The Origins of Evolutionary Innovations: A Theory of Transformative Change in Living Systems

1. Introduction 2. Metabolic innovation 3. Innovation through regulation 4. Novel molecules 5. The origins of evolutionary innovation 6. Genotype networks, self-organization, and natural selection 7. A synthesis of neutralism and selectionism 8. The role of robustness for innovation 9. Gene duplications and innovation 10. The role of recombination 11. Environmental change in adaptation and innovation 12. Evolutionary constraints and genotype spaces 13. Phenotypic plasticity and innovation 14. Towards continuous genotype spaces 15. Evolvable technology and innovation 16. Summary and outlook Bibliography Index