Correlates with Repair Proficiency and Tumor Sensitivity to Chemotherapy , 2014, Science Translational Medicine.
[14] A. Nag,et al. CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases , 2014, Open Biology.
[15] M. Okoniewski,et al. A comprehensive look at transcription factor gene expression changes in colorectal adenomas , 2014, BMC Cancer.
[16] H. Iwase,et al. Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival , 2013, BMC Cancer.
[17] Eleni G. Christodoulou,et al. Assessing Computational Methods for Transcription Factor Target Gene Identification Based on ChIP-seq Data , 2013, PLoS Comput. Biol..
[18] M. Ruíz-Borrego,et al. Prognostic value of CtIP/RBBP8 expression in breast cancer , 2013, Cancer medicine.
[19] Lajos Pusztai,et al. DNA repair gene patterns as prognostic and predictive factors in molecular breast cancer subtypes. , 2013, The oncologist.
[20] Byoung-Tak Zhang,et al. Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer , 2013, Nucleic acids research.
[21] J. Benítez,et al. Analysis of DNA Repair–Related Genes in Breast Cancer Reveals CUL4A Ubiquitin Ligase as a Novel Biomarker of Trabectedin Response , 2013, Molecular Cancer Therapeutics.
[22] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumours , 2013 .
[23] Yong Lin,et al. FOXM1 expression correlates with tumor invasion and a poor prognosis of colorectal cancer. , 2012, Acta histochemica.
[24] Nicola J. Curtin,et al. DNA repair dysregulation from cancer driver to therapeutic target , 2012, Nature Reviews Cancer.
[25] B. Maher. ENCODE: The human encyclopaedia , 2012, Nature.
[26] Manu Setty,et al. Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma , 2012, Molecular systems biology.
[27] Peter Bouwman,et al. The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance , 2012, Nature Reviews Cancer.
[28] Ronald A. Li,et al. The B-MYB Transcriptional Network Guides Cell Cycle Progression and Fate Decisions to Sustain Self-Renewal and the Identity of Pluripotent Stem Cells , 2012, PloS one.
[29] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumors , 2012, Nature.
[30] ENCODEConsortium,et al. An Integrated Encyclopedia of DNA Elements in the Human Genome , 2012, Nature.
[31] A. D’Andrea,et al. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. , 2012, Genes & development.
[32] F. Markowetz,et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups , 2012, Nature.
[33] A. D’Andrea,et al. A DNA Repair Pathway–Focused Score for Prediction of Outcomes in Ovarian Cancer Treated With Platinum-Based Chemotherapy , 2012, Journal of the National Cancer Institute.
[34] David G Johnson,et al. Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage. , 2012, Cancer research.
[35] Jie Zhou,et al. Discovering transcription factor regulatory targets using gene expression and binding data , 2012, Bioinform..
[36] Melissa J. Davis,et al. Gene regulatory network inference: evaluation and application to ovarian cancer allows the prioritization of drug targets , 2012, Genome Medicine.
[37] W. El-Rifai,et al. p73 protein regulates DNA damage repair , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[38] U. Schüller,et al. Expression of FoxM1 Is Required for the Proliferation of Medulloblastoma Cells and Indicates Worse Survival of Patients , 2011, Clinical Cancer Research.
[39] M. Toulmonde,et al. A review of PARP inhibitors: from bench to bedside. , 2011, Annals of oncology : official journal of the European Society for Medical Oncology.
[40] M. Hedayati,et al. Downregulation of Homologous Recombination DNA Repair Genes by HDAC Inhibition in Prostate Cancer Is Mediated through the E2F1 Transcription Factor , 2010, PloS one.
[41] Stefano Piccolo,et al. MicroRNA control of signal transduction , 2010, Nature Reviews Molecular Cell Biology.
[42] Trevor Hastie,et al. Regularization Paths for Generalized Linear Models via Coordinate Descent. , 2010, Journal of statistical software.
[43] M. Teh,et al. Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes , 2010, Molecular Cancer.
[44] Mikael Bodén,et al. MEME Suite: tools for motif discovery and searching , 2009, Nucleic Acids Res..
[45] Juan M. Vaquerizas,et al. A census of human transcription factors: function, expression and evolution , 2009, Nature Reviews Genetics.
[46] A. Godwin,et al. Promoter hypermethylation of the PALB2 susceptibility gene in inherited and sporadic breast and ovarian cancer. , 2008, Cancer research.
[47] Arndt Hartmann,et al. Tight correlation between expression of the Forkhead transcription factor FOXM1 and HER2 in human breast cancer , 2008, BMC Cancer.
[48] Olufunmilayo I. Olopade,et al. Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations , 2007, Nature Reviews Cancer.
[49] M. Esteller. Epigenetic gene silencing in cancer: the DNA hypermethylome. , 2007, Human molecular genetics.
[50] C. Prives,et al. Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function? , 2007, Oncogene.
[51] J. Jónasson,et al. Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancer , 2006, Breast Cancer Research.
[52] M. Fraga,et al. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[53] L. Trümper. From bench to bedside , 2005, Medizinische Klinik.
[54] C. Pilarsky,et al. Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. , 2004, Neoplasia.
[55] S. McMahon,et al. Analysis of genomic targets reveals complex functions of MYC , 2004, Nature Reviews Cancer.
[56] Gordon K Smyth,et al. Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .
[57] M. Bulyk. Computational prediction of transcription-factor binding site locations , 2003, Genome Biology.
[58] T. Volkert,et al. E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. , 2002, Genes & development.
[59] Xin Chen,et al. TRANSFAC: an integrated system for gene expression regulation , 2000, Nucleic Acids Res..
[60] B. Biesecker,et al. Breast cancer susceptibility genes. BRCA1 and BRCA2. , 1998, Medicine.
[61] R. Tibshirani. Regression Shrinkage and Selection via the Lasso , 1996 .
[62] Y. Benjamini,et al. Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .
[63] A. Patel,et al. myc function and regulation. , 1992, Annual review of biochemistry.