Successful treatment of deep sternal infections following open heart surgery by bilateral pectoralis major flaps.

OBJECTIVES Severe sternum necrosis requiring extended resection necessitates plastic reconstruction of the resulting defect and stabilization of the chest. We analyzed the outcome of patients undergoing bilateral pectoralis major flap repair on functional and cosmetic results, chest stabilization and pulmonary function. METHODS Twelve patients undergoing cardiac surgery between 1997 and 2001 suffered from a deep mediastinal wound infection and sternum necrosis. After a mean of two attempts of extensive wound debridement, all 12 patients underwent complete sternal resection with plastic reconstruction by bilateral pectoralis major flaps. Risk factors were obesity (n=10) and diabetes (n=11). Six months postoperatively patients underwent physical examination, pulmonary function testing and functional CT scan. RESULTS Three patients died in hospital (two septic multiorgan failure, one heart failure) and nine were discharged with complete wound closure. One patient suffered a lethal stroke during follow-up. At 6-month follow-up no recurrent sternum infection had occurred. Chest stability was satisfactory without impairment of pulmonary function (VC 77.5+/-12.1% at follow-up vs 77.8+/-12.5% preoperatively). Mobility and force of arms and shoulder were adequate; at CT scan the maximum distance change between the former sternoclavicular joint in inspiration versus expiration was minimal. Quality of life questionnaires showed no significant limitations except a disturbed sleep and mild restriction of executing hobbies and social activities. CONCLUSIONS Bilateral pectoralis major flap repair is a safe technique to cure severe mediastinitis necessitating complete sternal resection. Wounds close without extensive reconstructive surgery. Cosmetic results as well as stabilization of the chest were good. Patients reported an almost uncompromised quality of life without respiratory impairment.

[1]  Craig R. Smith,et al.  Single‐Stage Management of 74 Consecutive Sternal Wound Complications with Pectoralis Major Myocutaneous Advancement Flaps , 1994, Plastic and reconstructive surgery.

[2]  T. Treasure,et al.  Factors predisposing to wound infection in cardiac surgery. A prospective study of 517 patients. , 1987, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[3]  T. Demmy,et al.  Recent experience with major sternal wound complications. , 1990, The Annals of thoracic surgery.

[4]  T. Centella,et al.  Muscle flap reconstruction for the treatment of major sternal wound infections after cardiac surgery: a 10-year analysis. , 1999, Scandinavian journal of plastic and reconstructive surgery and hand surgery.

[5]  R. Thurer,et al.  The management of mediastinal infection following cardiac surgery. An experience utilizing continuous irrigation with povidone-iodine. , 1974, The Journal of thoracic and cardiovascular surgery.

[6]  F. Nahai,et al.  Management of the infected median sternotomy wound with muscle flaps. The Emory 20-year experience. , 1997, Annals of surgery.

[7]  M. Granick,et al.  Bipedicle Muscle Flaps in Sternal Wound Repair , 1998, Plastic and reconstructive surgery.

[8]  S. Torii,et al.  Results of omental flap transposition for deep sternal wound infection after cardiovascular surgery. , 1998, Annals of surgery.

[9]  F. Spencer,et al.  Sternal and costochondral infections following open-heart surgery. A review of 2,594 cases. , 1976, The Journal of thoracic and cardiovascular surgery.

[10]  N. Doll,et al.  Mediastinitis and cardiac surgery--an updated risk factor analysis in 10,373 consecutive adult patients. , 2002, The Thoracic and cardiovascular surgeon.

[11]  R. Engelman,et al.  Mediastinitis following open-heart surgery. Review of two years' experience. , 1973, Archives of surgery.

[12]  A. Cordell,et al.  A prospective study of sternal wound complications. , 1984, The Annals of thoracic surgery.

[13]  M. Mack,et al.  Risk factors for operative mortality and sternal wound infection in bilateral internal mammary artery grafting. , 1994, The Journal of thoracic and cardiovascular surgery.

[14]  I. Wiklund,et al.  Impact of coronary artery bypass grafting on various aspects of quality of life. , 1997, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[15]  W. Saggau,et al.  Analysis of infections after cardiac surgery , 2000 .

[16]  D. Loisance,et al.  Omental transposition for closure of median sternotomy following severe mediastinal and vascular infection. , 1985, Chest.

[17]  N. Kouchoukos,et al.  Risks of bilateral internal mammary artery bypass grafting. , 1990, The Annals of thoracic surgery.

[18]  C. S. Campbell,et al.  Treatment of mediastinitis: early modified Robicsek closure and pectoralis major advancement flaps. , 1998, The Annals of thoracic surgery.

[19]  L. S. Newman,et al.  Suppurative mediastinitis after open heart surgery. A case control study of risk factors. , 1988, Chest.

[20]  E. Jones,et al.  Mediastinitis after cardiac valve operations. Impact upon survival. , 1985, The Journal of thoracic and cardiovascular surgery.